Results 21 to 30 of about 423 (152)

Chemical Diversity and Biosynthesis of Drimane‐Type Sesquiterpenes in the Fungal Kingdom

open access: yesChemBioChem, Volume 23, Issue 17, September 5, 2022., 2022
Fungal drimane‐type sesquiterpenes (DTSs) are emerging as a very interesting class of chemicals with many notable activities. Elucidation of DTS biosynthesis in fungi revealed that the two main precursors, drimenol and drim‐8‐ene‐11‐ol, are the preferred backbones.
Ying Huang, Vito Valiante
wiley   +1 more source

Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity

open access: yesMemorias do Instituto Oswaldo Cruz, 2013
This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and ...
Vanessa Duarte Claudino   +8 more
doaj   +1 more source

Safety and Efficacy of Medicinal Plants Used to Manufacture Herbal Products with Regulatory Approval in Uganda: A Cross‐Sectional Study

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Introduction. The Uganda National Drug Authority requires phytochemical screening, freedom from microbial contamination, and evidence of safety and efficacy of the constituent plants to register herbal products. Since Uganda has no pharmacopeia, safety, efficacy, and plant processing information are not readily available.
Bruhan Kaggwa   +11 more
wiley   +1 more source

Effect of Polygodial on the Mitochondrial ATPase of Saccharomyces cerevisiae [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2000
ABSTRACT The fungicidal mechanism of a naturally occurring sesquiterpene dialdehyde, polygodial, was investigated in Saccharomyces cerevisiae . In an acidification assay, polygodial completely suppressed the glucose-induced decrease in external pH at 3.13 μg/ml, the same as the fungicidal concentration ...
C S, Lunde, I, Kubo
openaire   +2 more sources

Anthelmintic Agents from African Medicinal Plants: Review and Prospects

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Soil‐transmitted helminthiasis affects more than 1.5 billion people globally and largely remains a sanitary problem in Africa. These infections place a huge economic burden on poor countries and affect livestock production, causing substantial economic losses and poor animal health. The emergence of anthelmintic resistance, especially in livestock, and
Jonathan Jato   +10 more
wiley   +1 more source

Conventional Medicinal Uses, Phytoconstituents, and Biological Activities of Euphorbia officinarum L.: A Systematic Review

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, Volume 2022, Issue 1, 2022., 2022
The Moroccan endemic plant Euphorbia officinarum is a traditional medicinal plant, known locally as “Daghmus.” Plants in the genus Euphorbia are well known for the chemical diversity of their diterpenoids and isoprenoid constituents, which perform many activities such as cytotoxic, antimicrobial, and anti‐inflammatory activities, as well as different ...
Imane Chamkhi   +3 more
wiley   +1 more source

Study on the Cytotoxic Activity of Drimane Sesquiterpenes and Nordrimane Compounds against Cancer Cell Lines

open access: yesMolecules, 2014
Twelve drimanes, including polygodial (1), isopolygodial (2), drimenol (3), confertifolin (4), and isodrimenin (5), were obtained from natural sources.
Ivan Montenegro   +9 more
doaj   +1 more source

Chemical and Cytotoxic Activity of three main Sesquiterpenoids from Warburgia ugandensis

open access: yesResults in Chemistry, 2021
Plant materials of Warburgia ugandensis have long been used in traditional African medicine due to their broad spectrum of biological activity. Here, we describe an efficient and mild isolation of three major compounds polygodial 1a, warburganal 2a, and ...
Reni Kitte   +8 more
doaj   +1 more source

Antifeedant Activity of Some Polygodial Derivatives

open access: yesZeitschrift für Naturforschung C, 2008
Polygodial (1) and its derivatives acetal 2 (propylene) and 3 (ethylene) were prepared and their antifeedant activity and toxic effects evaluated on several insect species with different feeding ecologies (Spodoptera littoralis, Leptinotarsa decemlineata, Myzus persicae and Rhopalosiphum padi) along with that of polygonone (4).
Moreno Osorio, Luis Eduardo   +4 more
openaire   +4 more sources

Mechanism of Action against Food Spoilage Yeasts and Bioactivity of Tasmannia lanceolata, Backhousia citriodora and Syzygium anisatum Plant Solvent Extracts

open access: yesFoods, 2018
Bioactive properties of solvent extracts of Tasmannia lanceolata, Backhousia citriodora and Syzygium anisatum investigated. The antimicrobial activities evaluated using agar disc diffusion method against two bacteria (Escherichia coli and Staphylococcus ...
Fahad Alderees   +4 more
doaj   +1 more source

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