Results 81 to 90 of about 7,636 (247)

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing   +9 more
wiley   +1 more source

Mannosylated biodegradable polyethyleneimine for targeted DNA delivery to dendritic cells

open access: yes, 2012
Xun Sun, Simu Chen, Jianfeng Han, Zhirong ZhangKey Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, People’s Republic of ChinaBackground: To establish a ...
Zhang Z, Han J, Sun X, Chen S
core  

Electrochemically deposited polyethyleneimine films and their characterization [PDF]

open access: yes, 2010
Polyethyleneimine films have been deposited on platinum electrode surfaces by electrochemical oxidation of ethylenediamine H2N–CH2–CH2–NH2 (EDA) in acetonitrile solutions.
G. Herlem   +20 more
core   +1 more source

Immunomagnetic‐MXene Bifunctional Probes for Ultrasensitive and Specific Terahertz Metasensing of Tumor‐Derived Exosomes

open access: yesAdvanced Science, EarlyView.
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin   +8 more
wiley   +1 more source

A Dual‐Functional Nanoplatform Targeting the dsDNA–cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation

open access: yesAdvanced Science, EarlyView.
RU@PEI‐ZIF integrates dsDNA scavenging with local cGAS inhibition to suppress the dsDNA–cGAS–STING/Netrin‐1 axis in intervertebral disc degeneration. By attenuating nucleus pulposus cell senescence, inflammatory and matrix‐catabolic responses, and pathological sensory innervation, this dual‐functional nanoplatform preserves disc integrity and reduces ...
Zhaojun He   +12 more
wiley   +1 more source

Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion

open access: yesAdvanced Science, EarlyView.
Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping   +4 more
wiley   +1 more source

The Presence of Polysaccharides, Glycerol, and Polyethyleneimine in Hydrogel Enhances the Performance of the Glucose Biosensor

open access: yesBiosensors, 2019
The use of amperometric biosensors has attracted particular attention in recent years, both from researchers and from companies, as they have proven to be low-cost, reliable, and very sensitive devices, with a wide range of uses in different matrices ...
Marco Fois   +6 more
doaj   +1 more source

Shaped Silica-polyethyleneimine Composite Sorbents for CO2 Capture via Adsorption

open access: yes, 2017
Shaped Silica-polyethyleneimine Composite Sorbents for CO2 Capture via ...
AL Chaffee (14881387)   +1 more
core  

Reln mRNA Delivery Drives Neurogenic Bone Regeneration by Orchestrating Schwann Cell‐Mediated Exosomal Trafficking

open access: yesAdvanced Science, EarlyView.
MSNs serve as a robust vehicle for CRISPRa‐mediated Reln induction, driving bone repair through the establishment of a neurogenic‐supportive microenvironment. ABSTRACT Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, while the mechanisms and new strategies underlying neurogenic bone regeneration ...
Shuai Lin   +9 more
wiley   +1 more source

Complexation of alginate with linear and branched polyethyleneimine

open access: yesJournal of Colloid and Interface Science
This study investigates the complexation behavior of alginate (ALG), a naturally occurring anionic polysaccharide, with two different molecular architectures of synthetic cationic polyethyleneimine (PEI): linear (l-PEI) and branched (b-PEI). While PEI/ALG interactions have been studied for various biomedical and industrial applications, a quantitative ...
Vakeri, Asna   +7 more
openaire   +2 more sources

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