Results 21 to 30 of about 2,130,838 (296)

Hypoxia-Responsive Polymeric Micelles for Enhancing Cancer Treatment

open access: yesFrontiers in Chemistry, 2020
Polymeric drug vectors have shown great potentials in cancer therapy. However, intelligent controlled release of drugs has become a major challenge in nanomedicine research.
Huayang Feng   +8 more
doaj   +1 more source

Characterizing the Drug-Release Enhancement Effect of Surfactants on Megestrol-Acetate-Loaded Granules

open access: yesPharmaceuticals, 2022
In this study, the effect of Cremophor® RH 40 (CR 40) classic micelles and Soluplus® (SP) polymeric micelles were investigated on a novel granule-type drug-delivery system containing megestrolacetate (MGA).
Gábor Katona   +4 more
doaj   +1 more source

Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy

open access: yesNanoscale Research Letters, 2020
Oleanolic acid has been used only as a subsidiary agent in cosmetic products. The aim of the study is to show the effect of oleanolic acid as an active ingredient for the alleviation of wrinkles in humans and to develop a polymeric micelle formulation ...
Joo Young An   +6 more
doaj   +1 more source

A Co-delivery System Based on a Dimeric Prodrug and Star-Shaped Polymeric Prodrug Micelles for Drug Delivery

open access: yesFrontiers in Chemistry, 2021
Chemotherapy is one of the commonly used therapies for the treatment of malignant tumors. Insufficient drug-loading capacity is the major challenge for polymeric micelle–based drug delivery systems of chemotherapy.
Man Zhou   +11 more
doaj   +1 more source

Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine

open access: yesPharmaceuticals, 2023
Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical settings for their potential as nanomedicines.
Qi Wang   +3 more
doaj   +1 more source

Polymeric Micelles for the Delivery of Poorly Soluble Drugs: from Nanoformulation to Clinical Approval

open access: yesAdvanced Drug Delivery Reviews, 2020
Over the last three decades, polymeric micelles have emerged as a highly promising drug delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules with high potency and significant toxicity were encapsulated in polymeric ...
Duhyeong Hwang   +2 more
semanticscholar   +1 more source

Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2022
In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging.
Nicole Lecot   +7 more
doaj   +1 more source

Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery

open access: yesNanomaterials, 2021
Four-arm star-shaped (denoted as ‘S’) polymer adamantane-[poly(lactic-co-glycolic acid)-b-poly(N,N’-diethylaminoethyl methacrylate) poly(ethylene glycol) monomethyl ether]4 (S-PLGA-D-P) and its linear (denoted as ‘L’) counterpart (L-PLGA-D-P) were ...
Weiqiu Wen, Chong Guo, Jianwei Guo
doaj   +1 more source

Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region

open access: yesPharmaceutics, 2021
Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula   +8 more
doaj   +1 more source

Synthesis of pH-Sensitive and Self-Fluorescent Polymeric Micelles Derived From Rosin and Vegetable Oils via ATRP

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Preparation and application of sustainable polymers derived from renewable resources are of great significance. The aim of this study is to synthesize a kind of sustainable polymeric micelles from rosin and vegetable oils via atom transfer radical ...
Juan Yu   +8 more
doaj   +1 more source

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