Results 111 to 120 of about 20,629 (261)

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

open access: yesThe FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner   +8 more
wiley   +1 more source

Overlooked components of lipid metabolism: Odd‐chain polyunsaturated fatty acids in photosynthetic microorganisms

open access: yesJournal of Phycology, EarlyView.
Abstract This mini‐review examines odd‐carbon polyunsaturated fatty acids (odd‐PUFAs), a rare but biologically significant group of fatty acids in photosynthetic microorganisms. Odd‐PUFAs are straight‐chain fatty acids containing an odd number of carbon atoms and two or more methylene‐interrupted double bonds. They typically account for less than 1% of
Linda Nedbalová   +2 more
wiley   +1 more source

Cracking the Polyketide Code

open access: yesPLoS Biology, 2004
Polyketides, natural products from microorganisms, have been a main source of antibiotics. Understanding the 'programming' of the enzymes that produce these complex molecules has opened a new field of drug ...
openaire   +4 more sources

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor   +4 more
wiley   +1 more source

Synthesis of Six Natural Products Enabled by Selective Hydroxylation of Orcinaldehyde‐Like Substrates With an Enzyme Library

open access: yesAngewandte Chemie, Volume 138, Issue 38, 14 September 2026.
Achieving selective (sp3)C–H hydroxylation can streamline the synthesis of complex organic molecules. Biocatalysis presents an opportunity to realize this transformation, however, identifying useful enzymes that enable synthetic strategies can be a challenge due to limitations in enzyme substrate scope.
Gonzalo J. Villegas Rodríguez   +5 more
wiley   +2 more sources

Synthetic Studies Toward the Total Synthesis of Maklamicin and Related Spirotetronate Polyketides [PDF]

open access: yes, 2016
Spirotetronate polyketides are naturally occurring natural products that are highlighted by their complex structures and intruiging biological activities.
Lacoske, Michelle
core   +1 more source

Synthesis of Polyketides via Diastereoselective Acetalization

open access: yes, 2016
Diastereoselective acetalization of pseudo-C2-symmetric 1,3,5-triol systems is a general strategy for the rapid generation of polyketides. The oxidative acetalization reaction shown above was studied under both kinetic and thermodynamic conditions, using
David C. Myles (2338201)   +1 more
core   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee   +5 more
wiley   +1 more source

Genomics driven discovery and engineering of fungal polycyclic polyketides [PDF]

open access: yes, 2018
Polycyclic aromatic polyketides represent an important group of Natural Products (NPs) exhibiting a broad variety of antimicrobial and cytotoxic ...
Subko, Karolina   +7 more
core  

Ecological Filtering by Tuber Compartments Shapes Stable Core Microbiomes That Underpin Potato Plant Growth Across Environments

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Harnessing plant microbiomes for sustainable agriculture requires understanding not only whether they can boost crop performance, but also how ecological processes govern their assembly, stability, and functional contributions across environments.
Yizhu Qiao   +5 more
wiley   +1 more source

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