Proceedings of the Royal Society of London. Series B. Biological Sciences, 2020 The title of this Symposium ‘From Mendel’s factors to the genetic code’ emphasizes a single aspect of genetic research. That is unfortunate in a subject of such wide scope. Even in the most general terms, it naturally involves far more than analysing the
E. Ford
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Loss-of-function variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi-ethnic Asian cohort [PDF]
Clinical and Molecular Hepatology, 2021 Background/Aims 17β-hydroxysteroid dehydrogenase 13 (HSD17B13) variants were recently reported to have significantly lower odds of non-alcoholic fatty liver disease (NAFLD).
Yi-Wen Ting +7 more
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Association of VDR gene ApaI polymorphism with obesity in Iranian population
Biomédica: revista del Instituto Nacional de Salud, 2021 Introduction: Identifying obesity risk factors as a health problem facing communities is crucial given its complexity. The vitamin D receptor gene has been reported as a possible cause of this disease.
Farzad Rashidi, Maryam Ostadsharif
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Association of Factor II G20210A, Factor V G1691A and methylenetetrahydrofolate reductase C677T gene polymorphism with different forms of myocardial infarction: ST segment elevation and non-ST segment elevation [PDF]
Vojnosanitetski Pregled, 2020 Background/Aim. Coagulation Factor II G20210A and Factor V G1691A variants are moderately associated with coronary artery disease. Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene C677T is associated with myocardial infarction (MI) in ...
Ćućuz-Jokić Milica +4 more
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Genome-wide association study of mitochondrial DNA in Chinese men identifies seven new susceptibility loci for high-altitude pulmonary oedema [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. High-altitude pulmonary oedema (HAPE), which normally occurs at altitudes higher than 3,000 m, is a potentially fatal disease due to hypoxia.
Tang Caizhi +4 more
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Forensic Application of ForenSeqTM DNA Signature Prep Kit in Zhengjiang She Ethnic Group
Fayixue Zazhi, 2021 ObjectiveTo evaluate the ability of the ForenSeqTM DNA Signature Prep kit （ForenSeq kit） in analyzing the sequence information of STRs in Zhejiang She ethnic group and its forensic application efficacy.MethodsA total of 50 Zhejiang She ethnic group ...
QU Yi-ling +12 more
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Genetic Polymorphism of 16 X-STR Loci in Xinjiang Uygur Population
Fayixue Zazhi, 2022 ObjectiveTo study the genetic polymorphism and population genetic parameters of 16 X-STR loci in Xinjiang Uygur population.MethodsThe Goldeneye® DNA identification system 17X was used to amplify 16 X-STR loci in 502 unrelated individuals （251 females and
YUAN Chun-yan +10 more
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Association of Combined TCF7L2 and KCNQ1 Gene Polymorphisms with Diabetic Micro- and Macrovascular Complications in Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2021 Background Vascular complications are the major morbid consequences of type 2 diabetes mellitus (T2DM). The transcription factor 7-like 2 (TCF7L2), potassium voltage-gated channel subfamily Q member 1 (KCNQ1), and inwardly-rectifying potassium channel ...
Rujikorn Rattanatham +7 more
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Alimentary Pharmacology and Therapeutics, 2020 Single nucleotide polymorphism–based genetic risk scores (GRS) model genetic risk as a continuum and can discriminate coeliac disease but have not been validated in clinic. Human leukocyte antigen (HLA) DQ gene testing is available in clinic but does not
S. Sharp +12 more
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Association of prothrombin, FV Leiden and MTHFR gene polymorphisms in the Montenegrin patients with venous thromboembolism [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Polymorphisms of the factor V Leiden (FV G1691A), prothrombin (FII G20210A), and methylene-tetrahydrofolate reductase (MTHFR C677T) genes are the most commonly investigated inherited risk factors for developing venous thromboembolism (VTE)
Teofilov Slađana +4 more
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