Results 41 to 50 of about 1,287 (198)

Combination Therapy With Polydeoxyribonucleotide and Pirfenidone Alleviates Symptoms of Acute Respiratory Distress Syndrome in Human Lung Epithelial A549 Cells [PDF]

International Neurourology Journal, 2020
Purpose Acute respiratory distress syndrome (ARDS) is characterized by its acute onset of symptoms such as bilateral pulmonary infiltrates, severe hypoxemia, and pulmonary edema.
Jae-Joon Hwang, Il-Gyu Ko, Jun-Jang Jin, Lakkyong Hwang, Sang-Hoon Kim, Jung Won Jeon, Seung Sook Paik, Bok Soon Chang, Cheon Woong Choi   +8 more
doaj   +1 more source

Polydeoxyribonucleotide Injection as an Alternative to Surgery in Hypoxic Conditions [PDF]

International Neurourology Journal
Fabiola Cassaro, Santi D’Antoni, Pietro Impellizzeri, Carmelo Romeo, Salvatore Arena   +4 more
doaj   +2 more sources

The Origin of Life: Models and Data. [PDF]

, 2017
A general framework for conventional models of the origin of life (OOL) is the specification of a 'privileged function.' A privileged function is an extant biological function that is excised from its biological context, elevated in importance over other
Lanier, Kathryn A, Williams, Loren Dean
core   +1 more source

A Photocurable Polysaccharide-Based Hydrogel Delivery of Polydeoxyribonucleotide-Loaded Vectors for Wound Treatment

Molecules, 2023
The wounds caused by war, accidents, and diseases require timely and effective treatment. Polysaccharides, as natural macromolecules, have good biocompatibility and unique functions, and are excellent substrates for constructing new wound dressings ...
Zonghui Li, Xiaojun Ma, Qiang Gao, Mingxin Zhang, Hao Hu   +4 more
doaj   +1 more source

Mutation patterns of amino acid tandem repeats in the human proteome [PDF]

, 2006
Background: Amino acid tandem repeats are found in nearly one-fifth of human proteins. Abnormal expansion of these regions is associated with several human disorders.
Albà Soler, Mar, Guigó Serra, Roderic, Mularoni, Loris   +2 more
core   +2 more sources

Targeting Adenosine Receptor by Polydeoxyribonucleotide: An Effective Therapeutic Strategy to Induce White-to-Brown Adipose Differentiation and to Curb Obesity

Pharmaceuticals, 2021
Obesity is a worldwide chronic metabolic disease characterized by an abnormal fat accumulation and represents one of the main risk factors for several diseases.
Federica Mannino, Giovanni Pallio, Alessandra Bitto, Domenica Altavilla, Letteria Minutoli, Violetta Squadrito, Vincenzo Arcoraci, Domenico Antonio Giorgi, Igor Pirrotta, Francesco Squadrito, Natasha Irrera   +10 more
doaj   +1 more source

In vitro polydeoxyribonucleotide effects on human pre‐adipocytes [PDF]

Cell Proliferation, 2008
Abstract.  Objectives: Adipose tissue is the most abundant and accessible source of adult stem cells. Human processed lipoaspirate contains pre‐adipocytes that possess one of the a characteristic pathways of multipotent adult stem cells and are able to differentiate in vitro into mesenchymal and also neurogenic lineages.
RAPOSIO E, GUIDA, CHIARA, CORADEGHINI R, SCANAROTTI C, PARODI A, BALDELLI, ILARIA, FIOCCA, ROBERTO, SANTI, PIERLUIGI   +7 more
openaire   +3 more sources

Viscosupplementation in the Therapy for Osteoarthritic Knee

Applied Sciences, 2021
Osteoarthritis (OA) is a degenerative disease that is spreading worldwide due to an aging population. This is not simply a disease caused by worn out joints, but a complex disease accompanied by various mechanisms such as inflammatory reactions.
Junghyun Park, Hue Jung Park, Min Cheol Rho, Jin Joo   +3 more
doaj   +1 more source

Activation of A2A Receptor by PDRN Reduces Neuronal Damage and Stimulates WNT/β-CATENIN Driven Neurogenesis in Spinal Cord Injury

Frontiers in Pharmacology, 2018
Spinal cord injury (SCI) is a complex clinical and progressive condition characterized by neuronal loss, axonal destruction and demyelination. In the last few years, adenosine receptors have been studied as a target for many diseases, including ...
Natasha Irrera, Vincenzo Arcoraci, Federica Mannino, Giovanna Vermiglio, Giovanni Pallio, Letteria Minutoli, Gianluca Bagnato, Giuseppe Pio Anastasi, Emanuela Mazzon, Placido Bramanti, Francesco Squadrito, Domenica Altavilla, Alessandra Bitto   +12 more
doaj   +1 more source

Therapeutic effects of polydeoxyribonucleotide in an in vitro neuronal model of ischemia/reperfusion injury [PDF]

, 2023
Polydeoxyribonucleotide (PDRN) is an agonist that selectively stimulates adenosine A2A receptor (ADORA2A), which suppresses inflammatory responses. Ischemia/reperfusion (I/R) injury plays a major role in the pathogenesis of ischemic stroke by inducing ...
조성래
core   +1 more source