Results 1 to 10 of about 639 (142)

Inhibitory Potential of the Drimane Sesquiterpenoids Isotadeonal and Polygodial in the NF-kB Pathway [PDF]

Molecules
Inflammation contributes to the onset and development of many diseases, including neurodegenerative diseases, caused by the activation of microglia, leading to neurological deterioration. Nuclear factor-κB (NF-κB) is one of the most relevant pathways for
Jaime R Cabrera-Pardo, Bernd Schmidt, Cristian Paz   +2 more
exaly   +6 more sources

Investigating the Efficacy of Tasmannia lanceolata Extract in Inactivating Fungi and Prolonging the Shelf Life of Date Fruit [PDF]

Foods, 2022
Date palm (Phoenix dactylifera L.) is one of the world’s oldest cultivated plants. Post-harvest losses of date palm due to fungal contamination reached up to 50% of the total production.
Fahad Al-Asmari, Saleha Akter, Ram Mereddy, Yasmina Sultanbawa   +3 more
doaj   +2 more sources

Neuronal ion channel modulation by Drimys winteri compounds: Opening a new chemical space to neuropharmacology [PDF]

Neural Regeneration Research
Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction, which depend on the function of ion channels.
Macarena E. Meza, Oscar Ramirez-Molina, Oscar Flores, Katherine Fariña-Oliva, Pamela A. Godoy, Jorge Fuentealba, Gonzalo E. Yévenes   +6 more
doaj   +2 more sources

A re‐innervated in vitro skin model of non‐histaminergic itch and skin neurogenic inflammation: PAR2‐, TRPV1‐ and TRPA1‐agonist induced functionality [PDF]

Skin Health and Disease, 2021
Background Skin, and epidermis, is innervated by sensory nerve fibres. Interactions between them and signal transduction are only partially elucidated in physiological/pathological conditions, especially in pruritus.
N. Lebonvallet, J. W. Fluhr, C. Le Gall‐Ianotto, R. Leschiera, M. Talagas, A. Reux, A. Bataille, C. Brun, T. Oddos, J.‐P. Pennec, J.‐L. Carré, L. Misery   +11 more
doaj   +2 more sources

In Vitro and In Vivo Evaluation of the Antischistosomal Activity of Polygodial and 9-Deoxymuzigadial Isolated from Drimys brasiliensis Branches [PDF]

Molecules
In the present study, the hexane extract from branches of Drimys brasiliensis (Winteraceae) displayed potent activity against Schistosoma mansoni parasites (100% mortality of the worms at 200 μg/mL). Bioactivity-guided fractionation afforded, in addition
Eric Umehara, Rayssa A. Cajas, Gabriel B. Conceição, Guilherme M. Antar, Adriano D. Andricopulo, Josué de Moraes, João Henrique G. Lago   +6 more
doaj   +2 more sources

Antimicrobial Activity of Drimanic Sesquiterpene Compounds from Drimys winteri against Multiresistant Microorganisms [PDF]

Molecules
In this work, a group of ten sesquiterpene drimanes, including polygodial (1), isopolygodial (2), and drimenol (3) obtained from the bark of Drimys winteri F. and seven synthetic derivatives, were tested in vitro against a unique panel of bacteria, fungi,
Iván Montenegro, Rolando Pazmiño, Ileana Araque, Alejandro Madrid, Ximena Besoain, Enrique Werner, Luis Espinoza-Catalán, Andrés F. Olea, Claudio Parra, Valentina Navarrete Molina, Patricio Godoy, Yusser Olguín, Mauricio A. Cuellar   +12 more
doaj   +2 more sources

Assessment of Phytochemical Composition and Antifungal Activity of Micropropagated Drymis winteri Plants [PDF]

Plants
The search for sustainable alternatives to synthetic agrochemicals has fueled a growing interest in plant-derived bioactive compounds. Drimys winteri (canelo), a native Chilean tree of significant ethnobotanical importance, is a promising source of ...
Julia Rubio, Christian Robles-Kelly, Evelyn Silva-Moreno, Héctor Carrasco, Andrés F. Olea   +4 more
doaj   +2 more sources

Application of the herbal chemical marker ranking system (Herb MaRS) to the standardization of herbal raw materials: a case study [PDF]

BMC Complementary Medicine and Therapies, 2023
Introduction Phytochemical standardization of herbal materials involves establishing consistent levels of one or more active ingredients or markers. It ensures the authenticity and quality of herbal materials, extracts, and their products.
Bruhan Kaggwa, Godwin Anywar, Edson Ireeta Munanura, Raphael Wangalwa, Henry Kyeyune, Hedmon Okella, Fadhiru Pakoyo Kamba, Ogwang Patrick Engeu   +7 more
doaj   +2 more sources

Antibacterial and Antifungal Terpenes from the Medicinal Angiosperms of Asia and the Pacific: Haystacks and Gold Needles [PDF]

Molecules, 2023
This review identifies terpenes isolated from the medicinal Angiosperms of Asia and the Pacific with antibacterial and/or antifungal activities and analyses their distribution, molecular mass, solubility, and modes of action. All data in this review were
Christophe Wiart, Geethanjali Kathirvalu, Chandramathi Samudi Raju, Veeranoot Nissapatorn, Mohammed Rahmatullah, Alok K. Paul, Mogana Rajagopal, Jaya Seelan Sathiya Seelan, Nor Azizun Rusdi, Scholastica Lanting, Mazdida Sulaiman   +10 more
doaj   +2 more sources

Botanical Control of Citrus Green Mold and Peach Brown Rot on Fruits Assays Using a Persicaria acuminata Phytochemically Characterized Extract [PDF]

Plants, 2021
Persicaria acuminata (Polygonaceae) is a perennial herb that grows in the central area of Argentina and it is commonly used by native populations to heal infected wounds and other conditions related to fungal infections.
Melina G. Di Liberto, Gisela M. Seimandi, Laura N. Fernández, Verónica E. Ruiz, Laura A. Svetaz, Marcos G. Derita   +5 more
doaj   +2 more sources