Myelopathy due to Spinal Extramedullary Hematopoiesis in a Patient with Polycythemia Vera
Extramedullary hematopoiesis (EMH) occasionally occurs in patients exhibiting hematological disorders with decreased hematopoietic efficacy. EMH is rarely observed in the spinal epidural space and patients are usually asymptomatic.
Shuhei Ito +10 more
doaj +1 more source
Naltrexone: a Novel Approach to Pruritus in Polycythemia Vera [PDF]
Newsha Nikzad
openalex +1 more source
Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei +32 more
wiley +1 more source
We tested the hypothesis that levels of pentraxin high sensitivity C-reactive protein and pentraxin 3 might be correlated with cardiovascular complications in patients with essential thrombocythemia and polycythemia vera.
Tiziano Barbui +15 more
doaj +1 more source
Nosocomial Co-Transmission of Avian Influenza A(H7N9) and A(H1N1)pdm09 Viruses between 2 Patients with Hematologic Disorders [PDF]
A nosocomial cluster induced by co-infections with avian influenza A(H7N9) and A(H1N1)pdm09 (pH1N1) viruses occurred in 2 patients at a hospital in Zhejiang Province, China, in January 2014.
Bi, Y +21 more
core +1 more source
Vaping‐Induced Erythrocytosis Resolved With Cessation of e‐Cigarette Use
ABSTRACT Vaping use is a global health concern with multiple adverse general health effects. We report a young man with vaping‐induced erythrocytosis that resolved following cessation of e‐cigarette use. Presence of erythrocytosis without a history of hypoxia or associated medications should prompt a thorough investigation for secondary causes ...
Jenyvette Hsia +4 more
wiley +1 more source
Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis
Here we critically evaluate the role of elevated hematocrit as the principal determinant of thrombotic risk in polycythemia and erythrocytosis, defined by an expansion of red cell mass.
Victor R. Gordeuk +2 more
doaj +1 more source
Two-hit model of leukemogenesis in the evolution of polycythemia vera to acute myeloid leukemia [PDF]
Polycythemia vera (PV) is a chronic myeloproliferative disorder that can evolve to marrow fibrosis or acute leukemia (AML). Cytogenetic alterations can be detected in around 25% of patients at diagnosis and in up to 50% of those with progression.
Chauffaille, Maria de Lourdes Lopes Ferrari +2 more
core +1 more source
Transient Spinal Cord Ischemia as Presenting Manifestation of Polycythemia Vera
Spinal arterial vascularization is supplied by a large anastomotic net, making spinal ischemic events far less common than ischemic cerebral strokes. Polycythemia vera, due to blood hyperviscosity and activated platelet aggregation, is associated with a ...
Sónia Costa +3 more
doaj +1 more source
Polycythemia Vera: New Diagnostic Concept and Its Types
Polycythemia vera (PV) is a clonal Ph-negative myeloproliferative disorder characterized by excessive myeloid proliferation of three hematopoietic cell lineages leading to ineffective myelopoiesis.
Alla Mikhailovna Kovrigina, V. V. Baikov
doaj +1 more source

