Results 91 to 100 of about 20,629 (261)
Reimer C, Kufs JE, Rautschek J, Regestein L, Valiante V, Hillmann F. Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides. Nature Biotechnology.
Kufs, Johann E. ; https://orcid.org/ +5 more
core +1 more source
Overexpression of the gouM transporter gene in Streptomyces noursei CK‐15 enhances gougerotin production by 114% and activates silent biosynthetic gene clusters. This finding links transporter activity to metabolite efflux and secondary metabolism, offering a strategy for natural product discovery and strain optimization.
Qianying Zhou +6 more
wiley +1 more source
Prymnesins: Toxic Metabolites of the Golden Alga, Prymnesium parvum Carter (Haptophyta)
Increasingly over the past century, seasonal fish kills associated with toxic blooms of Prymnesium parvum have devastated aquaculture and native fish, shellfish, and mollusk populations worldwide. Protracted blooms of P.
John W. La Claire, Schonna R. Manning
doaj +1 more source
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
Total synthesis of elansolids B1 and B2
The elansolids A1–A3, B1, and B2 are secondary metabolites formed by the gliding bacterium Chitinophaga sancti. They show antibacterial activity against Gram-positive bacteria.
Liang-Liang Wang, Andreas Kirschning
doaj +1 more source
Novel polyketides isolated from Streptomyces sp.
From the endophytic strain Streptomyces sp. CS of Maytenus hookeri, five novel type III polyketides, compounds 1-5, were isolated. Their structures were elucidated by spectroscopic analyses including 1D- and 2D-NMR experiments, and by HR-ESI ...
鲁春华 +7 more
core +1 more source
This study highlights the biocontrol potential of Streptomyces strain Strep_22. In vitro, it inhibits key fungal pathogens by 91.52%. In vivo, it significantly reduces disease incidence in wheat and tomato while enhancing biomass, shoot, and root development, offering a highly promising, sustainable ecological alternative to chemical pesticides ...
Thomas Conte +6 more
wiley +1 more source
Rapid mining of large genomic and metagenomic data sets for modular polyketide synthases, non-ribosomal peptide synthetases and hybrid polyketide synthase/non-ribosomal peptide synthetase biosynthetic gene clusters has been achieved using the generic ...
Jurica Zucko +7 more
doaj
Tanzawaic acids I–L: Four new polyketides from Penicillium sp. IBWF104-06
Four new polyketides have been identified in culture filtrates of the fungal strain Penicillium sp. IBWF104-06 isolated from a soil sample. They are structurally based on the same trans-decalinpentanoic acid skeleton as tanzawaic acids A–H.
Louis P. Sandjo +3 more
doaj +1 more source
Polyketides are an important class of bioactive small molecules valued not only for their diverse therapeutic applications, but also for their role in controlling interesting biological phenotypes in their producing organisms.
Seong-Jong Kim +5 more
core +1 more source

