Results 61 to 70 of about 379,094 (142)

Non-Destructive Monitoring via Electrochemical NADH Detection in Murine Cells

Biosensors, 2022
Nicotinamide adenine dinucleotide (NADH) is an important cofactor involved in metabolic redox reactions in living cells. The detection of NADH in living animal cells is a challenge.
Ju Kyung Lee, Han Na Suh, Sung Hoon Yoon, Kyu Hong Lee, Sae Young Ahn, Hyung Jin Kim, Sang Hee Kim   +6 more
doaj   +1 more source

p53: A Key Protein That Regulates Pulmonary Fibrosis

Oxidative Medicine and Cellular Longevity, Volume 2020, Issue 1, 2020., 2020
Pulmonary fibrosis is a progressively aggravating lethal disease that is a serious public health concern. Although the incidence of this disease is increasing, there is a lack of effective therapies. In recent years, the pathogenesis of pulmonary fibrosis has become a research hotspot.
Qi Wu, Ke-jia Zhang, Shi-min Jiang, Lu Fu, Yue Shi, Ru-bin Tan, Jie Cui, Yao Zhou, Emiliano Barreto   +8 more
wiley   +1 more source

Solid-phase extraction and fluorimetric determination of Zn (II) in natural water using novel adsorbent based on silica modified with polyhexamethylene guanidine and Ferron [PDF]

, 2021
Novel silica-based adsorbent layer-by-layer modified with polyhexamethylene guanidine and 7-iodine-8-hydroxyquinoline-5-sulphonic acid (Ferron) was used for preconcentration and adsorption-fluorimetric determination of Zn(II). A simple and express method
Didukh-Shadrina, S. L., Buyko, O. V., Losev, V. N.   +2 more
core   +1 more source

Time-course transcriptomic alterations reflect the pathophysiology of polyhexamethylene guanidine phosphate-induced lung injury in rats

, 2020
Objective: Humidifier-disinfectant-induced lung injury is a new syndrome associated with a high mortality rate and characterized by severe hypersensitivity pneumonitis, acute interstitial pneumonia, or acute respiratory distress syndrome ...
Dong Im Kim (8349381), Kyuhong Lee (4967659), Mi-Kyung Song (1763068)   +2 more
core   +1 more source

Comparative in vitro Antibacterial Activity of Polyhexamethylene Guanidine Hydrochloride and Polyhexamethylene Guanidine Succinate

Антибиотики и Химиотерапия, 2020
Eye infection is one of the temporary invalidity causes that can lead to blindness. The former antibacterial components of eye drops were polyhexamethylene guanidine hydrochloride and polyhexamethylene guanidine phosphate.
Kam An Cha, N. E. Grammatikova, I. A. Vasilenko, S. A. Kedik   +3 more
doaj  

Evaluation of polyhexamethylene guanidine-induced lung injuries by chest CT, pathologic examination, and RNA sequencing in a rat model

Scientific Reports, 2021
Our aim was to correlate chest CT and pathologic findings of polyhexamethylene guanidine phosphate (PHMG)-induced lung injuries in a rat model, to determine whether PHMG exposure causes lung tumors, and to explore genetic alterations according to PHMG ...
Cherry Kim, Sang Hoon Jeong, Jaeyoung Kim, Ki Yeol Lee, Jaehyung Cha, Chang Hyun Lee, Eun-Kee Park, Ju-Han Lee   +7 more
doaj   +1 more source

SARS-CoV-2 infection exacerbates fibrosis and develops new-onset asthma in damaged lung by polyhexamethylene guanidine phosphate.

Journal of Hazardous Materials
Modern society faces a variety of respiratory-related threats from the increased use of chemicals and periodic outbreaks of infectious diseases. This study investigates the connection between chemically-induced lung damage and SARS-CoV-2 infection ...
Seulgi Jeon, Young Kyu Kim, Gyun-baek Seo, Gi-Jun Oh, Sun-Taek Leem, Jeongah Song, Mi-Jin Yang, Jeong-yeon Hwang, Min-Seok Kim   +8 more
semanticscholar   +1 more source

Safety study, anti-inflammatory and antioxidant action of drug caramel with polyhexamethylene guanidine phosphate [PDF]

, 2017
Background: Among the new antiseptic medicines, most meeting modern requirements in terms of treatment of microbial invasion are one of the leading positions occupied by the polymeric guanidine compound.
Belenichev, Igor F., Hladyshev, Vitalii V., Kurinnyi, Anton V.   +2 more
core   +1 more source

Kathon Induces Fibrotic Inflammation in Lungs: The First Animal Study Revealing a Causal Relationship between Humidifier Disinfectant Exposure and Eosinophil and Th2-Mediated Fibrosis Induction

Molecules, 2020
Currently available toxicity data on humidifier disinfectants are primarily limited to polyhexamethylene guanidine phosphate-induced lung fibrosis.
Mi-Kyung Song, Dong Im Kim, Kyuhong Lee
doaj   +1 more source

Differential toxicity of polyhexamethylene guanidine phosphate administered through intravenous injection and intratracheal instillation in Sprague-Dawley rats.

Food and Chemical Toxicology
This study investigated the median lethal dose and target organs of polyhexamethylene guanidine phosphate (PHMG-P)-an antimicrobial disinfectant-administered via single-dose intravenous injection (IV; 3.13, 6.25, or 12.5 mg/kg) and intratracheal ...
Se-Woong Park, In-Sik Shin, Sung-Hwan Kim, Hanwook Suh   +3 more
semanticscholar   +1 more source