Results 221 to 230 of about 59,311 (300)

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform

open access: yesMacromolecular Rapid Communications, EarlyView.
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt   +6 more
wiley   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

open access: yesMacromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani   +6 more
wiley   +1 more source

Hydrogels Incorporating Donor–Acceptor Stenhouse Adducts as a Platform for Photoinduced, On‐Off Switchable Release of Small Molecule Cargos

open access: yesMacromolecular Rapid Communications, EarlyView.
Donor–acceptor Stenhouse aDdducts (DASAs) are known for their photoinduced tautomerization, which, when conjugated to block copolymers, can self‐assemble into tuneable polymersomes. These DASA‐polymersomes are being investigated for light‐controlled cargo release in biomedical applications.
Tristan N. Dell   +10 more
wiley   +1 more source

Doping‐Free Polymer Nanoparticle Engineering of n‐Type Organic Mixed Ion–Electron Conductors for Enhancement‐Mode Organic Electrochemical Transistors

open access: yesMacromolecular Rapid Communications, EarlyView.
We report a nanoparticle formulation strategy for the ladder polymer BBL that enables undoped enhancement‐mode OECTs. Controlled reprecipitation with DBSA yields stable nanoparticles, and spray‐coating forms dense, well‐connected films. The resulting devices exhibit strongly enhanced electrochemical response and transconductance, establishing a ...
Shunsuke Yamamoto   +2 more
wiley   +1 more source

Tunable polymeric micelles for taxane and corticosteroid co-delivery. [PDF]

open access: yesDrug Deliv Transl Res
Shalmani AA   +12 more
europepmc   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

open access: yesMacromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Enhancing the Oxygen Evolution Performance by Introducing NiO‐Supported Mesoporous Titanium Dioxide

open access: yesChemistryOpen, EarlyView.
Herein, a schematic representation of the synthesis of NiO‐supported mesoporous TiO2 is reported. The process involves self‐assembly of polyvinylpyrrolidone (PVP), Ti(acac)2, nickel salt, and ethanol, followed by solvent evaporation, thermal polymerization, and stepwise calcination under N2 (350 °C) and air (450 °C) to remove PVP and carbon, yielding ...
Abdulrahman Y. Alzahrani   +3 more
wiley   +1 more source

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