Results 11 to 20 of about 24,760 (225)

Liposomal-polyene preliposomal powder and method for its preparation [PDF]

open access: yes, 1993
A method is disclosed for preparing a stable preliposomal powder which, when reconstituted with water or saline solution, forms a suspension of liposomes containing a polyene drug, such as nystatin. The method involves the steps of combining at least one
Lenk, Robert P.   +2 more
core   +1 more source

Charge Transport through Polyene Self-Assembled Monolayers from Multiscale Computer Simulations [PDF]

open access: yes, 2008
We combine first-principles density-functional theory with matrix Green’s function calculations to predict the structures and charge transport characteristics of self-assembled monolayers (SAMs) of four classes of systems in contact with Au(111 ...
George, Christopher   +4 more
core   +1 more source

Identification and biosynthesis of a novel xanthomonadin-dialkylresorcinol-hybrid from Azoarcus sp. BH72.

open access: yesPLoS ONE, 2014
A novel xanthomonadin-dialkylresorcinol hybrid named arcuflavin was identified in Azoarcus sp. BH72 by a combination of feeding experiments, HPLC-MS and MALDI-MS and gene clusters encoding the biosynthesis of this non-isoprenoid aryl-polyene containing ...
Tim A Schöner   +3 more
doaj   +1 more source

An Improved and Practical Method for Synthesizing of α-Sanshools and Spilanthol

open access: yesFrontiers in Chemistry, 2020
An efficient and practical route for the synthesis of α-sanshools and spilanthol is described herein. Several modifications of an existing method enabled the preparation of the (2E,6Z,8E,10E)-tetraene precursor of hydroxy-α-sanshool in good yield.
Akira Nakamura   +3 more
doaj   +1 more source

The Effect of varying Ground-state Aromaticity on the First Molecular Electronic Hyperpolarizabilites of Organic Donor-Acceptor Molecules [PDF]

open access: yes, 1993
A series of compounds of the form 4-dimethylaminophenyl–polyene–acceptor, where the polyene ranges from nothing to all-trans-1,3,5-hexatriene and the acceptor is 2-nitrovinyl, formyl, or 2,2-dicyanovinyl has been prepared and their β values measured by ...
Cheng, Lap-Tak   +2 more
core   +1 more source

PH regulation of amphotericin B channels activity in the bilayer lipid membrane [PDF]

open access: yes, 2016
Background: Amphotericin B (AmB) is a polyene antibiotic frequently applied in the treatment of systemic fungal infections in spite of its secondary effects.
Ashrafpour, M.   +2 more
core   +2 more sources

Effect of Post–Polyketide Synthase Modification Groups on Property and Activity of Polyene Macrolides

open access: yesAntibiotics, 2023
The biosynthesis of polyene macrolides, which are natural products produced by soil actinomycetes, have been extensively explored, and recent studies have focused on the effects of post–polyketide synthase (PKS) modifications to polyene macrolides on ...
Liqin Qiao   +3 more
doaj   +1 more source

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

open access: yeseLife, 2015
Sterol traffic between the endoplasmic reticulum (ER) and plasma membrane (PM) is a fundamental cellular process that occurs by a poorly understood non-vesicular mechanism. We identified a novel, evolutionarily diverse family of ER membrane proteins with
Alberto T Gatta   +6 more
doaj   +1 more source

Photoinduced Dynamics of 13,13′-Diphenylpropyl-β-carotene

open access: yesMolecules, 2023
Carotenoids are ubiquitous pigment systems in nature which are relevant to a range of processes, such as photosynthesis, but the detailed influence of substitutions at the polyene backbone on their photophysics is still underexplored.
Sangho Koo   +5 more
doaj   +1 more source

Gombapyrones E and F, New α-Pyrone Polyenes Produced by Streptomyces sp. KMC-002

open access: yesMolecules, 2011
Microorganism-derived polyene polyketides have been shown to display a variety of biological activities and have attracted great interest due to their structurally intriguing chemical diversity.
Kang Ro Lee   +3 more
doaj   +1 more source

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