Results 21 to 30 of about 444 (156)
Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in Saccharomyces cerevisiae. [PDF]
Polygodial is a “hot” peppery-tasting sesquiterpenoid that was first described for its anti-feedant activity against African armyworms. Using the haploid deletion mutant library of Saccharomyces cerevisiae, a genome-wide mutant screen was performed to shed more light on polygodial’s antifungal mechanism of action. We identified 66 deletion strains that
Kipanga PN +9 more
europepmc +5 more sources
The potential of small molecule natural products and biodegradable lipopeptides to deactivate the different life stages of aggressive Phytophthora species has been demonstrated. Abstract Phytophthora species are a genus in the oomycete class and are destructive plant pathogens.
Gayan H. De Zoysa +3 more
wiley +1 more source
Nanoemulsions formulated from the of essential oils of Tasmannia lanceolata, Backhousia citriodora and Syzygium anisatum have strong antimicrobial activity against bacteria and fungi. Abstract Oil‐in‐water nanoemulsions were formulated using sunflower oil mixed with each of the essential oils of Tasmannia lanceolata (Tasmanian pepper leaf [TPL ...
Fahad Alderees +3 more
wiley +1 more source
Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity
This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and ...
Vanessa Duarte Claudino +8 more
doaj +1 more source
Chemical Diversity and Biosynthesis of Drimane‐Type Sesquiterpenes in the Fungal Kingdom
Fungal drimane‐type sesquiterpenes (DTSs) are emerging as a very interesting class of chemicals with many notable activities. Elucidation of DTS biosynthesis in fungi revealed that the two main precursors, drimenol and drim‐8‐ene‐11‐ol, are the preferred backbones.
Ying Huang, Vito Valiante
wiley +1 more source
Introduction. The Uganda National Drug Authority requires phytochemical screening, freedom from microbial contamination, and evidence of safety and efficacy of the constituent plants to register herbal products. Since Uganda has no pharmacopeia, safety, efficacy, and plant processing information are not readily available.
Bruhan Kaggwa +11 more
wiley +1 more source
Twelve drimanes, including polygodial (1), isopolygodial (2), drimenol (3), confertifolin (4), and isodrimenin (5), were obtained from natural sources.
Ivan Montenegro +9 more
doaj +1 more source
Antifeedant Activity of Some Polygodial Derivatives
Polygodial (1) and its derivatives acetal 2 (propylene) and 3 (ethylene) were prepared and their antifeedant activity and toxic effects evaluated on several insect species with different feeding ecologies (Spodoptera littoralis, Leptinotarsa decemlineata, Myzus persicae and Rhopalosiphum padi) along with that of polygonone (4).
Moreno Osorio, Luis Eduardo +4 more
openaire +4 more sources
Chemical and Cytotoxic Activity of three main Sesquiterpenoids from Warburgia ugandensis
Plant materials of Warburgia ugandensis have long been used in traditional African medicine due to their broad spectrum of biological activity. Here, we describe an efficient and mild isolation of three major compounds polygodial 1a, warburganal 2a, and ...
Reni Kitte +8 more
doaj +1 more source
Bioactive properties of solvent extracts of Tasmannia lanceolata, Backhousia citriodora and Syzygium anisatum investigated. The antimicrobial activities evaluated using agar disc diffusion method against two bacteria (Escherichia coli and Staphylococcus ...
Fahad Alderees +4 more
doaj +1 more source

