Results 31 to 40 of about 712 (131)
The Scientific World Journal, Volume 7, Issue 1, Page 1393-1412, 2007., 2007 Lipoxins (LXs) represent a class of arachidonic acid (AA) metabolites that carry potent immunoregulatory and anti‐inflammatory properties, LXA4 and LXB4 being the main components of this series. LXs are generated by cooperation between 5‐lipoxygenase (LO) and 12‐ or 15‐LO during cell‐cell interactions or by single cell types.
Mario Romano +3 more
wiley +1 more source
A genome-wide MeSH-based literature mining system predicts implicit gene-to-gene relationships and networks [PDF]
, 2015 Background The large amount of literature in the post-genomics era enables the study of gene interactions and networks using all available articles published for a specific organism.
He, Yongqun +3 more
core +1 more source
The Scientific World Journal, Volume 2, Issue 1, Page 169-204, 2002., 2002 It is well appreciated that lipid‐derived mediators play key roles in inflammation and many other physiologic responses where multicellular processes are involved. Among them, lipoxins (LX) and aspirin‐triggered LX (ATL) evoke actions of interest in a range of physiologic and pathophysiologic processes, and these two series have emerged as founding ...
Charles N. Serhan, Nan Chiang
wiley +1 more source
Structural elucidation of the cis -prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation [PDF]
, 2020 Cis- prenyltransferase ( cis- PTase) catalyzes the rate-limiting step in the synthesis of glycosyl carrier lipids required for protein glycosylation in the lumen of endoplasmic reticulum.
Edani, Ban H +7 more
core +1 more source
Small molecule inhibitors of mammalian glycosylation [PDF]
, 2022 Glycans are one of the fundamental biopolymers encountered in living systems. Compared to polynucleotide and polypeptide biosynthesis, polysaccharide biosynthesis is a uniquely combinatorial process to which interdependent enzymes with seemingly broad ...
Almahayni, K. +5 more
core +2 more sources
Controlling Glycosyltransferase Activity: Inhibition and Enzyme Engineering [PDF]
, 2021 Glycosyltransferases (GTs) are responsible for the synthesis of a multitude of important glycosylated molecules. These enzymes catalyze the assembly of glycans and glycoconjugates through the transfer of sugar residues from activated donors onto various ...
Ghosh, Trisha +3 more
core +1 more source
The cis‐prenyltransferase protein family in Taraxacum koksaghyz
The Plant Journal, Volume 121, Issue 3, February 2025.Significance Statement The novelty of this work lies in the comprehensive description of cis‐prenyl transferases in the rubber‐producing plant Taraxacum koksaghyz. This provides valuable insights for breeding and rational protein design in heterologous systems.
Boje Müller +6 more
wiley +1 more source
Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design [PDF]
, 2018 Summary: Protein N-glycosylation is a widespread post-translational modification. The first committed step in this process is catalysed by dolichyl-phosphate N-acetylglucosamine-phosphotransferase DPAGT1 (GPT/E.C. 2.7.8.15).
Barry III, Clifton E. +31 more
core +5 more sources
Investigating asparagine-linked glycosylation substrate : specificity and effects on protein folding [PDF]
, 2009 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009.Vita.Includes bibliographical references.N-linked glycosylation is a ubiquitous form of protein modification whereby a preassembled oligosaccharide is covalently attached ...
Chen, Mark M
core
Physiological Impact of Abnormal Lipoxin A 4 [PDF]
, 2015 Lipoxin A4 has been described as a major signal for the resolution of inflammation and is abnormally produced in the lungs of patients with cystic fibrosis (CF).
Fiona Ringholz +4 more
core +5 more sources