Results 131 to 140 of about 20,629 (261)

Biosynthesis of polyketides by two type III polyketide synthases from Aloe barbadensis

, 2019
Various bioactive polyketides have been found in Aloe barbadensis. However, the polyketide synthases (PKSs), which participate in biosynthesis of polyketides in A. barbadensis remain unknown.
Ji-Mei Liu (812942), Ri-Dao Chen (778867), Da-Wei Chen (3032376), Lin Yang (45852), Ke-Bo Xie (3343502), Jun-Gui Dai (747425), Ai-Jing Liu (8070479), Song-Yang Sui (8070482), Yu-Yu Liu (1433647)   +8 more
core   +1 more source

DISSECTING COMPLEX POLYKETIDE BIOSYNTHESIS

Computational and Structural Biotechnology Journal, 2012
Numerous bioactive natural products are synthesised by modular polyketide synthases. These compounds can be made in high yield by native multienzyme assembly lines. However, formation of analogues by genetically engineered systems is often considerably less efficient.
openaire   +4 more sources

Testing the Keystone-Molecule Hypothesis: Do Defensive Polyketides from a Common Gastropod Alter Estuarine Communities?

, 2023
By analogy to keystone species, new theory proposes that compounds with disproportionate effects on ecosystems may be keystone molecules, regulating communities with outsized impacts relative to their abundance in the environment.
Nguyen, Helen
core  

Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco, M. Rusconi, J. Saglietto, P. Renzi, A. Deagostino, E. Azzi   +5 more
wiley   +1 more source

Enzyme@Silicone: A Versatile Combo for Robust Synthetic Biocatalysis?

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
Silicone‐based polymers are versatile materials for enzyme immobilization, offering unique advantages such as chemical inertness, thermal stability, and tunable morphology. This review highlights their applications in synthetic biocatalysis, from batch to continuous processes, and addresses key challenges such as mass transport limitations and ...
Marion B. Ansorge‐Schumacher
wiley   +1 more source

Metagenomic Association Uncovers Host Genotype‐Structured Rhizobacterial Networks and Novel Taxa That Enhance Soybean Salt Tolerance

Advanced Science, Volume 13, Issue 53, 24 September 2026.
An STI‐guided metagenomic association framework links soybean salt‐tolerance phenotypes with rhizosphere microbiome composition and network organization in natural saline soils. The approach identifies candidate beneficial taxa, including Thalassospira xiamenensis, and provides an efficient strategy for mining stress‐protective microbes from native ...
Yu Luo, Feng‐Li Kang, Qi‐Min Li, Wei‐Cai Yang   +3 more
wiley   +1 more source

Rapid Screening of Polyol Polyketides from Marine Dinoflagellates

Dinoflagellate-derived polyketides are typically large molecules (>1000 Da) with complex structures, potent bioactivities, and high toxicities. Their discovery suffers three major bottlenecks: insufficient bioavailability, low-yield cultivation of ...
María García-Altares (8946530), María L. Souto (1562152), Christian Hertweck (189607), José J. Fernández (1562155), Adrián Morales-Amador (13899053)   +4 more
core   +1 more source

Elucidating the Molecular Mechanisms of Vitex negundo L. in Polycystic Ovary Syndrome via Metabolomics‐Driven Network Pharmacology

Biomedical Chromatography, Volume 40, Issue 9, September 2026.
ABSTRACT Polycystic ovary syndrome (PCOS) is a hormonal disorder marked by irregular menstrual cycles, elevated androgen levels, ovarian cysts, hirsutism, acne and other symptoms. While conventional medications such as Metformin and Spironolactone are commonly prescribed, they are often associated with undesirable side effects.
Nishmitha R. Poojary, Neeharika Narisepalli Venkatasai, Kannath U. Sanjay, Supraja M. Kodanch, Padmalatha S. Rai   +4 more
wiley   +1 more source

Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris

Biological Diversity, Volume 3, Issue 3, Page 125-135, September 2026.
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu, Jia Li, Xin Liu, Xue‐Jun Ge, Hui‐Run Huang   +4 more
wiley   +1 more source

Phytochemical Profiling and Evaluation of Antibacterial, Anticancer, Anti‐inflammatory, and Wound‐Healing Activities of Endophytic Fungi Isolated From Atalantia racemosa

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
ABSTRACT Endophytic fungi are recognized as prolific sources of structurally diverse secondary metabolites with significant pharmaceutical potential. In the present study, endophytic fungi were isolated from healthy tissues of Atalantia racemosa (Rutaceae), an ethnomedicinal plant traditionally used for respiratory disorders and blood purification.
Sushma M, Arun Shettar, Joy Hoskeri, Vedamurthy A B   +3 more
wiley   +1 more source