Results 81 to 90 of about 161,141 (234)

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

open access: yesAdvanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi   +3 more
wiley   +1 more source

Minimum polyethylene glycol 6000 concentration for selecting Musa spp. in vitro plants tolerant to water stress

open access: yesBiotecnología Vegetal, 2017
Increasingly intense droughts are an abiotic factor which has affected bananas and plantains (Musa spp.) production, therefore it is necessary to obtain tolerant genotypes. Plants in vitro selection offers advantages over field selection as it saves time,
Leonardo J Moreno-Bermúdez   +3 more
doaj  

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

open access: yesAdvanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte   +21 more
wiley   +1 more source

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

open access: yesAdvanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum   +14 more
wiley   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

open access: yesAdvanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot   +3 more
wiley   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

open access: yesAdvanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi   +13 more
wiley   +1 more source

Mechanically Assisted Magnetic Actuation in Ceramic‐Based Microscrolls for Fast and Durable Soft Robotic Systems

open access: yesAdvanced Materials, EarlyView.
Ceramic‐based V2O5/Fe3O4 hybrid films are shaped into butterfly‐proboscis‐inspired microscroll actuators. Magnetic triggering initiates unrolling, while geometry‐programmed elastic strain energy drives rapid recoil, enabling fast, reversible, durable, and load‐bearing actuation under near‐field magnetic stimulation.
Semi Kim   +5 more
wiley   +1 more source

Low Resistance Interphase Formation at the PEO‐LiTFSI|LGPS Interface in Lithium Solid‐State Batteries

open access: yesAdvanced Materials Interfaces, EarlyView.
Interfacial charge transfer and low‐resistance interphase formation between PEO‐based polymer and Li10GeP2S12 solid electrolytes are investigated using multi‐electrode impedance spectroscopy and advanced analytical techniques such as XPS and ToF‐SIMS.
Ujjawal Sigar   +6 more
wiley   +1 more source

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

open access: yesAdvanced Materials Interfaces, EarlyView.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung   +6 more
wiley   +1 more source

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

open access: yesAdvanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy