Results 141 to 150 of about 20,629 (261)

Two γ‐Lactone Derivatives With Anti‐Inflammatory Activities From a Mangrove Endophytic Fungus Alternaria sp. HN‐17

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Two new γ‐lactone derivatives, alterlactones A–B (1–2), and a known analogue, 3were isolated from Alternaria sp. HN‐17. Their structures were elucidated by NMR, HRESIMS and ECD calculations. Both 1 and 2 showed potent anti‐inflammatory activity. ABSTRACT Two γ‐lactone derivatives, alterlactones A‐B (1–2), along with one known analogue 3, were isolated ...
Yuru Sun, Bingbing Qian, Ruxue Mu, Zhongqian Xue, Linxuan Wu, Xin Huang, Yan Chen   +6 more
wiley   +1 more source

Chemical Constituents of the Deep‐Sea‐Derived Fungus Talaromyces wortmannii and Their Ferroptosis Inhibitory Activity

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
One new tyramine derivative (1) and 28 known compounds (2–29) were isolated from deep‐sea‐derived fungus Talaromyces wortmannii. Their structures were elucidated by NMR/MS and computational calculations. Compounds 2 and 6 potently inhibited ferroptosis with EC5₀ values of 4.52 and 13.73 µM.
Ke‐Xin Ma, Zheng‐Biao Zou, Qi‐Qian Wu, Li‐Sheng Li, Ying‐Ni Pan, Xian‐Wen Yang   +5 more
wiley   +1 more source

Flavasperfurans A and B, Two New Asperfuran Derivatives From the Marine‐Derived Fungus Aspergillus flavus

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Two new asperfurans (1 and 2) and 23 known compounds from marine Aspergillus flavus were characterized by NMR, HRESIMS, DP4+, and ECD. Asperfuran (3) potently inhibited RSL3‐induced ferroptosis (EC50 = 0.81 µM). ABSTRACT Marine microorganisms represent a prolific reservoir of chemically diverse natural products endowed with considerable therapeutic ...
Chun‐Xiu Wang, Zheng‐Biao Zou, Li‐Sheng Li, Cheng‐Hai Gao, Xian‐Wen Yang   +4 more
wiley   +1 more source

Insights Into Aggregation‐Delayed Phenotype of Dictyostelium discoideum

Cell Biology International, Volume 50, Issue 9, September 2026.
ABSTRACT Dictyostelium discoideum is a cellular model that has been widely used in cell signal research focusing on different cellular and developmental processes. The unique lifecycle of these cells—which involves switching between vegetative and development phases—makes Dictyostelium a reliable model for investigations in this field.
Sarah Abdulaziz Alamer
wiley   +1 more source

Tandyukisins K-P, New Decalin Polyketides from <i>Trichoderma longicollum</i> 17007 with Antitubercular Activity Against <i>Mycobacterium tuberculosis</i> H37Ra. [PDF]

Antibiotics (Basel)
Yu J, Ning S, Di Y, Feng H, Li X, Wang K, Wang R, Ma M, Pan S, Jiang C, Jiang Y, Hsiang T, Chen J, Zhang W, Zhang L, Liu X, Zhang X, Zhu G.   +17 more
europepmc   +1 more source

Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α‐Mangostin: A Structure–Activity Relationship Insight

ChemFoodChem, Volume 2, Issue 3, September 2026.
Free phenolic hydroxyl groups in the chemical structure of the natural xanthone α‐mangostin (MGT) contribute positively to achieving the anticancer profile against murine colon cancer, murine triple negative breast cancer, and human osteosarcoma cancer. ABSTRACT The α‐mangostin (MGT) is a natural xanthone obtained from the pericarp of mangosteen fruit (
Otávio Augusto Chaves, Afonso Santine M. M. Velez, Lívia Stenico, Douglas Chaves de Alcântara Pinto, Debora Decote‐Ricardo, Eliezer Avila Gandra, Marco Edilson Freire de Lima, Carlos Serpa   +7 more
wiley   +1 more source

Orsellinic Acid from the Endophytic <i>Fusarium oxysporum</i> Drives Specialized Metabolism in <i>Peperomia obtusifolia</i>. [PDF]

ACS Omega
de Lima WG, Morandim-Giannetti AA, Bronzel Júnior JL, López SN, Kato MJ, Furlan M.   +5 more
europepmc   +1 more source

Gut Microbiota Differences in Wild Asian Elephants From Pu'er, China

Ecology and Evolution, Volume 16, Issue 9, September 2026.
This study compared the gut microbiota of two wild Asian elephant populations in Jiangcheng (JC) and Liushun (LS), Yunnan, China. Significant differences in microbial structure, diversity, and function were found. Across samples, 24 phyla, 48 classes, 98 orders, 164 families, 288 genera, and 351 species were annotated.
Zheng Jing, Zhou Jiuxuan, Liu Xia, Wang Binghui, Wang Yixuan, Cao Hui, Lu Tihuo   +6 more
wiley   +1 more source

Pangenome of Streptomyces sampsonii and Relatives Highlights Horizontal Gene Transfer and Secondary Metabolism in Environmental Adaptation and Ecological Significance

Ecology and Evolution, Volume 16, Issue 9, September 2026.
This study presents a chromosome‐level genome assembly of Streptomyces sampsonii and a pangenome analysis of 95 strains, revealing a highly expansive “open” pangenome. Our results highlight that horizontal gene transfer (HGT) and accessory gene variations drive the evolution of secondary metabolism and environmental adaptation.
Boyang Zhang, Shuo Ji
wiley   +1 more source

Resorcylic Acid Lactones and Isocoumarin Derivatives from the Marine-Associated Polar Fungus <i>Penicillium</i> sp. OUCMDZ-4014. [PDF]

Mar Drugs
Yu D, Du R, Yu X, An C, Ding C, Wang J, Zhu W, Wang Y.   +7 more
europepmc   +1 more source