Results 31 to 40 of about 1,539 (210)

Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity

Memorias do Instituto Oswaldo Cruz, 2013
This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and ...
Vanessa Duarte Claudino, Kesia Caroline da Silva, Valdir Cechinel Filho, Rosendo Augusto Yunes, Franco Delle Monache, Alberto Giménez, Efrain Salamanca, David Gutierrez-Yapu, Angela Malheiros   +8 more
doaj   +1 more source

Medicinal Plants of Chile: Evaluation of their Anti-Trypanosoma cruzi Activity [PDF]

, 2013
San Martin, J (San Martin, Jose). Univ Talca, Inst Biol Vegetal & Biotecnol, Talca, ChileThe extracts of several plants of Central Chile exhibited anti-Trypanosoma cruzi trypomastigotes activity.
Christen, P., Ferreira, J., Kemmerling, U., Lopez-Munoz, R., Maya, J.D., Morello, A., Munoz, O.M., San Martin, J.   +7 more
core   +2 more sources

Mode of Action of Polygodial, an Antifungal Sesquiterpene Dialdehyde [PDF]

Agricultural and Biological Chemistry, 1988
The mechanism of polygodial antifungal action was studied using Saccharomyces cerevisiae. It inhibited the incorporation of radioactive precursors into macromolecules in whole cells. However, no specificity in the inhibition of precursor incorporation was observed among various species of macromolecules, i.e., DNA, RNA, protein, and polysaccharide.
Makoto TANIGUCHI, Yoshihisa YANO, Etsuo TADA, Kohji IKENISHI, Susumu OI, Hiroyuki HARAGUCHI, Kensuke HASHIMOTO, Isao KUBO   +7 more
openaire   +2 more sources

Anthelmintic Agents from African Medicinal Plants: Review and Prospects

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Soil‐transmitted helminthiasis affects more than 1.5 billion people globally and largely remains a sanitary problem in Africa. These infections place a huge economic burden on poor countries and affect livestock production, causing substantial economic losses and poor animal health. The emergence of anthelmintic resistance, especially in livestock, and
Jonathan Jato, Emmanuel Orman, Yaw Duah Boakye, Emelia Oppong Bekoe, Samuel Oppong Bekoe, Samuel Asare-Nkansah, Verena Spiegler, Andreas Hensel, Eva Liebau, Christian Agyare, Harish Chandra   +10 more
wiley   +1 more source

Chemical composition and anti-inflammatory evaluation of essential oils from leaves and stem barks from Drimys brasiliensis Miers (Winteraceae) [PDF]

, 2010
The essential oils from leaves and stem barks from Drimys brasiliensis Miers (Winteraceae) were individually obtained by hydrodistillation and their compounds characterized by use of GC/FID and GC/MS.
Carvalho, Larissa A. C, Fávero, Oriana A, Lago, Joao Henrique Ghilardi, Romoff, Paulete, Silva, Flávia S. da, Toyama, Daniela de O   +5 more
core   +2 more sources

Conventional Medicinal Uses, Phytoconstituents, and Biological Activities of Euphorbia officinarum L.: A Systematic Review

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2022, Issue 1, 2022., 2022
The Moroccan endemic plant Euphorbia officinarum is a traditional medicinal plant, known locally as “Daghmus.” Plants in the genus Euphorbia are well known for the chemical diversity of their diterpenoids and isoprenoid constituents, which perform many activities such as cytotoxic, antimicrobial, and anti‐inflammatory activities, as well as different ...
Imane Chamkhi, Mohamed Hnini, Jamal Aurag, Heng Yen Khong   +3 more
wiley   +1 more source

Chemical and Cytotoxic Activity of three main Sesquiterpenoids from Warburgia ugandensis

Results in Chemistry, 2021
Plant materials of Warburgia ugandensis have long been used in traditional African medicine due to their broad spectrum of biological activity. Here, we describe an efficient and mild isolation of three major compounds polygodial 1a, warburganal 2a, and ...
Reni Kitte, Maik Tretbar, Sarah Dluczek, Lorenz Beckmann, Peter Marquardt, Anna Duenkel, Andreas Schubert, Stephan Fricke, U. Sandy Tretbar   +8 more
doaj   +1 more source

Study on the Cytotoxic Activity of Drimane Sesquiterpenes and Nordrimane Compounds against Cancer Cell Lines

Molecules, 2014
Twelve drimanes, including polygodial (1), isopolygodial (2), drimenol (3), confertifolin (4), and isodrimenin (5), were obtained from natural sources.
Ivan Montenegro, Giacomo Tomasoni, Claudia Bosio, Natalia Quiñones, Alejandro Madrid, Hector Carrasco, Andres Olea, Rolando Martinez, Mauricio Cuellar, Joan Villena   +9 more
doaj   +1 more source

Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study [PDF]

, 2013
Peer reviewedPublisher ...
Gow, Neil A R, Lee, Keunsook, Munro, Carol A, Pietro, Rosemeire C L R, Preechasuth, Kanya, Santos, Emerson, Severi, Juliana A, Souza-Moreira, Tatiana M, Vilegas, Wagner   +8 more
core   +4 more sources

Effect of Polygodial on the Mitochondrial ATPase of Saccharomyces cerevisiae [PDF]

Antimicrobial Agents and Chemotherapy, 2000
ABSTRACT The fungicidal mechanism of a naturally occurring sesquiterpene dialdehyde, polygodial, was investigated in Saccharomyces cerevisiae . In an acidification assay, polygodial completely suppressed the glucose-induced decrease in external pH at 3.13 μg/ml, the same as the fungicidal concentration ...
C. Lunde, I. Kubo
semanticscholar   +3 more sources