Results 21 to 30 of about 14,397 (234)
Antibiotics, 2023 The biosynthesis of polyene macrolides, which are natural products produced by soil actinomycetes, have been extensively explored, and recent studies have focused on the effects of post–polyketide synthase (PKS) modifications to polyene macrolides on ...
Liqin Qiao +3 more
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Photoinduced Dynamics of 13,13′-Diphenylpropyl-β-carotene
Molecules, 2023 Carotenoids are ubiquitous pigment systems in nature which are relevant to a range of processes, such as photosynthesis, but the detailed influence of substitutions at the polyene backbone on their photophysics is still underexplored.
Sangho Koo +5 more
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New Horizons in Antifungal Therapy
Journal of Fungi, 2016 Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics.
Kaila M. Pianalto, J. Andrew Alspaugh
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New Rimocidin/CE-108 Derivatives Obtained by a Crotonyl-CoA Carboxylase/Reductase Gene Disruption in Streptomyces diastaticus var. 108: Substrates for the Polyene Carboxamide Synthase PcsA. [PDF]
PLoS ONE, 2015 The rimJ gene, which codes for a crotonyl-CoA carboxylase/reductase, lies within the biosynthetic gene cluster for two polyketides belonging to the polyene macrolide group (CE-108 and rimocidin) produced by Streptomyces diastaticus var. 108.
Leticia Escudero +5 more
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Membranes, 2022 This review examined a collection of studies regarding the molecular properties of some polyene antibiotic molecules as well as their properties in solution and in particular environmental conditions.
Tammy Haro-Reyes +5 more
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Improvement of the thermal properties of pitch by waste plastic (polyvinyl chloride) addition
Journal of Materials Research and Technology, 2021 To modify the thermal properties of pitch by adding polyvinyl chloride (PVC), co-pyrolysis of PVC and coal tar pitch was performed. PVC decomposes into HCl and de-HCl PVC (polyene) above 200 °C, and these substances affect the synthesis behavior of coal ...
Yun Jeong Choi, Ji Hong Kim, Ji Sun Im
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Inhibiting Effect of Macrolide Polyene Antibiotics on Reproduction of Viruses
Антибиотики и Химиотерапия, 2020 The review provides a comparative analysis of the inhibitory effect of macrocyclic polyene antibiotics on the reproductive properties of some viruses of various structures — vesicular stomatitis virus (VSV), human immunodeficiency virus (HIV ...
A. A. Bagirova +3 more
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, 2021 A highly modular synthetic strategy to the heronamide C-type polyene macrolactams was established by synthesizing 8-deoxyheronamide C (2). The developed strategy enabled not only the total synthesis of 8-deoxyheronamide C (2) but also the unified ...
Shinichi, Nishimura +9 more
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Biosynthetic engineering of the antifungal, anti-MRSA auroramycin
Microbial Cell Factories, 2020 Using an established CRISPR-Cas mediated genome editing technique for streptomycetes, we explored the combinatorial biosynthesis potential of the auroramycin biosynthetic gene cluster in Streptomyces roseosporous.
Wan Lin Yeo +13 more
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New Glycosylated Polyene Macrolides: Refining the Ore from Genome Mining
Antibiotics, 2022 Glycosylated polyene macrolides include effective antifungal agents, such as pimaricin, nystatin, candicidin, and amphotericin B. For the treatment of systemic mycoses, amphotericin B has been described as a gold-standard antibiotic because of its potent
Patrick Caffrey, Mark Hogan, Yuhao Song
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