Results 91 to 100 of about 20,629 (261)

Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides

open access: yes, 2022
Reimer C, Kufs JE, Rautschek J, Regestein L, Valiante V, Hillmann F. Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides. Nature Biotechnology.
Kufs, Johann E. ; https://orcid.org/   +5 more
core   +1 more source

Impact of the GouM transporter on secondary metabolism activation and production yield in Streptomyces noursei strain CK‐15

open access: yesNew Plant Protection, EarlyView.
Overexpression of the gouM transporter gene in Streptomyces noursei CK‐15 enhances gougerotin production by 114% and activates silent biosynthetic gene clusters. This finding links transporter activity to metabolite efflux and secondary metabolism, offering a strategy for natural product discovery and strain optimization.
Qianying Zhou   +6 more
wiley   +1 more source

Prymnesins: Toxic Metabolites of the Golden Alga, Prymnesium parvum Carter (Haptophyta)

open access: yesMarine Drugs, 2010
Increasingly over the past century, seasonal fish kills associated with toxic blooms of Prymnesium parvum have devastated aquaculture and native fish, shellfish, and mollusk populations worldwide. Protracted blooms of P.
John W. La Claire, Schonna R. Manning
doaj   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

open access: yesPest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King   +6 more
wiley   +1 more source

Total synthesis of elansolids B1 and B2

open access: yesBeilstein Journal of Organic Chemistry, 2017
The elansolids A1–A3, B1, and B2 are secondary metabolites formed by the gliding bacterium Chitinophaga sancti. They show antibacterial activity against Gram-positive bacteria.
Liang-Liang Wang, Andreas Kirschning
doaj   +1 more source

Novel polyketides isolated from Streptomyces sp.

open access: yes, 2008
From the endophytic strain Streptomyces sp. CS of Maytenus hookeri, five novel type III polyketides, compounds 1-5, were isolated. Their structures were elucidated by spectroscopic analyses including 1D- and 2D-NMR experiments, and by HR-ESI ...
鲁春华   +7 more
core   +1 more source

Biocontrol and plant growth‐promoting potential of Streptomyces strains against fungal pathogens of tomato and wheat for a sustainable agriculture

open access: yesPest Management Science, EarlyView.
This study highlights the biocontrol potential of Streptomyces strain Strep_22. In vitro, it inhibits key fungal pathogens by 91.52%. In vivo, it significantly reduces disease incidence in wheat and tomato while enhancing biomass, shoot, and root development, offering a highly promising, sustainable ecological alternative to chemical pesticides ...
Thomas Conte   +6 more
wiley   +1 more source

From DNA Sequences to Chemical Structures – Methods for Mining Microbial Genomic and Metagenomic Data Sets for New Natural Products

open access: yesFood Technology and Biotechnology, 2010
Rapid mining of large genomic and metagenomic data sets for modular polyketide synthases, non-ribosomal peptide synthetases and hybrid polyketide synthase/non-ribosomal peptide synthetase biosynthetic gene clusters has been achieved using the generic ...
Jurica Zucko   +7 more
doaj  

Tanzawaic acids I–L: Four new polyketides from Penicillium sp. IBWF104-06

open access: yesBeilstein Journal of Organic Chemistry, 2014
Four new polyketides have been identified in culture filtrates of the fungal strain Penicillium sp. IBWF104-06 isolated from a soil sample. They are structurally based on the same trans-decalinpentanoic acid skeleton as tanzawaic acids A–H.
Louis P. Sandjo   +3 more
doaj   +1 more source

The industrial anaerobeClostridium acetobutylicumuses polyketides to regulate butanol production and differentiation

open access: yes, 2017
Polyketides are an important class of bioactive small molecules valued not only for their diverse therapeutic applications, but also for their role in controlling interesting biological phenotypes in their producing organisms.
Seong-Jong Kim   +5 more
core   +1 more source

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