Results 91 to 100 of about 15,660 (211)

Phylogenomic analysis of natural products biosynthetic gene clusters allows discovery of arseno-organic metabolites in model streptomycetes [PDF]

open access: yes, 2016
We are indebted with Marnix Medema, Paul Straight and Sean Rovito, for useful discussions and critical reading of the manuscript, as well as with Alicia Chagolla and Yolanda Rodriguez of the MS Service of Unidad Irapuato, Cinvestav, and Araceli Fernandez
Barona-Gomez, Francisco   +7 more
core   +1 more source

Deciphering the biosynthetic pathways of lichen acids

open access: yesNew Phytologist, EarlyView.
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim   +11 more
wiley   +1 more source

Production of Secondary Metabolites in Extreme Environments: Food- and Airborne Wallemia spp. Produce Toxic Metabolites at Hypersaline Conditions [PDF]

open access: yes, 2016
The food- and airborne fungal genus Wallemia comprises seven xerophilic and halophilic species: W. sebi, W. mellicola, W. canadensis, W. tropicalis, W. muriae, W. hederae and W. ichthyophaga.
Džeroski, Sašo   +5 more
core   +2 more sources

Equipped for success: genomes and metabolomes of the European Amanita muscaria are conserved in its novel South African range

open access: yesNew Phytologist, EarlyView.
Summary Plants and soils have been moved around the world for centuries, but invasive mushrooms receive scant attention. The Amanita muscaria species complex was introduced to South Africa in the context of forestry, but its origins, ecology and recent evolution are unstudied. We sequenced the genomes of 24 Northern and Southern Hemisphere A. muscaria,
Grant R. Nickles   +39 more
wiley   +1 more source

Novel Type III Polyketide Synthases Biosynthesize Methylated Polyketides in Mycobacterium marinum [PDF]

open access: yesScientific Reports, 2018
AbstractMycobacterial pathogenesis is hallmarked by lipidic polyketides that decorate the cell envelope and mediate infection. However, factors mediating persistence remain largely unknown. Dynamic cell wall remodeling could facilitate the different pathogenic phases.
Amreesh Parvez   +5 more
openaire   +3 more sources

TaRIP2 Positively Regulates Wheat Pollen Wall Formation Through MYB80‐Controlled Lipid Metabolism

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Male‐sterile genes and mutants are critical for hybrid seed production in monocotyledonous crops. Lipids are essential structural components of male reproductive organs, such as the anther and pollen. Here, we show that the pollen‐preferential gene TaRIP2 is essential for wheat anther development and pollen formation. RT‐qPCR analysis revealed
Ran Han   +14 more
wiley   +1 more source

A novel class of plant type III polyketide synthase involved in orsellinic acid biosynthesis from Rhododendron dauricum

open access: yesFrontiers in Plant Science, 2016
Rhododendron dauricum L. produces daurichromenic acid, the anti-HIV meroterpenoid consisting of sesquiterpene and orsellinic acid moieties. To characterize the enzyme responsible for orsellinic acid biosynthesis, a cDNA encoding a novel polyketide ...
Futoshi Taura   +9 more
doaj   +1 more source

OsMT2b Regulates Pollen Development and ROS Homeostasis in a Photoperiod‐Dependent Manner

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Reactive oxygen species (ROS) are signalling molecules that promote programmed cell death in animal and plant systems. However, their role in rice (Oryza sativa L.) anther development is unclear. In this study, we show that lower transcript levels of the metallothionein gene OsMT2b in japonica rice plants obtained by RNA interference (RNAi ...
Ying He   +9 more
wiley   +1 more source

Reprogramming of the Aurantinin Polyketide Assembly Line to Synthesize Auritriacids by Excising an Atypical Enoyl‐CoA Hydratase Domain

open access: yesAdvanced Science
Modular polyketide synthases (PKSs) are capable of synthesizing diverse natural products with fascinating bioactivities. Canonical enoyl‐CoA hydratases (ECHs) are components of the β‐branching cassette that modifies the polyketide chain by adding a β ...
Dacheng Wang   +5 more
doaj   +1 more source

Exploiting the Biosynthetic Potential of Type III Polyketide Synthases

open access: yesMolecules, 2016
Polyketides are structurally and functionally diverse secondary metabolites that are biosynthesized by polyketide synthases (PKSs) using acyl-CoA precursors.
Yan Ping Lim   +2 more
doaj   +1 more source

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