Results 21 to 30 of about 277,094 (244)

Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2022
In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging.
Nicole Lecot, Gonzalo Rodríguez, Valentina Stancov, Marcelo Fernández, Mercedes González, Romina J. Glisoni, Pablo Cabral, Hugo Cerecetto   +7 more
doaj   +1 more source

Enhancement of dissolution and oral bioavailability of lacidipine via pluronic P123/F127 mixed polymeric micelles: formulation, optimization using central composite design and in vivo bioavailability study

Drug Delivery, 2018
This study aims at preparing and optimizing lacidipine (LCDP) polymeric micelles using thin film hydration technique in order to overcome LCDP solubility-limited oral bioavailability. A two-factor three-level central composite face-centered design (CCFD)
Ahmed R. Fares, Aliaa N. ElMeshad, Mohamed A. A. Kassem   +2 more
doaj   +1 more source

Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region

Pharmaceutics, 2021
Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula, Amir Sadeghi Boroujeni, Shoupeng Cao, Shirin Tavakoli, Roxane Ridolfo, Elisa Toropainen, Marika Ruponen, Jan C. M. van Hest, Arto Urtti   +8 more
doaj   +1 more source

Self-assembly of multi-component fluorescent molecular logic gates in micelles [PDF]

, 2016
A recent strategy for developing supramolecular logic gates in water is based on combinations of molecules via self-assembly with surfactants, which eliminates the need for time-consuming synthesis. The self-assembly of surfactants and lumophores and
Magri, David C., Costa, Paola F. da, Paterson, Kyle A.   +2 more
core   +1 more source

Synthesis of pH-Sensitive and Self-Fluorescent Polymeric Micelles Derived From Rosin and Vegetable Oils via ATRP

Frontiers in Bioengineering and Biotechnology, 2021
Preparation and application of sustainable polymers derived from renewable resources are of great significance. The aim of this study is to synthesize a kind of sustainable polymeric micelles from rosin and vegetable oils via atom transfer radical ...
Juan Yu, Juan Yu, Chaoqun Xu, Chuanwei Lu, Chuanwei Lu, Qian Liu, Jifu Wang, Fuxiang Chu, Fuxiang Chu   +8 more
doaj   +1 more source

Grafted block complex coacervate core micelles and their effect on protein adsorption on silica and polystyrene [PDF]

, 2010
peer reviewedWe have studied the formation and the stability of grafted block complex coacervate core micelles (C3Ms) in solution and the influence of grafted block C3M coatings on the adsorption of the proteins beta-lactoglobulin, bovine serum albumin ...
Arie de Keizer, Cohen Stuart, Martien A., Brzozowska, Agata M., Norde, Willem, Christophe Detrembleur, Detrembleur, Christophe, Cohen Stuart, M.A., Agata M. Brzozowska, Willem Norde, de Keizer, Arie, Keizer, A., de, Stuart, Martien Cohen, Norde, W., Brzozowska, A.M., Detrembleur, C., Martien A. Cohen Stuart, de Keizer, A.   +16 more
core   +2 more sources

Loading Dependent Structural Model of Polymeric Micelles by Solid-State NMR [PDF]

, 2019
Physically loaded polymeric micelles - from bulk properties to a molecular level understanding: In this work, solid-state NMR complemented by PXRD and quantum chemical calculations is used to learn about the short range order and structural arrangement ...
Johannes, Wiest, Lorenz, Meinel, Michael M, Lübtow, Jonas, Schlauersbach, Ann-Christin, Pöppler, Robert, Luxenhofer   +5 more
core   +1 more source

Synthesis and Characterization of Fatty Acid Grafted Chitosan Polymeric Micelles for Improved Gene Delivery of VGF to the Brain through Intranasal Route

Biomedicines, 2022
Multifunctional fatty acid grafted polymeric micelles are an effective and promising approach for drug and gene delivery to the brain. An alternative approach to bypass the blood–brain barrier is administration through intranasal route.
Richard Nii Lante Lamptey, Avinash Gothwal, Riddhi Trivedi, Sanjay Arora, Jagdish Singh   +4 more
doaj   +1 more source

Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation [PDF]

, 2014
Co-crystallization of polymers with different configurations/tacticities provides access to materials with enhanced performance. The stereocomplexation of isotactic poly(L-lactide) and poly(D-lactide) has led to improved properties compared with each ...
Wilson, Neil R., Dyson, M.A., Schiller, Tara L, Dove, Andrew P., Schiller, T.L., Schiller, Tara, Dyson, M Adam, Sanchez, A.M., Sun, Liang, O'Reilly, R.K., Wilson, Neil R, Pitto-Barry, Anaïs, Schiller, Tara L., Kirby, Nigel, Sloan, Jeremy, Dyson, Mark Adam, Sun, L., O'Reilly, Rachel K; id_orcid, O'Reilly, Rachel K, Sloan, J., O’Reilly, Rachel K., Dove, Andrew P, Sanchez, Ana M., Kirby, N., Wilson, N.R., Dove, A.P., Sanchez, Ana M   +26 more
core   +1 more source

Enhanced Anticancer Activity of 5’-DFUR-PCL-MPEG Polymeric Prodrug Micelles Encapsulating Chemotherapeutic Drugs

Nanomaterials, 2018
The compound 5’-deoxy-5-fluorouridine (5’-DFUR) is a prodrug of the anti-tumor drug 5-fluorouracil (5-FU). Thymidine phosphorylase (TP) is an enzyme that can convert 5’-DFUR to its active form 5-FU and the expression of TP is ...
Alicia J. Sawdon, Jun Zhang, Xutu Wang, Ching-An Peng   +3 more
doaj   +1 more source