Results 31 to 40 of about 2,130,838 (296)
Biomedicines, 2022 Multifunctional fatty acid grafted polymeric micelles are an effective and promising approach for drug and gene delivery to the brain. An alternative approach to bypass the blood–brain barrier is administration through intranasal route.
Richard Nii Lante Lamptey +4 more
doaj +1 more source
Enzyme-Responsive Polymeric Micelles of Cabazitaxel for Prostate Cancer Targeted Therapy
Acta Biomaterialia, 2020 Cabazitaxel, a novel tubulin inhibitor with poor affinity for P-glycoprotein, is a second-generation taxane holding great promise for the treatment of metastatic castration-resistant prostate cancer.
Ashutosh J Barve +4 more
semanticscholar +1 more source
Nanomaterials, 2018 The compound 5’-deoxy-5-fluorouridine (5’-DFUR) is a prodrug of the anti-tumor drug 5-fluorouracil (5-FU). Thymidine phosphorylase (TP) is an enzyme that can convert 5’-DFUR to its active form 5-FU and the expression of TP is ...
Alicia J. Sawdon +3 more
doaj +1 more source
Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery.
Journal of Controlled Release, 2020 To avoid poly(ethylene glycol)-related issues of nanomedicines such as accelerated blood clearance, fully N-2-hydroxypropyl methacrylamide (HPMAm)-based polymeric micelles decorated with biotin for drug delivery were designed.
Yan Wang +6 more
semanticscholar +1 more source
Ars Pharmaceutica, 2020 Background: topical antiseptic agents have been used widely in normal skin and wound which is associated with side effects such as systemic toxicity. Objective: Iodine is a non-metallic agent with an antimicrobial property that is used in the clinic as ...
Behzad Sharif Makhmal Zadeh +1 more
doaj +1 more source
In vitro Anticancer Activity of Flaxseed Oil Loaded-Polymeric Micelles in Breast Cancer Cell Line [PDF]
Brazilian Archives of Biology and TechnologyPhytochemicals have emerged as potential anticancer agents for breast cancer treatment, which remains one of the most common cancer types today.
Eda Nur Yetiskin Morkan +5 more
doaj +2 more sources
PLoS ONE, 2019 Astaxanthin is a highly potent antioxidant which can be extracted from Haematococcus pluvialis when cultivated and induced at high stress conditions. Due to astaxanthin's hydrophobicity, methoxypolyethylene glycol-polycaprolactone (mPEG-PCL) copolymer ...
Jun Zhang, Ching-An Peng
doaj +1 more source
pH-responsive polymeric micelles self-assembled from amphiphilic copolymer modified with lipid used as doxorubicin delivery carriers [PDF]
Royal Society Open Science, 2018 In the present study, a novel pH-responsive amphiphilic copolymer, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)] conjugated poly(β-amino esters) (DSPE-b-PEG-b-PAE-b-PEG-b-DSPE), was designed and successfully synthesized
Xin Xin Zhou +3 more
doaj +1 more source
Polymeric-Micelle-Based Delivery Systems for Nucleic Acids
Pharmaceutics, 2023 Nucleic acids can modulate gene expression specifically. They are increasingly being utilized and show huge potential for the prevention or treatment of various diseases.
Genada Sinani +3 more
doaj +1 more source
Rational design of polymeric micelles for targeted therapeutic delivery
Nano TodayPolymeric micellar drug carriers have emerged as effective tools to enhance the solubility and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that facilitates their passive targeting in human tissues through their ...
Yuting Zheng +7 more
semanticscholar +1 more source