Results 111 to 120 of about 729 (148)

Lipopeptide antibiotics disrupt interactions of undecaprenyl phosphate with UptA. [PDF]

Proc Natl Acad Sci U S A
Oluwole AO, Kalmankar NV, Guida M, Bennett JL, Poce G, Bolla JR, Robinson CV.   +6 more
europepmc   +1 more source

Tolerance mechanisms in polysaccharide biosynthesis: Implications for undecaprenol phosphate recycling in Escherichia coli and Shigella flexneri. [PDF]

PLoS Genet
Qin J, Hong Y, Maczuga NT, Morona R, Totsika M.   +4 more
europepmc   +1 more source

The role of protein prenylation inhibition through targeting FPPS by zoledronic acid in the prevention of renal fibrosis in rats. [PDF]

Sci Rep
Mohamed RH, Abdelrahim DS, Hay NHA, Fawzy NM, M DKM, Yehia DAY, AbdelMaksoud OM, Tamim YM.   +7 more
europepmc   +1 more source

Chemoenzymatic Formation of Oxa-Terpenoids by Sesqui- and Diterpene Synthase-Mediated Biotransformations with 9-Oxy-FPP Ether Derivatives. [PDF]

Biochemistry
Struwe H, Nguyen T, Schwörer S, Droste J, Spinck H, Kirschning A.   +5 more
europepmc   +1 more source

Functional and biosynthetic investigation of polyisoprenoids in roses leaves. [PDF]

Planta
Weremczuk A, Steczkiewicz K, Boachon B, Skorupińska-Tudek K, Jozwiak A, Surmacz L.   +5 more
europepmc   +1 more source

Polyisoprenyl phosphates in intracellular signalling

Nature, 1997
In response to environmental stimuli, leukocyte membrane remodelling generates biologically active lipids that can serve as both intra- and extracellular mediators. There are several classes of lipids that can mediate inflammatory reactions. We report here on a new intracellular lipid signal that regulates oxygen-radical formation in neutrophils, a key
Bruce D. Levy, Nicos A. Petasis, Charles N. Serhan   +2 more
openalex   +3 more sources

A Novel Polyisoprenyl Phosphate Signaling Cascade in Human Neutrophils

Annals of the New York Academy of Sciences, 2000
Abstract:Activation of neutrophil (PMN) surface receptors can evoke inflammation and tissue injury via aberrant release of excess effectors. The molecular mechanisms involved in host protection and control of PMN responses have yet to be defined. As Billah and coworkers (1989) and Exton (1997), for example, have pointed out, phospholipase D (PLD ...
Bruce D. Levy, Charles N. Serhan
openalex   +3 more sources

Characterization of polyisoprenyl phosphate phosphatase activity in rat liver

Archives of Biochemistry and Biophysics, 1986
The polyisoprenyl phosphate dephosphorylating activity of rat liver has been investigated with regard to substrate specificity, subcellular distribution, and transmembrane orientation. Total liver microsomes were employed as a source of enzymatic activity against a variety of 32P-labeled substrates.
R. Kennedy Keller, W. Lee Adair, Nancy Cafmeyer, Francesca Simion, Becca Fleischer, Sidney Fleischer   +5 more
openalex   +3 more sources

Polyisoprenyl Phosphate Signaling: Topography in Human Neutrophils

Biochemical and Biophysical Research Communications, 2000
To determine the relationship of polyisoprenyl phosphate (PIPP) remodeling and signaling to the activation state of human neutrophils (PMN), we examined the impact of leukotriene B(4) (LTB(4)) on the conversion of a unique bioactive isoprenoid (presqualene diphosphate: PSDP), recently identified as a novel endogenous signaling molecule.
Bruce D. Levy, Charles N. Serhan
openalex   +3 more sources

Characterization of Mannolipids Formed in a Calf Pancreatic Microsomal Fraction from Guanosine Diphosphate [14C]Mannose and either Endogenous Lipid or Exogenous Polyisoprenyl Phosphates

Biochemical Society Transactions, 1973
In some glycoproteins, a glycosylamine bond between 2-acetamido-2-deoxy-~-glucose and the amide group of asparagine serves to link oligosaccharide with peptide. A common oligosaccharide unit containing 2-acetamido-2-deoxy-~-glucose and D-mannose residues has been suggested for the linkage region of these glycoproteins (Lee & Scocca, 1972).
Jan S. Tkacz, Annetté Herscovics, Christopher D. Warren, Roger W. Jeanloz   +3 more
openalex   +2 more sources