Results 211 to 220 of about 1,650,847 (244)

Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project. [PDF]

Cancers (Basel)
Yang X, Usher-Smith JA, Blackmore KM, Brooks JD, Bell KA, Carver T, Chang A, Chiquette J, Easton DF, Eisen A, Eloy L, Fienberg S, Joly Y, Kim RH, Knoppers BM, Lambert-Côté L, Nabi H, Pashayan N, Soucy P, Stockley TL, Turgeon A, Walker MJ, Wolfson M, Dorval M, Chiarelli AM, Antoniou AC, Simard J.   +26 more
europepmc   +1 more source

Chronic alanine aminotransferase elevation in people with HIV: Time trends over 22 years and genetic predisposition

HIV Medicine, EarlyView.
Abstract Introduction Chronic elevation of alanine aminotransferase (cALT) is common in people with HIV. Published reports on cALT prevalence time trends have not been uniform. It is unknown whether genetic background is associated with cALT in people with HIV. Methods cALT was defined as ALT levels (male, >50 U/L, female, >35 U/L) at ≥2 consecutive, 6‐
Noemi R. Simon, Carlotta Mondoka, Christian W. Thorball, Isabella C. Schoepf, Lene Ryom, Irene Abela, Charles Béguelin, Urs Führer, Helen Kovari, Catia Marzolini, Annalisa Marinosci, Christian Kahlert, Luigia Elzi, David Haerry, Matthias Cavassini, Bruno Ledergerber, Jacques Fellay, Gilles Wandeler, Philip E. Tarr, the Swiss HIV Cohort Study, IA Abela, K Aebi‐Popp, A Anagnostopoulos, E Bernasconi, A Boyd, DL Braun, HC Bucher, A Calmy, M Cavassini, SE Chaudron, A Ciuffi, G Dollenmaier, M Egger, L Elzi, JS Fehr, J Fellay, S Frigerio Malossa, CA Fux, HF Günthard, A Hachfeld, DHU Haerry, B Hasse, M Hoffmann, M Huber, D Jackson‐Perry, CR Kahlert, D Kaufmann, O Keiser, RD Kouyos, H Kovari, K Kusejko, ND Labhardt, K Leuzinger, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, M Perreau, A Rauch, LP Salazar‐Vizcaya, P Schmid, O Segeral, RF Speck, M Stöckle, B Surial, PE Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly   +72 more
wiley   +1 more source

Polygenic Score Approach to Predicting Risk of Metabolic Syndrome. [PDF]

Genes (Basel)
Timasheva Y, Kochetova O, Balkhiyarova Z, Korytina G, Prokopenko I, Nouwen A.   +5 more
europepmc   +1 more source

Nevus Counts, Sun Exposure and Phenotypic Characteristics in Invasive Versus In Situ Non‐Lentigo Maligna/Non‐Acral Lentiginous Melanoma

International Journal of Dermatology, EarlyView.
In a retrospective study in 3026 Southern European melanoma patients, higher nevus counts and severe sunburn history were associated with lower odds of invasive superficial spreading melanoma versus non‐lentigo maligna/non‐acral lentiginous melanoma in situ.
Clio Dessinioti, Ruggero Moro, Mihaella Plaka, Ioannis A. Stratigos, Celia Requena, Katerina Kypreou, Victor Traves, Irene Stefanaki, Eduardo Nagore   +8 more
wiley   +1 more source

The association between temperament and polygenic score for psychopathology from infancy to middle childhood. [PDF]

J Child Psychol Psychiatry
Freitag E, Kelsey C, de Mendonça Filho EJ, Pokhvisneva I, Patel S, Silveira PP, Bosquet Enlow M, Nelson CA.   +7 more
europepmc   +1 more source

The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

International Journal of Immunogenetics, EarlyView.
ABSTRACT Genetic factors that modulate immune regulation are increasingly recognised as contributors to the heterogeneity and clinical course of autoimmune diseases. Polymorphisms of protein tyrosine phosphatase non‐receptor type 22 (PTPN22) are associated with several autoimmune diseases.
Sonja Kvist, Johanna Teräsjärvi, Heidi Rahikkala, Jussi Mertsola, Milja Möttönen, Qiushui He   +5 more
wiley   +1 more source

Differential Performance of Polygenic Score for Coronary Artery Disease Based on Coronary Artery Calcium Between Men Living With and Without HIV. [PDF]

J Am Heart Assoc
Wojcik G, Arvanitis M, Haberlen S, Kim EY, Kim H, Nam K, Feinstein MJ, Wolinsky S, Margolick JB, Budoff M, Magnani JW, Duggal P, Post WS.   +12 more
europepmc   +1 more source

The association between GLP-1R expression and cardiovascular-kidney-metabolic-related diseases in non-diabetic and non-obese population: evidence triangulation using Mendelian randomization, observational and polygenic score association analysis. [PDF]

BMC Med
Chen Z, Yang Q, Liu J, Zhao H, Ying H, Liu H, Huang L, Lin H, Wang S, Li M, Sun Y, Wang T, Zhao Z, Xu M, Chen Y, Xu Y, Lu J, Ning G, Gu Y, Wang W, Li J, Bi Y, Zheng J.   +22 more
europepmc   +1 more source

Rare-Variant Genome-Wide Association and Polygenic Score Assessment of Vitamin D Status in a Middle Eastern Population. [PDF]

Int J Mol Sci
Hendi NN, Umlai UK, Albagha O, Nemer G.
europepmc   +1 more source

Polygenic score from MODY genes is associated with type 1 diabetes and disease characteristics. [PDF]

Acta Diabetol
Catamo E, Conti A, Franceschi R, Dovc K, Morosini C, Tinti D, Aldegheri L, Cappellani S, Tamaro G, Zanfardino A, Faleschini E, Rabbone I, Bonfanti R, Battelino T, Iafusco D, Tornese G, Robino A.   +16 more
europepmc   +1 more source