Results 81 to 90 of about 287,802 (318)
Primary myelofibrosis with increased haemoglobin concentration at presentation
British Journal of Haematology, EarlyView.Subjects with primary myelofibrosis and elevated haemoglobin levels at diagnosis tend to have longer survival rates (OS) and blast transformation‐free survival (BTFS) than those with normal or reduced haemoglobin levels. Summary One hundred of 963 consecutive registrants with primary myelofibrosis (PMF) in the Pavia‐CSM database had haemoglobin ...
Giovanni Barosi +8 more
wiley +1 more source
Haematologica, 2010 Primary myelofibrosis shows histological and pathogenetic overlap with essential thrombocythemia and polycythemia vera. Several diagnostic classifications have been proposed for primary myelofibrosis, although little is known about their clinical utility.
Philip A. Beer +2 more
doaj +1 more source
Myeloproliferative neoplasms: a review of diagnostic criteria and clinical aspects [PDF]
, 2010 Chronic myeloproliferative disorders, currently called myeloproliferative neoplasms (MPN), according to the 4th edition of the World Health Organization (WHO) classification are clonal diseases of hematopoietic stem cells, in which there is increased ...
Chauffaille, Maria de Lourdes Lopes Ferrari
core +1 more source
Trends in Research, 2019 Leukemia is a cancer of the blood and bone marrow; there are many types of leukemia, depending on which type of white blood cell is involved. Treatment varies with the type and stage of disease.
A. Heidari, R. Gobato
semanticscholar +1 more source
British Journal of Haematology, EarlyView.A proposed model of Setd2 deficiency and KrasG12D/+ mutation synergism in the pathogenesis of juvenile myelomonocytic leukaemia (JMML). KrasG12D/+ mutation instigates constitutive activation of the RAS‐ERK1/2 signalling pathway, and Setd2 ablation in the KrasG12D/+ mutant background further hyperactivates the RAS‐ERK1/2 signalling pathway, leading to ...
Gustave Munyurangabo +11 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Acute myocardial infarction (AMI) with essential thrombocythemia (ET) or polycythemia vera is rare, and there are scarce real‐world data on its management and impact on in‐hospital outcomes.
Jing Wu +6 more
doaj +1 more source
Oral Idasanutlin in Patients with Polycythemia Vera.
Blood, 2019 A limited number of drugs are available to treat patients with polycythemia vera (PV) and essential thrombocythemia (ET). We attempted to identify alternative agents that may target abnormalities within malignant hematopoietic stem and progenitor cells ...
J. Mascarenhas +12 more
semanticscholar +1 more source
Cell Proliferation, EarlyView.CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far +4 more
wiley +1 more source
Patient Characteristics, Healthcare Contacts and Drug Use in Polycythaemia Vera in Denmark
European Journal of Haematology, EarlyView.ABSTRACT Objective Patients with polycythaemia vera (PV) may experience symptoms and cardiovascular complications before receiving a diagnosis. Understanding the associated patterns of healthcare and drug utilisation may help detect patients who need diagnostic workup.
Karoline Mathilde Lundgaard +4 more
wiley +1 more source
Myelopathy due to Spinal Extramedullary Hematopoiesis in a Patient with Polycythemia Vera
Case Reports in Orthopedics, 2017 Extramedullary hematopoiesis (EMH) occasionally occurs in patients exhibiting hematological disorders with decreased hematopoietic efficacy. EMH is rarely observed in the spinal epidural space and patients are usually asymptomatic.
Shuhei Ito +10 more
doaj +1 more source