Results 61 to 70 of about 410,512 (273)

Polyethylene Glycol‐Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart

Advanced Science, 2022
Protein therapeutics, except for antibodies, have a short plasma half‐life and poor stability in circulation. Covalent coupling of polyethylene glycol (PEG) to protein drugs addresses this limitation.
Imran Ozer, Garrett Kelly, Renpeng Gu, Xinghai Li, Nikita Zakharov, Parul Sirohi, Smita K. Nair, Joel H. Collier, Michael S. Hershfield, Angus M. Hucknall, Ashutosh Chilkoti   +10 more
doaj   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

Advanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero, Meghna Jha, Elsa Veronica Flores‐Vela, Joost Kimpel, Andreas Schaefer, Jiali Guo, Jesika Asatryan, Alberto Peinador Veiga, Shuichi Haraguchi, Per‐Anders Carlsson, Jaime Martín, Mariano Campoy‐Quiles, Christian Müller   +12 more
wiley   +1 more source

Modelling and analysis of strength and durability properties of internal curing concrete using PEG 400 and artificial neural network

Discover Sustainability
The traditional curing processes necessitate a large amount of water. This is especially difficult in locations where there is a lack of water and for construction of high-rise structures.
Sowjanya Gowdra Virupakshappa, Anadinni Shrishail Basappa, Mahadevaiah Thimmarayappa, Channa Keshava Naik Narayana, Abdulrajak Buradi, Addisu Frinjo Emma   +5 more
doaj   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Characterizations of Cuprous Oxide Thin Films Prepared by Sol-Gel Spin Coating Technique with Different Additives for the Photoelectrochemical Solar Cell

International Journal of Photoenergy, 2014
Cuprous oxide (Cu2O) thin films were deposited onto indium tin oxide (ITO) coated glass substrate by sol-gel spin coating technique using different additives, namely, polyethylene glycol and ethylene glycol.
D. S. C. Halin, I. A. Talib, A. R. Daud, M. A. A. Hamid   +3 more
doaj   +1 more source

Confinement‐Engineered Thermally Programmed Ion‐Gating Separator for Decoupling Thermal–Electrochemical Feedback in High‐Energy Lithium‐Ion Batteries

Advanced Functional Materials, EarlyView.
A new phase‐change material encapsulated membrane offers more thermal resilience stability and safety than the conventional separators for batteries. ABSTRACT Thermal runaway in lithium‐ion batteries arises from the intrinsic coupling between heat generation and ion transport, yet conventional shutdown separators primarily rely on passive pore collapse
Sumedha Rajpoot, Wei‐Nien Su, Sheng‐Chiang Yang, Yu Chun Huang, Wahyu Fiqih Virdiansyah, Ashok Ranjan, Han‐Hsuan Hsieh, Chia‐Lung Hsieh, Yu‐Wei Li, Yosef Nikodimos, Zabish Bilew Muche, Yu Jen Liang, Chia‐Chi Wang, Chih‐Ching Liu, Gao‐Jhih Liang, Chun‐Chen Yang, She‐Huang Wu, Bing Joe Hwang   +17 more
wiley   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Trends in utilization and off-label use of polyethylene glycol 4000 laxatives and the prevalence of constipation in children in France

, 2011
Nawab Qizilbash1,2, Ignacio Mendez11OXON Epidemiology, Madrid, Spain, and London, UK; 2Department of Primary Care and Social Medicine, Imperial College, London University, UKPurpose: To determine trends in utilization and off-label use of polyethylene ...
Nawab Qizilbash, null Méndez, Mendez I, Qizilbash N   +3 more
core   +1 more source

Nanomechanics of confined polymer systems [PDF]

, 2014
Polymers anchored to surfaces play an important role in nature and technology, and regulate diverse interfacial phenomena in areas such as tribology and colloidal stability.
Hyötylä, Janne T.
core   +1 more source

Reversible Tuning of Multiple Molecular Kinking for Stem Cell Regulation In Vivo

Advanced Functional Materials, EarlyView.
In this work, we introduce the novel concept of background component‐free “multiple kinks” material platform composed solely of liganded multiple kink‐bearing molecules as a strategy for dynamic biomaterial design. Tri‐kink molecules enable effective near‐infrared light‐triggered ligand masking and visible light‐triggered ligand exposure, thereby ...
Kanghyeon Kim, Jeongah Shin, Chowon Kim, Honghwan Choi, Dahee Kim, Sungkyu Lee, Choongmo Kang, Hyunsik Hong, Taehoon Ha, Nayeon Kang, Jungyeon Rhi, Ramar Thangam, Yuri Kim, Jeongyun Heo, Cheol Hwan Kwak, Jangsun Hwang, Daun Jeong, Rasoul Moradi, Sunghoon Hur, Hyun‐Cheol Song, Hyun‐Do Jung, Min Jae Lee, Rongqin Huang, Pooyan Makvandi, Yun Suk Huh, Ji Hye Choi, Wenguo Cui, Sehoon Kim, Heemin Kang   +28 more
wiley   +1 more source