Results 91 to 100 of about 8,226 (181)

Animal FAS-like polyketide synthases produce diverse polypropionates. [PDF]

Proc Natl Acad Sci U S A, 2023
Li F, Lin Z, Krug PJ, Catrow JL, Cox JE, Schmidt EW.   +5 more
europepmc   +1 more source

Traffic Control in Modular Polyketide Synthases

ACS Central Science, 2016
Kara Finzel, Michael D. Burkart
doaj   +1 more source

A CRISPR-Cas9 system for knock-out and knock-in of high molecular weight DNA enables module-swapping of the pikromycin synthase in its native host

Microbial Cell Factories
Background Engineers seeking to generate natural product analogs through altering modular polyketide synthases (PKSs) face significant challenges when genomically editing large stretches of DNA.
Zhe-Chong Wang, Hayden Stegall, Takeshi Miyazawa, Adrian T. Keatinge-Clay   +3 more
doaj   +1 more source

Polyketide synthases mutation in tuberculosis transmission revealed by whole genomic sequence, China, 2011-2019. [PDF]

Front Genet, 2023
Wang TT, Hu YL, Li YF, Kong XL, Li YM, Sun PY, Wang DX, Li YY, Zhang YZ, Han QL, Zhu XH, An QQ, Liu LL, Liu Y, Li HC.   +14 more
europepmc   +1 more source

Biosensor Guided Polyketide Synthases Engineering for Optimization of Domain Exchange Boundaries. [PDF]

Nat Commun, 2023
Englund E, Schmidt M, Nava AA, Klass S, Keiser L, Dan Q, Katz L, Yuzawa S, Keasling JD.   +8 more
europepmc   +1 more source

Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies. [PDF]

ACS Synth Biol, 2023
Schmidt M, Lee N, Zhan C, Roberts JB, Nava AA, Keiser LS, Vilchez AA, Chen Y, Petzold CJ, Haushalter RW, Blank LM, Keasling JD.   +11 more
europepmc   +1 more source

Diene incorporation by a dehydratase domain variant in modular polyketide synthases. [PDF]

Nat Chem Biol, 2022
Hobson C, Jenner M, Jian X, Griffiths D, Roberts DM, Rey-Carrizo M, Challis GL.   +6 more
europepmc   +1 more source

Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata. [PDF]

Microbiologyopen, 2023
Ahmad N, Ritz M, Calchera A, Otte J, Schmitt I, Brueck T, Mehlmer N.   +6 more
europepmc   +1 more source

In silicio expression analysis of PKS genes isolated from Cannabis sativa L.

Genetics and Molecular Biology, 2010
Cannabinoids, flavonoids, and stilbenoids have been identified in the annual dioecious plant Cannabis sativa L. Of these, the cannabinoids are the best known group of this plant's natural products.
Isvett J. Flores-Sanchez, Huub J.M. Linthorst, Robert Verpoorte   +2 more
doaj  

Corrigendum: Engineered biosynthesis of plant polyketides by type III polyketide synthases in microorganisms. [PDF]

Front Bioeng Biotechnol, 2022
Liu C, Li S.
europepmc   +1 more source