Results 41 to 50 of about 2,992,684 (345)
Drug Delivery, 2022 The systemic drug has historically been preferred for the treatment of the majority of pathological conditions, particularly liver cancer. Indeed, this mode of treatment is associated with adverse reactions, toxicity, off-target accumulation, and rapid ...
Jianyong Ma +6 more
doaj +1 more source
A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics.
Proceedings of the National Academy of Sciences of the United States of America, 1998 A unified view of polymer, dumbbell, and oligonucleotide nearest-neighbor (NN) thermodynamics is presented. DNA NN DeltaG degrees 37 parameters from seven laboratories are presented in the same format so that careful comparisons can be made.
Jr. John SantaLucia
semanticscholar +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Drug Delivery, 2022 The tremendous development of peptide-based cancer vaccine has attracted incremental interest as a powerful approach in cancer management, prevention and treatment.
Qiyan Wang +7 more
doaj +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Frontiers in Physics, 2022 Surface functionalization of polymers by chemically reactive oxygen is a standard technique for increasing the surface energy of polymers. The technique, however, usually does not provide the desired surface finish of many polymers, including highly ...
Rok Zaplotnik, Miran Mozetič
doaj +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Effect of subsoil moisture on filtration through a screen defect
Magazine of Civil Engineering, 2022 The aim of the scientific work is to study the features of filtration under a defect of a polymer screen made of a geomembrane, where the movement of the filtration flow occurs with incomplete saturation of the soil with water.
Baev Oleg +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
A Two-Ply Polymer-Based Flexible Tactile Sensor Sheet Using Electric Capacitance
Sensors, 2014 Traditional capacitive tactile sensor sheets usually have a three-layered structure, with a dielectric layer sandwiched by two electrode layers. Each electrode layer has a number of parallel ribbon-like electrodes.
Shijie Guo +3 more
doaj +1 more source