Results 101 to 110 of about 20,629 (261)

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

A horizontally transferred bacterial gene for pantothenic acid biosynthesis regulates diapause and reproduction in the spider mite Amphitetranychus viennensis

Insect Science, EarlyView.
A bacterial‐derived AvPBL gene encoding a pantothenate‐β‐alanine ligase was identified in Amphitetranychus viennensis. RNAi silencing of AvPBL reduced pantothenic acid production, impairing reproduction and diapause induction, while pantothenic acid supplementation rescued these phenotypes.
Meibin Liu, Yifei Wang, Yikang Ren, Fan Yang, Meifeng Ren, Qin Yu, Xuguo Zhou, Zezhong Yang, Jing Yang   +8 more
wiley   +1 more source

New Polyketides and a Ferroptosis Inhibitor from the Marine-Derived Fungus Diaporthe searlei CS-HF-1

Marine Drugs
As a driver of neurodegenerative disorders, ischemic injuries, and acute organ dysfunction, ferroptosis represents a therapeutic target, and its inhibition may provide novel therapies. In our ongoing efforts to discover ferroptosis inhibitors from fungal
Jicheng Xiao, Peng Wu, Yan Zhang, Qi Lv, Yulang Chi, Wei Xu, Wenzhen Lin, Zhongbin Cheng   +7 more
doaj   +1 more source

Response of Fecal Bacteria and Fungi to Tannin‐Rich Diets in Sika Deer (Cervus nippon): Evidence from Both Feeding Experiments and Field Investigations

Integrative Zoology, EarlyView.
Feeding with tannin‐rich diets altered the fecal microbial composition and increased the relative abundance of tannin‐degrading microbes. We hypothesize that fecal bacteria and fungi may play important roles in helping herbivores adapt to tannin‐rich diets but respond to different tannin concentrations varies.
Di Zhu, Feng Wu, Peiying Wen, Haiyang Gao, Xiaoran Hao, Hongfang Wang   +5 more
wiley   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Polyketides isolated from Penicillim herquei [PDF]

, 2011
In this work we are reporting the isolation of polyketides citreoserine (1), emodin (2), janthinone (3), dihydrocitrinone (4) and citrinin H-1 (5). The compounds were isolated by chromatographic procedures and identified by spectral methods of NMR 1D and
Andrey Moacir do Rosario Marinho, Edson Rodrigues Filho, RODRIGUES FILHO, Edson, FERREIRA, Izabel Cristina Piloto, MARINHO, Anderson Nonato do Rosario, Patrícia Santana Barbosa Marinho, Izabel Cristina Piloto Ferreira, MARINHO, Patrícia Santana Barbosa   +7 more
core   +1 more source

Seasonal Difference of Gut Microbiota at a Stopover Site in Five Passerines of Different Migratory Behavior

Integrative Zoology, EarlyView.
Seasonal variation significantly reshaped gut microbiota composition in migratory passerine species, whereas the resident species Suthora webbiana showed no clear seasonal shift. Species with similar migratory behaviors exhibited consistent seasonal patterns in their core gut microbiota.
Jundong Duan, Amina Tufail, Xiaoping Wang, Tingbei Bo, Na Zhao, Yifan Yue, Sandi Willows‐Munro, Yanhua Qu, Jianshi Jin, Fumin Lei, Chenxi Jia, Gang Song   +11 more
wiley   +1 more source

Polyketide Derivatives from the Mangrove-Derived Fungus Penicillium sp. HDN15-312

Marine Drugs
Four new polyketides, namely furantides A–B (1–2), talamin E (3) and arugosinacid A (4), and two known polyketides were obtained from the mangrove-derived fungus Penicillium sp. HDN15-312 using the One Strain Many Compounds (OSMAC) strategy.
Fuhao Liu, Wenxue Wang, Feifei Wang, Luning Zhou, Guangyuan Luo, Guojian Zhang, Tianjiao Zhu, Qian Che, Dehai Li   +8 more
doaj   +1 more source

Natural product‐derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges

British Journal of Pharmacology, EarlyView.
Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang, Hio Lam Ho, F. David Horgen, Andrea Fleig, Zhong‐Ping Feng, Hong‐Shuo Sun   +5 more
wiley   +1 more source

Two new aromatic polyketides from a sponge-derived Fusarium [PDF]

Two new aromatic polyketides from a sponge-derived ...
Radjasa, Ocky Karna, Zhou, Tao, Fukaya, Keisuke, Sabdono, Agus, Sibero, Mada T., Urabe, Daisuke, Trianto, Agus, Igarashi, yasuhiro   +7 more
core   +1 more source