Results 11 to 20 of about 333,924 (199)
International Journal of Nanomedicine, 2011 Young-Il Jeong1,*, Do Hyung Kim1,2,*, Chung-Wook Chung1, Jin-Ju Yoo1, Kyung Ha Choi1, Cy Hyun Kim1,2, Seung Hee Ha1, Dae Hwan Kang1,2 1National Research and Development Center for Hepatobiliary Cancer, Pusan National University Yangsan Hospital, Yangsan,
Jeong YI +7 more
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Multifunctional Polymeric Micelles for Cancer Therapy
Polymers, 2022 Polymeric micelles, nanosized assemblies of amphiphilic polymers with a core–shell architecture, have been used as carriers for various therapeutic compounds. They have gained attention due to specific properties such as their capacity to solubilize poorly water-soluble drugs, biocompatibility, and the ability to accumulate in tumor via enhanced ...
Geun-Woo Jin +2 more
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Polymeric micelles for acyclovir drug delivery [PDF]
Colloids and Surfaces B: Biointerfaces, 2014 Polymeric prodrug micelles for delivery of acyclovir (ACV) were synthesized. First, ACV was used directly to initiate ring-opening polymerization of ɛ-caprolactone to form ACV-polycaprolactone (ACV-PCL). Through conjugation of hydrophobic ACV-PCL with hydrophilic methoxy poly(ethylene glycol) (MPEG) or chitosan, polymeric micelles for drug delivery ...
Alicia J, Sawdon, Ching-An, Peng
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Mixed Polymeric Micelles for Rapamycin Skin Delivery
Pharmaceutics, 2022 Facial angiofibromas (FA) are one of the most obvious cutaneous manifestations of tuberous sclerosis complex. Topical rapamycin for angiofibromas has been reported as a promising treatment. Several types of vehicles have been used hitherto, but polymeric
Guillaume Le Guyader +8 more
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Polymeric Micelles in Cancer Immunotherapy [PDF]
Molecules, 2021 Cancer immunotherapies have generated some miracles in the clinic by orchestrating our immune system to combat cancer cells. However, the safety and efficacy concerns of the systemic delivery of these immunostimulatory agents has limited their application.
Zhuoya Wan +7 more
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Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine
Pharmaceuticals, 2023 Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical settings for their potential as nanomedicines.
Qi Wang +3 more
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Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia [PDF]
, 2012 This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfluidic approach.
Carugo, D +21 more
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Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging.
Nicole Lecot +7 more
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Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery
Nanomaterials, 2021 Four-arm star-shaped (denoted as ‘S’) polymer adamantane-[poly(lactic-co-glycolic acid)-b-poly(N,N’-diethylaminoethyl methacrylate) poly(ethylene glycol) monomethyl ether]4 (S-PLGA-D-P) and its linear (denoted as ‘L’) counterpart (L-PLGA-D-P) were ...
Weiqiu Wen, Chong Guo, Jianwei Guo
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Drug Delivery, 2018 This study aims at preparing and optimizing lacidipine (LCDP) polymeric micelles using thin film hydration technique in order to overcome LCDP solubility-limited oral bioavailability. A two-factor three-level central composite face-centered design (CCFD)
Ahmed R. Fares +2 more
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