Results 61 to 70 of about 3,057,169 (381)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Adhesives: Polymer Chemistry at Work
CHIMIA, 2008 Successful adhesive technology relies on the diligent engineering of adhesive and cohesive forces. Polymers thereby play the dominant role as they largely determine the chemical and physical properties of the adhesive joint.
Christof Arz +4 more
doaj +1 more source
Can Polymer Coils be modeled as "Soft Colloids"? [PDF]
Phys. Rev. Lett. 85, 2522 (2000), 2000 We map dilute or semi-dilute solutions of non-intersecting polymer chains onto a fluid of ``soft'' particles interacting via a concentration dependent effective pair potential, by inverting the pair distribution function of the centers of mass of the initial polymer chains.
arxiv +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
iScience, 2020 Summary: Carbon-carbon bond formation through polarity reversal ketyl radical anion coupling of carbonyls has inspired new reaction modes to this cornerstone carbonyl group and played significant roles in organic chemistry.
Shun-Shun Li +5 more
doaj
General method to stabilize mesophilic proteins in hyperthermal water
iScience, 2021 Summary: The stability of protein structures and biological functions at normal temperature is closely linked with the universal aqueous environment of organisms.
Xiaoqian Xin +3 more
doaj
Understanding Segmental Dynamics in Polymer Electrolytes: A Computer Study [PDF]
Macromolecular Chemistry and Physics, Vol 208, Iss. 19-20, pg.
2215, 2007, 2008 We study the segmental dynamics of poly(ethylene oxide) (PEO) from microscopic simulations in the neat polymer and a polymer electrolyte (PEO/LiBF$_4$) by analyzing the normal modes. We verify the applicability of the Rouse theory, specifically for the polymer electrolyte where dynamic heterogeneities, arising from cation-polymer interactions, alter ...
arxiv +1 more source
David Sherrington commemorative issue [PDF]
, 2015 This themed issue of Polymer Chemistry was commissioned following the passing, in October 2014, of Professor David Colin Sherrington, FRS. It was commissioned as a dedication to the memory of a world-class polymer chemist of international renown, as well
Cormack, Peter A. G., Haddleton, David
core +1 more source
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Molecular Oncology, EarlyView.Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler +12 more
wiley +1 more source
Non-Markovian polymer reaction kinetics [PDF]
Nature Chemistry, 4, 568-573 (2012), 2012 Describing the kinetics of polymer reactions, such as the formation of loops and hairpins in nucleic acids or polypeptides, is complicated by the structural dynamics of their chains. Although both intramolecular reactions, such as cyclization, and intermolecular reactions have been studied extensively, both experimentally and theoretically, there is to
arxiv +1 more source