Results 231 to 240 of about 65,839 (347)

Supplemental Table 4 from Breast Cancer Polygenic Risk Score Associated with Outcomes after <i>In Situ</i> Breast Disease

Jasmine Timbres, Kelly Kohut, Nasim Mavaddat, Douglas F. Easton, Christos Petridis, Rebecca Roylance, Marjanka K. Schmidt, Elinor J. Sawyer   +7 more
openalex   +1 more source

Association of clonal haematopoiesis and diabetes with outcomes after autologous haematopoietic cell transplantation

Diabetes, Obesity and Metabolism, EarlyView.
Rusha Bhandari, June‐Wha Rhee, Sitong Chen, Raju Pillai, Alysia Bosworth, Artem Oganesyan, Liezl Atencio, Caitlyn Estrada, Mareen Kassabian, Lanie Lindenfeld, Scott Goldsmith, Michael Rosenzweig, Alex F. Herrera, Matthew G. Mei, Ryotaro Nakamura, Rama Natarajan, F. Lennie Wong, Stephen J. Forman, Saro H. Armenian   +18 more
wiley   +1 more source

Global Patterns of Comorbidities Among Patients With Hidradenitis Suppurativa: A Systematic Review and Meta‐Analysis

International Journal of Dermatology, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder increasingly recognized as a systemic disease with diverse comorbidities. While several comorbid conditions are well documented, regional differences in prevalence remain unclear.
Aditya K. Gupta, Amanda Liddy, Vasiliki Economopoulos, Renata Magalhaes   +3 more
wiley   +1 more source

Risk score roulette: A cautionary tale of polygenic risk score reliability. [PDF]

J Alzheimers Dis
Xue D, Blue EE, Wood AC, Rotter JI, Fohner AE.   +4 more
europepmc   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

STREAM-PRS: a multi-tool pipeline for streamlining polygenic risk score computation. [PDF]

Genome Med
Becelaere S, Abakkouy Y, Jans DS, David M, Vermeire S, Cleynen I.   +5 more
europepmc   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Polygenic Risk Score Associated with Gestational Diabetes Mellitus in an AmericanIndian Population. [PDF]

J Pers Med
Peterson K, Powe CE, Sun Q, Azure C, Azure T, Davis H, Gourneau K, LaRocque S, Poitra C, Poitra S, Standish S, Parisien TJ, Morin KJ, Best LG.   +13 more
europepmc   +1 more source

Data Sheet 1_Development and validation of a polygenic risk score for height in a Greek cohort: Association with blood pressure measurements.docx

Ioanna Panagiota Kalafati (21225470), Margaritis Tsifintaris (11605543), Maria Dimitriou (160853), Effimia Grigoriou (21225473), Panagiotis Moulos (2818735), George V. Dedoussis (7726121)   +5 more
openalex   +1 more source

Unravelling Twin Births in German Holstein Cows: Phenotypic Associations, Genetic Analysis and Potential Underlying Genes and Hormones

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Twin births in dairy cattle are rare but present significant challenges for animal welfare, as both the health of the cow and the calves are affected. This causes economic losses, which prompts breeders to select against twin births and identify associated risk factors.
Laura Hüneke, Hatem Alkhoder, Dierck Segelke, Georg Thaller, Christin Schmidtmann   +4 more
wiley   +1 more source