Results 131 to 140 of about 65,839 (347)

The many roads to psychosis: recent advances in understanding risk and mechanisms. [PDF]

, 2018
Schizophrenia is a chronic and severe mental illness which frequently leads to substantial lifelong disability. The past five years have seen major progress in our understanding of the complex genetic architecture of this disorder.
Bearden, Carrie E, Forsyth, Jennifer K
core  

Genetic influences on suicide attempt in adolescence: Evaluating mediation by impulsivity and painful and provocative events

JCPP Advances, EarlyView.
Impulsivity and exposure to painful and provocative events each contribute to risk for suicide attempt. However, there is little support for the hypothesis that genetic influences on suicide attempt are mediated by impulsivity and painful and provocative event exposure in early adolescence.
Mallory Stephenson, Séverine Lannoy, Alexis C. Edwards   +2 more
wiley   +1 more source

The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information

NeuroImage: Clinical, 2016
Genome-wise association studies have identified a number of common single-nucleotide polymorphisms (SNPs), each of small effect, associated with risk to bipolar disorder (BD).
Danai Dima, Simone de Jong, Gerome Breen, Sophia Frangou   +3 more
doaj   +1 more source

Breast cancer polygenic risk scores derived in White European populations are not calibrated for women of Ashkenazi Jewish descent

, 2023
Eleanor Roberts, Elke M. van Veen, Helen L. Byers, Ofra Barnett‐Griness, Naomi Gronich, Flavio Lejbkowicz, Mila Pinchev, Miriam J. Smith, Anthony Howell, William G. Newman, Emma R. Woodward, Elaine F. Harkness, Adam R. Brentnall, Jack Cuzick, Gad Rennert, Sacha J. Howell, D. Gareth Evans   +16 more
openalex   +1 more source

Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2‐ and 5‐month‐old infants: A longitudinal twin study

JCPP Advances, EarlyView.
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson, Ashraf Yahia, Mark J. Taylor, Angelica Ronald, Kristiina Tammimies, Terje Falck‐Ytter   +5 more
wiley   +1 more source

Sparse whole-genome sequencing identifies two loci for major depressive disorder. [PDF]

, 2015
Major depressive disorder (MDD), one of the most frequently encountered forms of mental illness and a leading cause of disability worldwide, poses a major challenge to genetic analysis.
CONVERGE consortium
core   +1 more source

Differential impacts of parental attention deficit/hyperactivity disorder on early maternal‐infant attachment

JCPP Advances, EarlyView.
Abstract Background Parental attention deficit/hyperactivity disorder (ADHD) is associated with increased postpartum depressive symptoms and impaired daily functioning, potentially impacting early maternal‐infant attachment (MIA). Methods 78 mothers, half with ADHD, were enrolled during pregnancy or postpartum.
Elyse Mark, Brooke S. G. Molina, Michelle A. Wilson, Charles H. Zeanah, Heather M. Joseph   +4 more
wiley   +1 more source

Development of a Polygenic Risk Score for BMI to Assess the Genetic Susceptibility to Obesity and Related Diseases in the Korean Population [PDF]

, 2023
Nara Yoon, Yoon Shin Cho
openalex   +1 more source

Rare variant polygenic risk score

, 2023
Rare variant polygenic risk ...
openaire   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

JCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki, Isabelle Ouellet‐Morin, Helena M. S. Zavos, Sylvana Côté, Richard E. Tremblay, Jean‐Philippe Gouin, Massimiliano Orri, Michel Boivin, Marie‐Claude Geoffroy   +8 more
wiley   +1 more source