Results 171 to 180 of about 14,397 (234)

Polyene Antifungals

open access: yes, 2016
Determining the optimal polyene antifungal dosing in obese patients is considered highly challenging. Limited data are available to describe the pharmacokinetics of polyene antifungals in these patients. However, polyene antifungals demonstrate widely variable pharmacokinetics in various clinical conditions.
Jamal, Janattul-Ain, Roberts, Jason A.
openaire   +4 more sources

Bifunctional Polyene Cyclizations: Synthetic Studies on Pimarane Natural Products

open access: yesChemistry - A European Journal, 2021
Polyene cyclizations generate molecular complexity from a linear polyene in a single step. While methods to initiate these cyclizations have been continuously expanded and improved over the years, the majority of polyene substrates are still limited to ...
Julian M Feilner   +2 more
exaly   +2 more sources

The Field-Effect Transistor Based on a Polyyne–Polyene Structure Obtained via PVDC Dehydrochlorination

open access: yesJournal of Composites Science, 2023
We report on the formation of the field-effect transistor based on a polyyne–polyene structure. Polyvinylidene chloride (PVDC) drop casting and its subsequent dehydrochlorination in KOH solution allowed for the formation of porous polyyne&ndash ...
Oleg A Streletskiy   +2 more
exaly   +2 more sources

The Longest Polyene

Organic Letters, 2012
A microwave assisted Wittig reaction allowed the synthesis, in good yields, of the longest polyene so far recorded with 27 conjugated double bonds. The synthesis of this stable, well-soluble polyene represents a noteworthy step in the direction of ultimate λ(max).
Muhammad, Zeeshan   +3 more
openaire   +2 more sources

Enantioselective polyene cyclizations

Organic & Biomolecular Chemistry, 2016
A comprehensive review covering the field of enantioselective polyene cyclizations.
Chad N, Ungarean   +2 more
openaire   +2 more sources

Quantum interference in polyenes

The Journal of Chemical Physics, 2014
The explicit form of the zeroth Green's function in the Hückel model, approximated by the negative of the inverse of the Hückel matrix, has direct quantum interference consequences for molecular conductance. We derive a set of rules for transmission between two electrodes attached to a polyene, when the molecule is extended by an even number of carbons
Yuta Tsuji   +3 more
openaire   +2 more sources

Biomimetic studies on polyenes

Org. Biomol. Chem., 2003
The crispatenes and SNF4435 C&D are complex polypropionate derived natural products. The core structures of these compounds along with a complex unnatural structure can be easily prepared from a common polyene precursor simply by variation of the reaction conditions.
John E, Moses   +4 more
openaire   +2 more sources

Biomimetic polyene cyclizations

Bioorganic Chemistry, 1976
AbstractCertain polyenic substances having trans olefinic bonds in a 1,5 relationship can be induced to undergo stereospecific, non‐enzymic, cationic cyclization to give polycyclic products with all‐trans (“natural”) configuration. These transformations appear to mimic in principle the biogenetic conversion of squalene into polycyclic triterpenoids ...
openaire   +2 more sources

The Polyene Antifungal Antibiotics

1963
During the early 1950’s there appeared reports, from time to time of the presence among the products elaborated by actinomycetes of antifungal antibiotics which exhibited very similar and very characteristic multipeaked ultraviolet absorption spectra. In 1954, with a good number of examples on record, these spectra were analyzed and identified as those
W, OROSHNIK, A D, MEBANE
openaire   +2 more sources

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