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Polymorphism of clarithromycin
Archives of Pharmacal Research, 2000It is well recognized that physicochemical properties of drugs are affected by the type of polymorphic crystalline form of drugs. Clarithromycin is known to exist in at least three polymorphic crystalline forms. Since conventional means to obtain the most thermodynamically stable form (Form II) for the antibiotics is known to be associated with a low ...
Y T, Sohn, J K, Rhee, W B, Im
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Journal of Theoretical Biology, 1993
It is well known that for a single, autosomal locus with differential viabilities convergence to a stable equilibrium is assured. However if new alleles are introduced sequentially by mutation the final equilibrium may depend on the particular sequence. Thus the equilibrium to which the population moves will be randomly determined.
C, Cannings, J P, Tyrer, G T, Vickers
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It is well known that for a single, autosomal locus with differential viabilities convergence to a stable equilibrium is assured. However if new alleles are introduced sequentially by mutation the final equilibrium may depend on the particular sequence. Thus the equilibrium to which the population moves will be randomly determined.
C, Cannings, J P, Tyrer, G T, Vickers
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2005
Compression is an economical and efficient way of data handling in not only communication, but also storage purposes. We aimed to implement a compression application based on frequent use of English letters, digraphs, trigraphs and tetragraphs without sacrificing memory and/or the other resources.
Umit Topaloglu, Coskun Bayrak
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Compression is an economical and efficient way of data handling in not only communication, but also storage purposes. We aimed to implement a compression application based on frequent use of English letters, digraphs, trigraphs and tetragraphs without sacrificing memory and/or the other resources.
Umit Topaloglu, Coskun Bayrak
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Journal of Pharmaceutical Sciences, 1972
An evaluation of entropies and enthalpies of transition and fusion and a comparison of X-ray diffraction patterns and IR spectra of polymorphic forms of structurally related compounds were undertaken to obtain information which might prove useful in correlating the frequency of occurrence of polymorphism with certain aspects of chemical structure ...
S S, Yang, J K, Guillory
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An evaluation of entropies and enthalpies of transition and fusion and a comparison of X-ray diffraction patterns and IR spectra of polymorphic forms of structurally related compounds were undertaken to obtain information which might prove useful in correlating the frequency of occurrence of polymorphism with certain aspects of chemical structure ...
S S, Yang, J K, Guillory
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Acta Crystallographica Section C Crystal Structure Communications, 1996
The title compound, 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diyl diacetate, C21H23NO5, was crystallized from a solution of its hydrochloride and sodium acetate. Unlike prior reports in which crystals were hexagonal shaped (orthorhombic) and in space group P2(1)2(1)2(1), the crystals in the present determination grew as large prisms (monoclinic ...
J R, Deschamps +2 more
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The title compound, 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diyl diacetate, C21H23NO5, was crystallized from a solution of its hydrochloride and sodium acetate. Unlike prior reports in which crystals were hexagonal shaped (orthorhombic) and in space group P2(1)2(1)2(1), the crystals in the present determination grew as large prisms (monoclinic ...
J R, Deschamps +2 more
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Journal of Pharmaceutical Sciences, 1989
As the solubility in water of the cytotoxic drug estramustine is less than 1 mg/L, polymorphism can have an impact on the bioavailability of orally administered drug. Therefore, the solid state characteristics of estramustine samples, crystallized from different solvents, were investigated by means of X-ray crystallography, thermal analysis, and IR ...
T, Wadsten, N O, Lindberg
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As the solubility in water of the cytotoxic drug estramustine is less than 1 mg/L, polymorphism can have an impact on the bioavailability of orally administered drug. Therefore, the solid state characteristics of estramustine samples, crystallized from different solvents, were investigated by means of X-ray crystallography, thermal analysis, and IR ...
T, Wadsten, N O, Lindberg
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2005
We describe a polymorphic extension of the substructural lambda calculus αλ associated with the logic of bunched implications. This extension is particularly novel in that both variables and type variables are treated substructurally, being maintained through a system of zoned, bunched contexts.
Matthew Collinson +2 more
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We describe a polymorphic extension of the substructural lambda calculus αλ associated with the logic of bunched implications. This extension is particularly novel in that both variables and type variables are treated substructurally, being maintained through a system of zoned, bunched contexts.
Matthew Collinson +2 more
openaire +1 more source