Results 81 to 90 of about 14,397 (234)
Heronamides G–L, polyene macrolactams from Streptomyces niveus
New polyene macrolactams, heronamides G–L (1–6) from the fermentation broth of Streptomyces niveus.
Huang, Xueshi +19 more
core +1 more source
MODELS OF AMPHOTERICIN MEMBRANE CHANNEL BASED ON CONCERTED INTERMOLECULAR =C-H…O INTERACTIONS [PDF]
To study the possibility for amphotericin to form membrane channel via intermolecular interactions mimicing the association mode of polyene macrolides in crystal structures we have built two channel models in vacuo: amphotericin B octamer and hexamer ...
Lisnyak Yu. V
doaj
HPLC-NMR Chemical Profiling and Dereplication Studies of the Marine Brown Alga,
A chemical profiling/dereplication exercise, involving the use of HPLC-NMR and mass spectrometry in combination with the MarinLit database, was conducted on the crude dichloromethane extract of the southern Australian marine brown alga Cystophora ...
Sylvia Urban, Michael Timmers
doaj +1 more source
ABSTRACT Plant‐based antioxidants are widely incorporated into foods to retard oxidative deterioration and to deliver health‐related benefits. Yet, their in‐product and in vivo performance frequently diverges from predictions based on solution‐phase chemical assays, because matrix interactions, processing history, and host metabolism reshape both ...
Márcio Vargas‐Ramella +6 more
wiley +1 more source
Background Polyene antibiotics are important as antifungal medicines albeit with serious side effects such as nephrotoxicity. Reedsmycin (RDM) A (1), produced by marine-derived Streptomyces youssoufiensis OUC6819, is a non-glycosylated polyene macrolide ...
Tingting Yao +9 more
doaj +1 more source
Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells
Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Brice Beauvais +5 more
wiley +1 more source
Es werde Licht! Licht als Antrieb und Regulator in synthetischen Zellen
Zellen sind Systeme außerhalb des Gleichgewichts, die ihre Eigenschaften in Raum und Zeit regulieren. In biomimetischen synthetischen Zellen bietet Licht eine einzigartige Möglichkeit, Vorgänge räumlich und zeitlich anzutreiben und zu kontrollieren.
Matthew E. Allen +5 more
wiley +1 more source
Polyene antibiotic that inhibits membrane transport proteins
The limited therapeutic arsenal and the increase in reports of fungal resistance to multiple antifungal agents have made fungal infections a major therapeutic challenge.
van Leeuwen, M.R. +4 more
core +1 more source
Mechanically Assisted PO, PN, and PS Bonds Formation
We present a general mechanochemical strategy for constructing PO, PN, and PS bonds via solvent‐free reactions of phosphoryl chlorides with O‐, N‐, and S‐nucleophiles. The method operates under mild conditions, shows broad substrate scope, and affords phosphates, phosphoramidates, and thiophosphates efficiently, providing a sustainable platform for ...
Camilo Morales‐Manrique +4 more
wiley +1 more source
Charge Transport through Polyene Self-Assembled Monolayers from Multiscale Computer Simulations
We combine first-principles density-functional theory with matrix Green’s function calculations to predict the structures and charge transport characteristics of self-assembled monolayers (SAMs) of four classes of systems in contact with Au(111 ...
Kim, Yong-Hoon +4 more
core +2 more sources

