Results 21 to 30 of about 712 (131)
Topological analysis of the Escherichia coli WcaJ protein reveals a new conserved configuration for the polyisoprenyl-phosphate hexose-1-phosphate transferase family [PDF]
Scientific Reports, 2015 AbstractWcaJ is an Escherichia coli membrane enzyme catalysing the biosynthesis of undecaprenyl-diphosphate-glucose, the first step in the assembly of colanic acid exopolysaccharide. WcaJ belongs to a large family of polyisoprenyl-phosphate hexose-1-phosphate transferases (PHPTs) sharing a similar predicted topology consisting of an N-terminal domain ...
Furlong, Sarah E. +3 more
openaire +4 more sources
Francisella tularensis Schu S4 lipopolysaccharide core sugar and o-antigen mutants are attenuated in a mouse model of tularemia [PDF]
, 2014 The virulence factors mediating Francisella pathogenesis are being investigated, with an emphasis on understanding how the organism evades innate immunity mechanisms.
Apicella, Michael A +6 more
core +2 more sources
Nucleotide Sugars in Chemistry and Biology [PDF]
, 2022 Nucleotide sugars have essential roles in every living creature. They are the building blocks of the biosynthesis of carbohydrates and their conjugates.
Satu Mikkola
core +1 more source
Journal of Biological Chemistry, 1985 The enzymatic dephosphorylation of endogenous and exogenous dolichyl phosphate (Dol-P) by membrane preparations from calf brain has been reported previously (Burton, W.A., Scher, M.G., and Waechter, C. J. (1981) Arch. Biochem. Biophys. 208, 409-417). The study presented here shows that polyisoprenyl phosphate phosphatase activity increases with age in ...
M G, Scher, C M, Sumbilla, C J, Waechter
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Lipid Mediators in Inflammation [PDF]
, 2016 Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core +1 more source
Dolichyl-phosphomannose synthase from the Archae Thermoplasma acidophilum [PDF]
, 1996 Archae (formerly Archaebacteria) comprise an entire kingdom of organisms placed halfway between prokaryotes and eucaryotes in evolution, This class of organisms lacks murein cell wall and is devoid of organelles, yet Archae synthesize and export N-linked
Laine, Roger A., Zhu, Betty C.R.
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Molecular Microbiology, Volume 112, Issue 4, Page 1178-1198, October 2019., 2019 Myxococcus xanthus displays several social behaviors involving cell–cell contacts. To understand the role of the lipopolysaccharide (LPS) in these behaviors, we identified key enzymes involved in O‐antigen and LPS biosynthesis: the polyisoprenyl‐phosphate hexose‐1‐phosphate transferase, responsible for priming O‐antigen synthesis and the O‐antigen ...
María Pérez‐Burgos +4 more
wiley +1 more source
Poly-saturated dolichols from filamentous fungi modulate activity of dolichol-dependent glycosyltransferase and physical properties of membranes [PDF]
, 2019 Mono-saturated polyprenols (dolichols) have been found in almost all Eukaryotic cells, however, dolichols containing additional saturated bonds at the ω-end, have been identified in A. fumigatus and A. niger.
Bernat, Przemysław +14 more
core +2 more sources
The Molecular Mechanism of \u3cem\u3eN\u3c/em\u3e-Acetylglucosamine Side-Chain Attachment to the Lancefield Group A Carbohydrate in \u3cem\u3eStreptococcus pyogenes\u3c/em\u3e [PDF]
, 2017 In many Lactobacillales species (i.e. lactic acid bacteria), peptidoglycan is decorated by polyrhamnose polysaccharides that are critical for cell envelope integrity and cell shape and also represent key antigenic determinants.
Chen, Jing +8 more
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Molecular Circuits of Resolution in Airway Inflammation
The Scientific World Journal, Volume 10, Issue 1, Page 1386-1399, 2010., 2010 Inflammatory diseases of the lung are common, cause significant morbidity, and can be refractory to therapy. Airway responses to injury, noxious stimuli, or microbes lead to leukocyte recruitment for host defense. As leukocytes respond, they interact with lung resident cells and can elaborate specific mediators that are enzymatically generated from ...
Troy Carlo, Bruce D. Levy, Joan Clària
wiley +1 more source