Results 91 to 100 of about 170 (119)
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Activity of the Antiseptic Polyhexanide Against Gram-Negative Bacteria
Microbial Drug Resistance, 2013The activity of the antiseptic polyhexanide was tested against 250 gram-negative clinical isolates, that is, 50 isolates each of Escherichia coli , Klebsiella pneumoniae , Pseudomonas aeruginosa ,
Werner Hugo Karl, Fabry +2 more
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Toxicity of Polyhexanide and Hydrogen Peroxide on Human Chondrocytes In Vitro
Orthopedics, 2011The treatment of acute joint infections has an important impact on long-term outcome and remains an unsolved problem. The most frequent bacteria are staphylococci, streptococci, and gram-negative bacteria. In septic surgery, polyhexanide and hydrogen peroxide are the most frequently used local antiseptics.
Eric, Röhner +5 more
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Advances in Skin & Wound Care, 2012
The study evaluated eradication of methicillin-resistant Staphylococcus aureus (MRSA) from pressure ulcers comparing swabs containing polyhexanide with a cellulose dressing + polyhexanide. After receiving approval from the ethics committee and informed consent, patients from the centers were recruited.Prospective randomized study.
Thomas, Wild +5 more
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The study evaluated eradication of methicillin-resistant Staphylococcus aureus (MRSA) from pressure ulcers comparing swabs containing polyhexanide with a cellulose dressing + polyhexanide. After receiving approval from the ethics committee and informed consent, patients from the centers were recruited.Prospective randomized study.
Thomas, Wild +5 more
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[The effectiveness of a 0.1% polyhexanide gel].
Revista de enfermeria (Barcelona, Spain), 2008In recent years, there has been an increase in the number of studies dealing with chronic wound infections which have led to the use of new terms such as critical colonization or bacterial films which, together with a patient's base conditions, are closely related to the cicatrisation process, especially regarding the stagnation or regression of this ...
Andrés Roldán, Valenzuela +1 more
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A Case of Severe Anaphylaxis to Polyhexanide: Cross-Reactivity between Biguanide Antiseptics
International Archives of Allergy and Immunology, 2017We present the case of a 77-year-old female patient who suffered from severe anaphylaxis during wound care. Allergologic evaluation yielded specific IgE antibodies to chlorhexidine, but anaphylaxis to chlorhexidine was not congruent with the patient history and dermal provocation tests. However, skin prick tests provided evidence for a sensitization to
Jo Ana Schunter +2 more
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Severe anaphylaxis to a new disinfectant: polyhexanide, a chlorhexidine polymer.
Schweizerische medizinische Wochenschrift, 1998We describe the cases of an 18-year-old female and a 15-year-old male who developed severe anaphylaxis following contact of surgical wounds with the disinfectant Lavasept, containing polyhexanide, a polymerised form of chlorhexidine, during orthopaedic interventions.
Olivieri, Juan Ignacio +2 more
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Clinical Safety and Efficacy of a Novel Thermoreversible Polyhexanide-Preserved Wound Covering Gel
European Surgical Research, 2010<i>Background:</i> An ideal topical formulation for wound therapy does not exist. The aim of this study was to develop a novel improved therapeutic option for the treatment of acute and chronic wounds. <i>Methods:</i> A transparent wound gel which is in a liquid state below and in a gel state at or above room temperature was ...
O, Goertz +7 more
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Journal of Wound Care, 2011
Objective: This cohort study evaluated the clinical efficacy of a polyhexanide-containing biocellulose dressing, Suprasorb X + PHmb (lohmann & Rauscher GmbH), for the eradication of biofilms in non-healing wounds. Polyhexanide (PHmb) has been shown to have microbicidal activity when applied to chronic wounds and burns. Method: Twenty-eight patients,
E, Lenselink, A, Andriessen
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Objective: This cohort study evaluated the clinical efficacy of a polyhexanide-containing biocellulose dressing, Suprasorb X + PHmb (lohmann & Rauscher GmbH), for the eradication of biofilms in non-healing wounds. Polyhexanide (PHmb) has been shown to have microbicidal activity when applied to chronic wounds and burns. Method: Twenty-eight patients,
E, Lenselink, A, Andriessen
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[Lethal intravenous infusion of a wound antiseptic containing polyhexanide].
Archiv fur Kriminologie, 2009Polyhexamethylene biguanide (PHMB) is considered to be highly histocompatible and is one of the most frequently used wound antiseptics. Only one case of intoxication has been reported so far. The present case of a lethal intoxication is the first fatal incident described where causality is substantiated by a temporal coincidence between application and
Frank, Wehner +2 more
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[Suspected anaphylaxis by wound treatment with polyhexanide derivate wound products].
Ugeskrift for laeger, 2018Only four cases of anaphylaxis triggered by polyhexanide have been reported in the literature. We report a case of anaphylaxis in a Danish patient treated with polyhexanide derivate (Prontosan) wound products. We emphasise the importance of intramuscular injection of adrenaline as part of the treatment protocol in the initial phase of anaphylaxis and ...
Morten A, Schrøder +2 more
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