Results 41 to 50 of about 14,397 (234)
Alkine in Polyene Zyklisierungen
, 2021 Polyene cyclisations are among the most powerful and intriguing chemical transformations. Used by chemists and nature alike, polyene cyclisations are key to synthesise a wealth of complex polycyclic scaffolds.
Schmidhammer, Elias
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Genome-Guided Discovery of Pretilactam from Actinosynnema pretiosum ATCC 31565
Molecules, 2019 Actinosynnema is a small but well-known genus of actinomycetes for production of ansamitocin, the payload component of antibody-drug conjugates against cancers.
Jing Wang +9 more
doaj +1 more source
Advanced Science, EarlyView.We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai +8 more
wiley +1 more source
Novel polyene carboxylic acids from Streptomyces
, 2004 Reinvestigation of the production of the unusual polyene carboxylic acid serpentene (1a) from Streptomyces sp. Tu 3851 revealed the presence of additional polyene carboxylic acids.
Bode, H., Wenzel, S.
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AgriFood: Journal of Agricultural Products for Food, EarlyView.Excipient emulsion systems improve carotenoid solubilization, protect against degradation, and enhance gastrointestinal absorption through optimized formulation and digestion behavior. ABSTRACT Carotenoids are bioactive compounds that contribute to human health through antioxidant, provitamin A, and disease‐preventive effects.
Tugce Ceyhan +3 more
wiley +1 more source
Über Kumulene, XII. cis-Polyene durch Partialhydrierung von Kumulenen
, 1960 Die katalytische Hydrierung von Kumulenen mit dem Lindlar-Katalysator liefert die entsprechenden Polyene. In den dafür in Frage kommenden Fällen erhielt man dabei noch unbekannte cis-Polyene, die sich durch Belichtung in die schon bekannten trans-Polyene
Kuhn, R., Fischer, H.
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The polyene macrolide antibiotics [PDF]
Postgraduate Medical Journal, 1979 Summary The mode of action of the polyene antibiotics is reviewed together with the effect of genetic and environmental factors on sensitive organisms. The future prospects of polyenes in the treatment of systemic mycoses are considered.
openaire +2 more sources
Angewandte Chemie, EarlyView.Oberfläche enthüllt: Verkokung ist die zentrale Ursache für die Deaktivierung von Zeolithkatalysatoren. Mithilfe von In‐situ‐XPS in Verbindung mit ergänzenden Methoden identifizieren wir Unterschiede in der Bildungskinetik und Zusammensetzung von Oberflächenkoks auf industriell relevanten ZSM‐5‐Katalysatoren während der MTH‐Umwandlung und zeigen damit ...
Luca Artiglia +6 more
wiley +1 more source
An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety. [PDF]
PLoS ONE, 2016 Amphotericin B is the most potent antimycotic known to date. However due to its large collateral toxicity, its use, although long standing, had been limited. Many attempts have been made to produce derivatives with reduced collateral damage.
Armando Antillón +21 more
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Total Synthesis of the Polyene Macrolide Roflamycoin
, 2016 Total Synthesis of the Polyene Macrolide ...
Uday R. Khire (2999712) +2 more
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