Results 81 to 90 of about 250,640 (230)

Synthesis of Cross-Linked Polymeric Micelle pH Nanosensors: An Investigation of Design Flexibility

, 2015
The design flexibility that polymeric micelles offer in the fabrication of optical nanosensors for ratiometric pH measurements is investigated. pH nanosensors based on polymeric micelles are synthesized either by a mixed-micellization approach or by a ...
Andresen, Thomas Lars, Ek, Pramod Kumar, Jølck, Rasmus Irming   +2 more
core   +1 more source

A broadly applicable protein-polymer adjuvant system for antiviral vaccines

EMBO Molecular Medicine
Although protein subunit vaccines generally have acceptable safety profiles with precise antigenic content, limited immunogenicity can lead to unsatisfactory humoral and cellular immunity and the need for vaccine adjuvants and delivery system. Herein, we
Caiqian Wang, Yuanyuan Geng, Haoran Wang, Zeheng Ren, Qingxiu Hou, An Fang, Qiong Wu, Liqin Wu, Xiujuan Shi, Ming Zhou, Zhen F Fu, Jonathan F Lovell, Honglin Jin, Ling Zhao   +13 more
doaj   +1 more source

Bypassing Heteronuclear MRI: Metal‐Free Organosilicon Nanotracers for Background‐Free Hotspot 1H Imaging on Clinical Hardware

Advanced Science, EarlyView.
Organosilicon micelles enable background‐free molecular magnetic resonance imaging (MRI) while remaining fully compatible with standard proton (1H) hardware. By exploiting a spectrally silent 1H window at ∼0 ppm, the silicone nanotracer allows hotspot detection by 1H chemical‐shift imaging (CSI) without metals or heteronuclei, enabling direct overlay ...
Martin Orsagh, Dominik Havlicek, Andrea Galisova, Ondrej Sedlacek, Daniel Jirak   +4 more
wiley   +1 more source

Nanoparticle drug delivery systems: an excellent carrier for tumor peptide vaccines

Drug Delivery, 2018
In the past 40 years, the nanoparticle drug delivery system for tumor peptide vaccines has been widely studied which also reached a splendid result. Nanomaterial can enhance the targeting of vaccines, help vaccines enter the cells and trigger immune ...
Jiemin Wang, Xiongbin Hu, Daxiong Xiang
doaj   +1 more source

Triple‐Helix Biomolecules Construct Self‐Adaptive Multi‐Phase Interfaces for Dendrites Immunized Zinc Metal Anodes

Advanced Science, EarlyView.
A bio‐derived triple‐helix framework enables adaptive interphase engineering for aqueous Zn metal batteries. Directional Zn2+ migration channels and dynamic transformation into β‐sheet domains construct an optimized solid electrolyte interphase with flexible–rigid synergy, delivering dendrite‐free Zn deposition and exceptional long‐term battery cycling
Tianyi Wang, Jiahui Lu, Wei Gu, Jianfei Shi, Yuting Qin, Jian Yang, Di He, Zixia Lin, Jiabao Li, Bing Sun, Guoxiu Wang, Chengyin Wang   +11 more
wiley   +1 more source

Uptake of CDDP-containing Polymeric Micelle by Cells Using Particle Induced X-ray Emission

, 2010
Polymeric micelles loading cis-diamminedichloroplatinum(II), CDDP, (cisplatin micelle) has performed higher accumulation in solid tumors and lower toxicities compared to CDDP alone.
457985, Oikawa, Masakazu, 457986, 457976, 457987, 457977, 今関 等, 457978, 457979, Ishikawa, Takahiro, Uesaka, Mitsuru, Konishi, Teruaki, Iso, Hiroyuki, 石川 剛弘, Mizuno, Kazue, 及川 将一, Imaseki, Hitoshi, 磯 浩之, 小西 輝昭, 457980, 457981, 457982, 457983, 457984   +23 more
core   +1 more source

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Advanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang, Moon Sup Yoon, Jae Min Lee, Min Jeong Jo, Chae Eun Jin, Dae Hwan Shin   +5 more
wiley   +1 more source

Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: optimization and in vitro, in vivo evaluation

International Journal of Nanomedicine, 2013
Liangcen Chen, Xianyi Sha, Xinyi Jiang, Yanzuo Chen, Qiuyue Ren, Xiaoling FangDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, ChinaAbstract: The aim of this work was to establish a novel polymeric mixed micelle composed of ...
Fang X, Ren Q, Chen Y, Jiang X, Sha X, Chen L   +5 more
doaj  

Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins

Advanced Science, EarlyView.
Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller, Cheryl Hayashi, Thomas R. Scheibel   +2 more
wiley   +1 more source

Experimental Design, Synthesis and Application of Molecular Micelle Modified Polymeric Nanoparticles for Drug Delivery Systems and Free Radical Detection [PDF]

, 2009
Biodegradable and biocompatible polymeric nanoparticles such as poly (lactide-co-glycolide) (PLGA) nanoparticles have been extensively studied as drug delivery systems for a variety of pharmaceutical agents.
Ganea Visser, Gabriela M.
core   +1 more source