Results 11 to 20 of about 2,130,838 (296)

Nose-to-brain administration of cannabidiol-loaded polymeric micelles improves the core behavioral symptoms of autism spectrum disorder [PDF]

Bioactive Materials
Neurodevelopmental disorders including autism spectrum disorder (ASD) affect 5.9% of the global population. Research shows the potential therapeutic use of cannabidiol (CBD) to treat different neurodevelopmental disorders, including ASD.
Rania Awad, Shlomit Aga-Mizrachi, Inon Maoz, Lilach Simchi, Avi Avital, Alejandro Sosnik   +5 more
doaj   +2 more sources

Polymeric Micelles: Morphology, Synthesis, and Pharmaceutical Application [PDF]

E3S Web of Conferences, 2021
Polymeric micelles (PMs) are nanosized core-shell molecules formed by the self-assembly of amphiphilic block copolymers. Their unique morphologies, biocompatibility have allowed them to serve as drug carriers and have found wide applications in the ...
Bai Kun, Wang Anda
doaj   +1 more source

Polymeric Micelles in Cancer Immunotherapy [PDF]

Molecules, 2021
Cancer immunotherapies have generated some miracles in the clinic by orchestrating our immune system to combat cancer cells. However, the safety and efficacy concerns of the systemic delivery of these immunostimulatory agents has limited their application.
Zhuoya Wan, Ruohui Zheng, Pearl Moharil, Yuzhe Liu, Jing Chen, Runzi Sun, Xu Song, Qiang Ao   +7 more
openaire   +3 more sources

Amphiphilic Block Copolymers: Their Structures, and Self-Assembly to Polymeric Micelles and Polymersomes as Drug Delivery Vehicles

Polymers, 2022
Self-assembly of amphiphilic block copolymers display a multiplicity of nanoscale periodic patterns proposed as a dominant tool for the ‘bottom-up’ fabrication of nanomaterials with different levels of ordering.
K. Kuperkar, Dhruvi Patel, L. Atanase, P. Bahadur   +3 more
semanticscholar   +1 more source

Progress in Polymeric Micelles for Drug Delivery Applications

Pharmaceutics, 2022
Polymeric micelles (PMs) have made significant progress in drug delivery applications. A robust core–shell structure, kinetic stability and the inherent ability to solubilize hydrophobic drugs are the highlights of PMs.
S. Kotta, H. Aldawsari, S. M. Badr-Eldin, Anroop B Nair, Kamal Yt   +4 more
semanticscholar   +1 more source

Enhanced thermodynamic, pharmacokinetic and theranostic properties of polymeric micelles via hydrophobic core-clustering of superparamagnetic iron oxide nanoparticles

Biomaterials Research, 2022
Background Superparamagnetic iron oxide nanoparticles (SPIO) have been applied for decades to design theranostic polymeric micelles for targeted cancer therapy and diagnostic MR imaging. However, the effects of SPIO on the physicochemical, and biological
Yixin Jiang, Junghan Lee, Jin-Myung Seo, Enkhzaya Davaa, Kyung-Ju Shin, Su-Geun Yang   +5 more
doaj   +1 more source

Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles

Nature Biomedical Engineering, 2022
Intragastrically delivered polymeric micelles releasing butyrate along the intestinal tract restore barrier-protective responses in mouse models of peanut allergy and colitis.
Ruyi Wang, Shijie Cao, M. H. Bashir, Lauren A. Hesser, Yanlin Su, Sung Min Choi Hong, Andrew Thompson, Elliot Culleen, Matthew Sabados, N. Dylla, Evelyn Campbell, R. Bao, Eric B. Nonnecke, C. Bevins, D. Wilson, J. Hubbell, C. Nagler   +16 more
semanticscholar   +1 more source

Drug-Dependent Morphological Transitions in Spherical and Worm-Like Polymeric Micelles Define Stability and Pharmacological Performance of Micellar Drugs

bioRxiv, 2021
Significant advances in physicochemical properties of polymeric micelles enable optimization of therapeutic drug efficacy, supporting nanomedicine manufacturing and clinical translation.
Chaemin Lim, Jacob D. Ramsey, Duhyeong Hwang, S. Teixeira, C. Poon, J. Strauss, E. Rosen, M. Sokolsky-Papkov, A. Kabanov   +8 more
semanticscholar   +1 more source

Polymeric Micelles: A Promising Pathway for Dermal Drug Delivery

Materials, 2021
Nanotechnology is an area in great development and with application in the most varied fields of science, including cosmetic and pharmaceutical industries.
Ana Parra, I. Jarak, Ana Santos, F. Veiga, A. Figueiras   +4 more
semanticscholar   +1 more source

Intracellular K+-Responsive Block Copolymer Micelles for Targeted Drug Delivery of Curcumin

Frontiers in Bioengineering and Biotechnology, 2022
Curcumin (CUR) is a natural bioactive compound that has attracted attention as a “golden molecule” due to its therapeutic properties against several types of tumors.
Mingyue Jiang, Mingyue Jiang, Le Chen, Le Chen, Bo Chen, Qinghua Yu, Qinghua Yu, Xianming Zhang, Xianming Zhang, Weihong Jing, Weihong Jing, Limei Ma, Limei Ma, Tao Deng, Tao Deng, Zhangyou Yang, Zhangyou Yang, Chao Yu, Chao Yu, Chao Yu   +19 more
doaj   +1 more source