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Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases
Nature, 1995Modular polyketide synthases (PKSs) are complex multi-enzyme proteins that catalyse the bacterial biosynthesis of many pharmaceutically useful polyketides. The PKSs are organized into a series of modules, each containing the active catalytic sites required for one step in the synthesis process.
R, Pieper, G, Luo, D E, Cane, C, Khosla
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Production of a novel polyketide through the construction of a hybrid polyketide synthase
Gene, 1996The lactone rings of the polyketides platenolide and tylactone are synthesized by condensation of acetate-, proprionate-, and butyrate-derived precursors. A hybrid tylactone/platenolide synthase was constructed to determine if the choice of substrate is programmed by the polyketide synthase and to ascertain if a substrate different than that normally ...
S, Kuhstoss +4 more
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ChemInform Abstract: Biosynthesis of Polyketides by trans‐AT Polyketide Synthases
ChemInform, 2010AbstractReview: 436 refs.
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New Polyketides from the Antarctic Fungus Pseudogymnoascus sp. HSX2#-11
Marine Drugs, 2021, Ting Shi, Shi Ting
exaly
Fungal Pigments: Carotenoids, Riboflavin, and Polyketides with Diverse Applications
Journal of Fungi (Basel, Switzerland), 2023Maria Afroz Toma +2 more
exaly