Results 181 to 190 of about 7,636 (247)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, Volume 38, Issue 61, 2 November 2026.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Antibody‐Precomplexed Hemagglutinin Constructs Multivalently Bind Sialylated Glycan Receptors with Variable Valencies

Advanced Materials Interfaces, Volume 13, Issue 21, 6 November 2026.
Hemagglutinin precomplexation with antibodies (Abs) results in broad valency distributions, though it increases the total avidity from mM to nM to high nM. The valency distribution and the orientation of multivalent HA‐Ab complexes determine the extent of binding to different types of assays, whether the receptors are displayed in 2D or 3D.
Daniel Y. E. L. Tambuwun, María Ríos Carrasco, Elif Uslu, Geert‐Jan P. H. Boons, Nadia J. Mokiem, Albert J. R. Heck, Victor C. Yin, Robert P. de Vries, Jurriaan Huskens   +8 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, Volume 13, Issue 61, 3 November 2026.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

MXenes for Boosting Potassium Ion Storage: Structure‐Property Relationships, Interface Science, Microscopic Mechanisms, and Application Perspectives

Carbon Neutralization, Volume 5, Issue 6, November 2026.
MXene‐based potassium‐ion battery anodes are mapped by linking synthesis, surface chemistry, heterostructure design, and practical evaluation. Pristine MXenes and composites with carbon, oxides, sulfides, selenides, tellurides, and alloying phases are compared, while intercalation, pseudocapacitive, conversion/alloying, built‐in‐field, and trapping ...
Haohao Ding, Lingxia Fan, Lize Zhang, Xinghui Sun, Hongwei Bi, Aruuhan Bayaguud, Yelong Zhang   +6 more
wiley   +1 more source

Carbon‐Based Adsorbents for CO2 Capture: Mechanism‐Guided Material Design and Data‐Driven Optimization

Carbon Neutralization, Volume 5, Issue 6, November 2026.
The main purpose of this review is to summarize recent progress in the broad family of carbon‐based materials and their derivatives for CO2 capture. Rather than focusing on a single precursor or modification route, it examines pristine carbon adsorbents, functionalized carbon derivatives, and carbon‐based composites within a unified framework.
Jinliang Cai, Jianchao Zhang, Zhiyong Peng, Yihe Miao, Jialing Xu   +4 more
wiley   +1 more source

M11‐CAR T cells inhibit murine cytomegalovirus in vitro upon recognition of virion‐ and cell‐associated glycoprotein B

Clinical &Translational Immunology, Volume 15, Issue 11, 2026.
Abstract Objectives Viral infections are predominantly managed with conventional antiviral drugs, which, despite their efficacy, can cause toxicity and promote resistance. Cell‐based immunotherapies offer an alternative, but cytomegaloviruses (CMV) profoundly interfere with MHC class I antigen presentation, thereby impairing conventional virus‐specific
Sabrina Kübel, Christopher Garçon, Hanna Menschikowski, Arne Cordsmeier, Jens‐Christian Albrecht, Friederike Oltmanns, Larissa Bauer, Manuel Hermann, Kristina Holdt, Heinrich Sticht, Marco Thomas, Thomas H Winkler, Brigitte Scholz, Doris Jungnickl, Armin Ensser   +14 more
wiley   +1 more source

Air Stability of Sulfide Solid Electrolytes: From Theoretical Insights to Practical Solutions

ENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 6, November 2026.
This paper reviews research progress on the air stability of SSEs, covering their instability mechanisms and modification strategies, while outlining core challenges and future directions for practical applications. Sulfide solid electrolytes are pivotal for enabling high‐performance all‐solid‐state batteries due to their high ionic conductivity and ...
Hongbing Ding, Yue Hu, Xin Li, Yang Su, Xinlu Wang, Hongbo Zhang, Guixia Liu, Wensheng Yu, Xiangting Dong, Jinxian Wang, Xin Wang   +10 more
wiley   +1 more source

Primary Cell‐Based Lymphatic Spheroids in Synthetic PEG Hydrogels: A Scalable Model of Lymphatic Sprouting

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 11, November 2026.
Primary lymphatic endothelial cells, lymphatic muscle cells, and human dermal fibroblasts self‐assemble into spheroids within defined, tunable PEG‐4MAL hydrogels, creating a bottom‐up sprouting assay. Rat collecting‐vessel spheroid sprouting peaks at intermediate stiffness (8% and 10% PEG‐4MAL), is rescued at low stiffness by VEGF‐C, and is suppressed ...
Yarelis Gonzalez‐Vargas, Greta Hiehle, Saiid Parker, Nishone Thompson, Maya E. Leveille, Alan Liu, Zhanna Nepiyushchikh, J. Brandon Dixon   +7 more
wiley   +1 more source

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

MedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang, Qifei Pan, Wenjuan Long, Xinyao Li, Jianqin Mao, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Mingqin Shi, Yang Zhou, Jiarong Du, Zhongyang Hu, Xiaoman Lv, Yishu Chen, Dongdong Qin   +15 more
wiley   +1 more source

Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Graphical overview of targeted protein degradation: mechanisms, molecular determinants, delivery strategies, and therapeutic development. This graphical abstract summarizes the major degradation pathways involved in targeted protein degradation, including the ubiquitin–proteasome system, endocytosis–lysosome pathway, and autophagy‐dependent degradation.
Huaijuan Guo, Haishuang Duan, Yang Liu, Kelan Fang, Lujia Xiao, Ling Bai, Xiao Qu, Xuebing Yan, Kun Zhang   +8 more
wiley   +1 more source