Results 21 to 30 of about 24,760 (225)

New Rimocidin/CE-108 Derivatives Obtained by a Crotonyl-CoA Carboxylase/Reductase Gene Disruption in Streptomyces diastaticus var. 108: Substrates for the Polyene Carboxamide Synthase PcsA. [PDF]

open access: yesPLoS ONE, 2015
The rimJ gene, which codes for a crotonyl-CoA carboxylase/reductase, lies within the biosynthetic gene cluster for two polyketides belonging to the polyene macrolide group (CE-108 and rimocidin) produced by Streptomyces diastaticus var. 108.
Leticia Escudero   +5 more
doaj   +1 more source

Polyene Antibiotics Physical Chemistry and Their Effect on Lipid Membranes; Impacting Biological Processes and Medical Applications

open access: yesMembranes, 2022
This review examined a collection of studies regarding the molecular properties of some polyene antibiotic molecules as well as their properties in solution and in particular environmental conditions.
Tammy Haro-Reyes   +5 more
doaj   +1 more source

Improvement of the thermal properties of pitch by waste plastic (polyvinyl chloride) addition

open access: yesJournal of Materials Research and Technology, 2021
To modify the thermal properties of pitch by adding polyvinyl chloride (PVC), co-pyrolysis of PVC and coal tar pitch was performed. PVC decomposes into HCl and de-HCl PVC (polyene) above 200 °C, and these substances affect the synthesis behavior of coal ...
Yun Jeong Choi, Ji Hong Kim, Ji Sun Im
doaj   +1 more source

Inhibiting Effect of Macrolide Polyene Antibiotics on Reproduction of Viruses

open access: yesАнтибиотики и Химиотерапия, 2020
The review provides a comparative analysis of the inhibitory effect of macrocyclic polyene antibiotics on the reproductive properties of some viruses of various structures — vesicular stomatitis virus (VSV), human immunodeficiency virus (HIV ...
A. A. Bagirova   +3 more
doaj   +1 more source

Orbital Optimization in the Density Matrix Renormalization Group, with applications to polyenes and \beta-carotene [PDF]

open access: yes, 2007
In previous work we have shown that the Density Matrix Renormalization Group (DMRG) enables near-exact calculations in active spaces much larger than are possible with traditional Complete Active Space algorithms.
Debashree Ghosh   +5 more
core   +3 more sources

Biosynthetic engineering of the antifungal, anti-MRSA auroramycin

open access: yesMicrobial Cell Factories, 2020
Using an established CRISPR-Cas mediated genome editing technique for streptomycetes, we explored the combinatorial biosynthesis potential of the auroramycin biosynthetic gene cluster in Streptomyces roseosporous.
Wan Lin Yeo   +13 more
doaj   +1 more source

New Glycosylated Polyene Macrolides: Refining the Ore from Genome Mining

open access: yesAntibiotics, 2022
Glycosylated polyene macrolides include effective antifungal agents, such as pimaricin, nystatin, candicidin, and amphotericin B. For the treatment of systemic mycoses, amphotericin B has been described as a gold-standard antibiotic because of its potent
Patrick Caffrey, Mark Hogan, Yuhao Song
doaj   +1 more source

New Horizons in Antifungal Therapy

open access: yesJournal of Fungi, 2016
Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics.
Kaila M. Pianalto, J. Andrew Alspaugh
doaj   +1 more source

Model for Triplet State Engineering in Organic Light Emitting Diodes

open access: yes, 2014
Engineering the position of the lowest triplet state (T1) relative to the first excited singlet state (S1) is of great importance in improving the efficiencies of organic light emitting diodes and organic photovoltaic cells.
Prodhan, Suryoday   +2 more
core   +1 more source

Prediction of infrared light emission from pi-conjugated polymers: a diagrammatic exciton basis valence bond theory

open access: yes, 2002
There is currently a great need for solid state lasers that emit in the infrared, as this is the operating wavelength regime for applications in telecommunications.
A. Shukla   +28 more
core   +1 more source

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