Results 81 to 90 of about 437,245 (314)
Polymers, 2023 An amazing variety of polymerization mechanisms enables the creation of polymers with given microstructures and comonomer sequences [...]
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Study of Ziegler-Natta/(2-PhInd)2ZrCl2 hybrid catalysts performance in slurry propylene polymerization [PDF]
Polyolefins Journal, 2015 Several types of hybrid catalysts are made through mixing of 4th generation Ziegler-Natta (ZN) and (2-PhInd)2ZrCl2 metallocene catalysts using triethylaluminum (TEA) as coupling agent.
Gholam-Reza Nejabat +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Polymerization of isobutylene using a new type of catalyst system [PDF]
, 2013 We studied isobutylene polymerization in the presence and/or absence of Phillips type catalyst. Phillips type catalyst (Chromium on silica surface) was activated under oxygen flow at 600oC.
George-Dawodu, Emmanuel Olumide
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Polymerization-Induced Hierarchical Electrostatic Self-Assembly: Scalable Synthesis of Multicompartment Polyion Complex Micelles and Their Monolayer Colloidal Nanosheets and Nanocages [PDF]
, 2020 Scalable synthesis of multicompartment polyion complex (PIC) systems has been achieved via visible light-initiated RAFT polymerization of cationic monomer in the presence of anionic diblock copolymer micelles in water at 25 °C.
Yuanli Cai +13 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Polymerization-Induced Nanostructural Transitions Driven by In Situ Polymer Grafting [PDF]
, 2018 Polymerization-induced structural transitions have gained attention recently due to the ease of creating and modifying nanostructured materials with controlled morphologies and length scales.
Robert J. Hickey (550809) +3 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source