Results 121 to 130 of about 19,197 (232)
Synthetic Studies Toward the Total Synthesis of Maklamicin and Related Spirotetronate Polyketides [PDF]
, 2016 Spirotetronate polyketides are naturally occurring natural products that are highlighted by their complex structures and intruiging biological activities.
Lacoske, Michelle
core
European Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.The intramolecular nitrile oxide olefin [3 + 2]‐cycloaddition offers a reliable entry toward 2‐aza‐bicyclo[4.3.0]‐nonanes, a substructure found in several bioactive piperidine alkaloids. The required oxime precursors were prepared in non‐racemic form by Ir‐catalyzed asymmetric allylation and ring‐closing metathesis.
Alicia Köcher +5 more
wiley +1 more source
A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling
Chemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug +2 more
wiley +1 more source
Biosynthesis of polyketides by two type III polyketide synthases from Aloe barbadensis
, 2019 Various bioactive polyketides have been found in Aloe barbadensis. However, the polyketide synthases (PKSs), which participate in biosynthesis of polyketides in A. barbadensis remain unknown.
Ji-Mei Liu (812942) +8 more
core +1 more source
Two new aromatic polyketides from a sponge-derived Fusarium [PDF]
Two new aromatic polyketides from a sponge-derived ...
Radjasa, Ocky Karna +7 more
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Polyketides isolated from Penicillim herquei
, 2011 In this work we are reporting the isolation of polyketides citreoserine (1), emodin (2), janthinone (3), dihydrocitrinone (4) and citrinin H-1 (5). The compounds were isolated by chromatographic procedures and identified by spectral methods of NMR 1D and
Andrey Moacir do Rosario Marinho +7 more
core +1 more source
New Polyketides and a Ferroptosis Inhibitor from the Marine-Derived Fungus Diaporthe searlei CS-HF-1
Marine DrugsAs a driver of neurodegenerative disorders, ischemic injuries, and acute organ dysfunction, ferroptosis represents a therapeutic target, and its inhibition may provide novel therapies. In our ongoing efforts to discover ferroptosis inhibitors from fungal
Jicheng Xiao +7 more
doaj +1 more source
, 2023 By analogy to keystone species, new theory proposes that compounds with disproportionate effects on ecosystems may be keystone molecules, regulating communities with outsized impacts relative to their abundance in the environment.
Nguyen, Helen
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Editorial: Innovators in chemical biology
Frontiers in Chemistry, 2022 John D. Wade +4 more
doaj +1 more source
MoleculesOne pair of novel enantiomers, gigantdioxin A (+)-1 and B (−)-1, with a skeleton of benzo[d][1,3]dioxin; a new acetophenone gigantone A (3); a known 3-chlorogentisyl alcohol (2), which is the bioprecursor of 1; acetophenone (4); and chromone derivative ...
Ying-Tong Lin +9 more
doaj +1 more source