Impact of switching from polymerase chain reaction-only to two-step <i>Clostridioides difficile</i> testing in a large hospital system. [PDF]
Gupta SR +11 more
europepmc +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Clinical features of varicella-zoster virus meningitis diagnosed by polymerase chain reaction without abnormal routine cerebrospinal fluid analysis. [PDF]
Kitamura A +11 more
europepmc +1 more source
Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park +13 more
wiley +1 more source
Selection and evaluation of reference genes for quantitative real-time polymerase chain reaction normalization in Pieris melete (Lepidoptera, Pieridae). [PDF]
Jiang T +5 more
europepmc +1 more source
Macrophages Mediate Mesoscale Brain Mechanical Homeostasis
We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So +11 more
wiley +1 more source
Pre‐Vascularized hMSC and hPDC Spheroids as Building Block Units for Bone Tissue Engineering
This study presents the development of small pre‐vascularized spheroids composed of human mesenchymal stromal cells or periosteum‐derived progenitor cells with endothelial cells. These microtissues demonstrated enhanced osteogenic and angiogenic potential, particularly with periosteum‐derived cells, and hold promise as building blocks for vascularized ...
Filipa C. Teixeira +4 more
wiley +1 more source
Multiplex Polymerase Chain Reaction (PCR) and Conventional Methods for Diagnosing Ventilator-Associated Pneumonia in ICU Settings: A Systematic Review. [PDF]
Fadel Yosif AS +5 more
europepmc +1 more source

