Antibacterial Polyketides from the Jellyfish-Derived Fungus Paecilomyces variotii
Four new polyketides (1-4) were isolated from the fungus Paecilomyces variotii, which was derived from the jellyfish Nemopilema nomurai. The planar structures and relative configurations of these polyketides were elucidated on the basis of spectroscopic ...
J Liu +16 more
core +1 more source
DISSECTING COMPLEX POLYKETIDE BIOSYNTHESIS
Numerous bioactive natural products are synthesised by modular polyketide synthases. These compounds can be made in high yield by native multienzyme assembly lines. However, formation of analogues by genetically engineered systems is often considerably less efficient.
openaire +4 more sources
Rapid Screening of Polyol Polyketides from Marine Dinoflagellates
Dinoflagellate-derived polyketides are typically large molecules (>1000 Da) with complex structures, potent bioactivities, and high toxicities. Their discovery suffers three major bottlenecks: insufficient bioavailability, low-yield cultivation of ...
María García-Altares (8946530) +4 more
core +1 more source
Chemical structures of the 22- to 26-membered macrocyclic polyketides discussed in this work.
Chemical structures of the 22- to 26-membered macrocyclic polyketides discussed in this work.
Markiyan Samborskyy (2572471) +2 more
core +1 more source
The structure diversity of type II polyketide synthases-derived bacterial aromatic polyketides is often enhanced by enzyme controlled or spontaneous cyclizations.
Yiguang Zhu (340294) +17 more
core +1 more source
Targeted Discovery of β‑Branched Conjugated Polyketides from Bacteria Based on Genomic and Metabolomic Hallmarks. [PDF]
Cui J +19 more
europepmc +1 more source
BisCEET: A Visual Browser for Biosynthetic Gene Clusters Aiding in the Identification of Natural Product Variants and Distinct Tailoring Enzymes. [PDF]
Sowa ST, Weddeling HG, Teufel R.
europepmc +1 more source
Novel bioactive compounds from marine-derived endosymbiotic Penicillium fungi reported during 2020-2025. [PDF]
Omran SA +3 more
europepmc +1 more source
Finding new molecules to prevent the growth of antimicrobial resistance is a hot topic for scientists worldwide. It has been reported that some raw bioproducts containing Monascus polyketides have antimicrobial activities, but extensive studies on this ...
Narcisa Băbeanu +6 more
core +1 more source
Untargeted Metabolomics for Profiling of Cascara, Senna, Rhubarb, and Frangula Metabolites. [PDF]
Nezi P +7 more
europepmc +1 more source

