Results 31 to 40 of about 277,094 (244)

The reduction in iodine absorption through rat skin by polymeric micelles in comparison with Povidone-Iodine: an ex-vivo study

Ars Pharmaceutica, 2020
Background: topical antiseptic agents have been used widely in normal skin and wound which is associated with side effects such as systemic toxicity. Objective: Iodine is a non-metallic agent with an antimicrobial property that is used in the clinic as ...
Behzad Sharif Makhmal Zadeh, Mehrnoosh Bahmanpur   +1 more
doaj   +1 more source

In vitro Anticancer Activity of Flaxseed Oil Loaded-Polymeric Micelles in Breast Cancer Cell Line [PDF]

Brazilian Archives of Biology and Technology
Phytochemicals have emerged as potential anticancer agents for breast cancer treatment, which remains one of the most common cancer types today.
Eda Nur Yetiskin Morkan, Maria Daaboul, Shifa Alhamvi, Gulsah Akbas, Banu Mansuroglu, Murat Topuzogullari   +5 more
doaj   +2 more sources

Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles.

PLoS ONE, 2019
Astaxanthin is a highly potent antioxidant which can be extracted from Haematococcus pluvialis when cultivated and induced at high stress conditions. Due to astaxanthin's hydrophobicity, methoxypolyethylene glycol-polycaprolactone (mPEG-PCL) copolymer ...
Jun Zhang, Ching-An Peng
doaj   +1 more source

Polymeric micelles as cutaneous drug delivery system in normal skin and dermatological disorders

Journal of Advanced Pharmaceutical Technology & Research, 2018
The easy accessibility of skin made dermal application, one of the approaches for local drug therapy. Effectiveness of topical drug application is depended on different parameters such as skin barrier properties, physicochemical properties of drug and ...
Behzad Sharif Makhmalzade, Fateme Chavoshy   +1 more
doaj   +1 more source

pH-responsive polymeric micelles self-assembled from amphiphilic copolymer modified with lipid used as doxorubicin delivery carriers [PDF]

Royal Society Open Science, 2018
In the present study, a novel pH-responsive amphiphilic copolymer, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)] conjugated poly(β-amino esters) (DSPE-b-PEG-b-PAE-b-PEG-b-DSPE), was designed and successfully synthesized
Xin Xin Zhou, Long Jin, Rui Qun Qi, Teng Ma   +3 more
doaj   +1 more source

Polymeric-Micelle-Based Delivery Systems for Nucleic Acids

Pharmaceutics, 2023
Nucleic acids can modulate gene expression specifically. They are increasingly being utilized and show huge potential for the prevention or treatment of various diseases.
Genada Sinani, Meltem Ezgi Durgun, Erdal Cevher, Yıldız Özsoy   +3 more
doaj   +1 more source

Mitochondria-targeted and pH-triggered charge-convertible polymeric micelles for anticancer therapy

Materials & Design, 2022
Mitochondria-targeted and pH-triggered charge-convertible polymeric micelles (GPTD) were developed for doxorubicin (DOX) delivery and targeted anticancer therapy.
Lingli Jin, Yanwen Xu, Fengjiao Chen, Dingle Yu, Hongze Liang, Zhenjiang Liang, Ziyu Liu, Dr, Haiyan Li, Junying Liu, Hui Tan, Lingling Zhao   +10 more
doaj   +1 more source

Tumor Microenvironment-Responsive Drug Delivery Based on Polymeric Micelles for Precision Cancer Therapy: Strategies and Prospects

Biomedicines
In clinical practice, drug therapy for cancer is still limited by its inefficiency and high toxicity. For precision therapy, various drug delivery systems, including polymeric micelles self-assembled from amphiphilic polymeric materials, have been ...
Zhu Jin, Majdi Al Amili, Shengrong Guo
doaj   +1 more source

Preparation and optimization of polymeric micelles as an oral drug delivery system for deferoxamine mesylate: in vitro and ex vivo studies

Research in Pharmaceutical Sciences, 2019
Deferoxamine mesylate (DFO) is administered as a slow subcutaneous or intravenous infusion due to its poor oral bioavailability and lack of dose proportionality.
Anayatollah Salimi, Behzad Sharif Makhmal Zadeh, Moloud Kazemi   +2 more
doaj   +1 more source

Complex Polymeric Architectures Self-Assembling in Unimolecular Micelles: Preparation, Characterization and Drug Nanoencapsulation

Pharmaceutics, 2018
Unimolecular polymeric micelles are a class of single-molecule amphiphilic core-shell polymeric architectures, where the hydrophobic core is well stabilized by the hydrophilic shell, avoiding intermolecular core-core interactions.
Stefania Ordanini, Francesco Cellesi
doaj   +1 more source