Results 61 to 70 of about 1,287 (198)

Study of the Efficacy of Artificial Intelligence Algorithm-Based Analysis of the Functional and Anatomical Improvement in Polynucleotide Treatment in Knee Osteoarthritis Patients: A Prospective Case Series. [PDF]

open access: yes, 2022
Knee osteoarthritis (OA) is one of the most common degenerative diseases in old age. Recent studies have suggested new treatment approaches dealing with subchondral remodeling, which is a typical feature of OA progression.
Jang, Ji   +4 more
core   +1 more source

The adjunctive effect of polydeoxyribonucleotide on bone formation in alveolar ridge preservation: A pre-clinical in vivo study [PDF]

open access: yes
AimThis study investigated the adjunctive effect of polydeoxyribonucleotide (PDRN) on bone formation in alveolar ridge preservation (ARP) sockets.Materials and MethodsBoth mandibular second, third and fourth premolars of eight beagle dogs were randomly ...
Ko Young-Chang   +5 more
core   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

A Deoxyribonuclease from Calf Spleen. II. Mode of Action [PDF]

open access: yes, 1957
When highly polymerized deoxyribonucleic acid is digested with pancreatic DNase and the digest further degraded with phosphodiesterase from intestinal mucose or snake venom, the mononucleotides formed are 5'-phosphates.
Koerner, James F., Sinsheimer, Robert L.
core  

Efficacy and Safety of Intra‐Articular Therapies for Temporomandibular Disorders: A Systematic Review and Meta‐Analysis

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to evaluate the most effective minimally invasive intra‐articular procedure for reducing pain and improving maximum mouth opening (MMO) in individuals diagnosed with painful articular TMD, specifically TMJ osteoarthritis and/or internal derangement.
Mateus Gaya dos Santos   +5 more
wiley   +1 more source

Real‐World Use of Polynucleotide Injections in Scar Prevention and Management: A Nationwide Survey of Korean Society for Anti‐Aging Dermatology (KAAD) Dermatologists

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Scarring is a common dermatologic concern with both aesthetic and functional implications. Polynucleotide (PN)‐based injectables have emerged as medical devices in dermatologic practice; however, real‐world evidence on their use in scar management remains limited.
Nark Kyoung Rho   +3 more
wiley   +1 more source

The Effect of Polydeoxyribonucleotide on Chronic Non-healing Wound of an Amputee: A Case Report [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2018
Polydeoxyribonucleotide (PDRN) is safe and effective in wound healing, cellular growth, synthesis of extracellular matrix protein, and inflammation reduction via activation of adenosine A2 receptors. We report a 28-year-old male patient treated with PDRN
Junho Shin   +3 more
doaj   +1 more source

Učinak autolognog presatka adipoznog tkiva na proces cijeljenja kritičnog defekta dijafizne kosti kokoši [PDF]

open access: yes, 2023
Treatment of large bone defects and incurable fractures is a challenging clinical problem. A novel approaches in bone engineering is the use of adipose-derived stem cells and adipose tissue.
Cvitković, Denis   +9 more
core   +2 more sources

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han   +5 more
wiley   +1 more source

Advanced Regenerative Drainage and Immunomodulatory Protocol for Dermal Filler–Induced Skin Necrosis: A Prospective Clinical Case Series

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background The widespread use of hyaluronic acid (HA) dermal fillers has been accompanied by an increase in vascular complications, including ischemia and cutaneous necrosis. Although uncommon, filler‐induced vascular compromise represents one of the most severe adverse events in aesthetic medicine and requires immediate recognition and ...
Macarena Olivares   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy