Results 61 to 70 of about 281,748 (215)

Heart rate changes after phlebotomy in polycythaemia vera and healthy donors: An observational case‐crossover pilot study

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Haemoglobin plays a crucial role in oxygen transport, and any acute deviation will trigger compensatory hemodynamic functions. While the consequences of anaemia are well documented, the effects of haemoglobin reduction in individuals without anaemia remain less explored. Patients with polycythaemia vera and healthy blood donors, who
Rik P. B. Tonino   +3 more
wiley   +1 more source

Thrombotic and Atherogenetic Predisposition in Polyglobulic Donors

open access: yesBiomedicines, 2022
This work analyses the results of research regarding the predisposition of genetic hematological risks associated with secondary polyglobulia. The subjects of the study were selected based on shared laboratory markers and basic clinical symptoms.
Nikola Slaninova   +8 more
doaj   +1 more source

Comparison of different criteria for the diagnosis of primary myelofibrosis reveals limited clinical utility for measurement of serum lactate dehydrogenase

open access: yesHaematologica, 2010
Primary myelofibrosis shows histological and pathogenetic overlap with essential thrombocythemia and polycythemia vera. Several diagnostic classifications have been proposed for primary myelofibrosis, although little is known about their clinical utility.
Philip A. Beer   +2 more
doaj   +1 more source

Long‐Term Safety Profile of Ruxolitinib in Chronic Myeloproliferative Neoplasms: A Comprehensive Real‐World Analysis

open access: yeseJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Ruxolitinib is a key therapeutic option for patients with myeloproliferative neoplasms. Its short‐term toxicity profile is well‐established, but long‐term safety data remains scarce. Methods We aimed to evaluate toxicity associated with long‐term exposure to ruxolitinib (defined as 3 years or longer) through a dual‐cohort ...
Alberto Blanco‐Sánchez   +8 more
wiley   +1 more source

Oral Idasanutlin in Patients with Polycythemia Vera.

open access: yesBlood, 2019
A limited number of drugs are available to treat patients with polycythemia vera (PV) and essential thrombocythemia (ET). We attempted to identify alternative agents that may target abnormalities within malignant hematopoietic stem and progenitor cells ...
J. Mascarenhas   +12 more
semanticscholar   +1 more source

Common Themes and Uncertainties in Management of Secondary Polycythaemia: An International Clinician Survey of Practice

open access: yeseJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Secondary and idiopathic polycythaemia is far more common than polycythaemia vera. Whilst venesection for polycythaemia vera has a robust evidence base, the data supporting this treatment for secondary and/or idiopathic polycythaemia are limited to small single‐arm studies showing transient improvement in symptoms or physiologic ...
Phillip LR Nicolson   +7 more
wiley   +1 more source

Evaluating the effect of anti–cancer nano drugs dosage and reduced leukemia and polycythemia vera levels on trend of the human blood and bone marrow cancers under synchrotron radiation

open access: yesTrends in Research, 2019
Leukemia is a cancer of the blood and bone marrow; there are many types of leukemia, depending on which type of white blood cell is involved. Treatment varies with the type and stage of disease.
A. Heidari, R. Gobato
semanticscholar   +1 more source

Impact of Donor Type on Outcomes After Allogeneic Hematopoietic Cell Transplantation in Myelofibrosis: A Study on Behalf of the Chronic Malignancies Working Party of the EBMT

open access: yesAmerican Journal of Hematology, Volume 100, Issue 11, Page 2028-2039, November 2025.
ABSTRACT Selecting the optimal donor is crucial for optimizing results of allogeneic hematopoietic cell transplantation (allo‐HCT). We analyzed outcomes based on donor type in 2809 myelofibrosis (MF) patients undergoing first allo‐HCT between 2015 and 2021 at EBMT centers.
Juan Carlos Hernández‐Boluda   +24 more
wiley   +1 more source

Dysregulated iron metabolism in polycythemia vera: etiology and consequences

open access: yesLeukemia, 2018
Polycythemia vera (PV) is a chronic myeloproliferative neoplasm. Virtually all PV patients are iron deficient at presentation and/or during the course of their disease.
Y. Ginzburg   +5 more
semanticscholar   +1 more source

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