Results 161 to 170 of about 40,214 (287)

Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family

Andrology, EarlyView.
Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni, Frank Tüttelmann, Livio Casarini   +2 more
wiley   +1 more source

Genetic and Phenotypic Associations of the Polygenic Score of Delay Discounting and Life History Traits. [PDF]

Am J Hum Biol
Fieder M, Huber S.
europepmc   +1 more source

Genetic Correlates of Treatment-Resistant Depression: Insights from Polygenic Scores Across Cognitive, Temperamental, and Sleep Traits in the All of US cohort [PDF]

Bohan Xu, Katherine L. Forthman, Rayus Kuplicki, Jonathan Ahern, Robert Loughnan, Firas Naber, Wesley K. Thompson, Charles B. Nemeroff, Martin P. Paulus, Chun Chieh Fan   +9 more
openalex   +1 more source

Advances in the genetics of refractive errors: Contributions from the CREAM consortium

Acta Ophthalmologica, EarlyView.
Abstract The Consortium for Refractive Error and Myopia (CREAM) was established in 2011, bringing together an international team of researchers studying more than 30 cohorts. Since its establishment, CREAM has played a pivotal role in research investigating the genetics of myopia and other refractive errors, serving as a key driver of progress in the ...
Sze Wai Rosa Li, Xi He, Louise Terry, Virginie J. M. Verhoeven, Samantha Sze‐Yee Lee, Gareth Lingham, Jeremy A. Guggenheim, David A. Mackey, Seang‐Mei Saw, Caroline C. W. Klaver, Chi Pui Pang, CREAM Consortium   +11 more
wiley   +1 more source

Blood Pressure Polygenic Score Predicts Long-Term Blood Pressure Control and Treatment-Resistant Hypertension. [PDF]

Hypertension
Cho SMJ, Ruan Y, Lee HH, Koyama S, Juraschek SP, Allen NB, Yang E, McEvoy JW, Secemsky E, Honigberg MC, Fahed AC, Patel A, Hornsby WE, Natarajan P.   +13 more
europepmc   +1 more source

The Alpha‐1 Pi*MZ Genotype Is an Independent Risk Factor for Hepatocellular Carcinoma Development in Patients With ACLD

Alimentary Pharmacology &Therapeutics, EarlyView.
Alpha‐1 antitrypsin deficiency is a genetic disease that affects the lungs and the liver. The role of the heterozygous genetic defect in the development of liver cancer in patients with cirrhosis is unclear. Our study found that carrying the Pi*MZ genotype increases the risk of developing liver cancer.
Lorenz Balcar, Georg Semmler, Bernhard Scheiner, Rafael Paternostro, Benedikt Simbrunner, Tina Jasmin Haunold, Mathias Jachs, Lukas Hartl, Benedikt Silvester Hofer, Nina Dominik, Michael Schwarz, Georg Kramer, Christian Sebesta, Paul Thöne, Matthias Pinter, Michael Trauner, Thomas Reiberger, Albert Friedrich Stättermayer, Mattias Mandorfer   +18 more
wiley   +1 more source

S4-multi: Enhancing polygenic score prediction in ancestrally diverse populations. [PDF]

HGG Adv
Baierl J, Tyrer JP, Lai PH, Gayther SA, Hsiao YW, Jones M, Pharoah PDP, Peng PC.   +7 more
europepmc   +1 more source

Correction: Power and Predictive Accuracy of Polygenic Risk Scores

, 2013
Frank Dudbridge
openalex   +2 more sources

Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort

, 2022
Chris Lauber, Mathias J. Gerl, Christian Klose, Filip Ottosson, Olle Melander, Kai Simons   +5 more
openalex   +2 more sources

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease [PDF]

, 2020
Joshua Elliott, Barbara Bodinier, Tom A. Bond, Marc Chadeau‐Hyam, Εvangelos Εvangelou, Karel G.M. Moons, Abbas Dehghan, David C. Muller, Paul Elliott, Ioanna Tzoulaki   +9 more
openalex   +1 more source