Results 1 to 10 of about 70 (70)
Polymorphism of Genetic Ambigrams [PDF]
Virus Evolution, 2021 AbstractDouble synonyms in the genetic code can be used as a tool to test competing hypotheses regarding ambigrammatic narnavirus genomes. Applying the analysis to recent observations ofCulex narnavirus 1andZhejiang mosquito virus 3ambigrammatic viruses indicates that the open reading frame on the complementary strand of the segment coding for RNA ...
Gytis Dudas +3 more
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Genetic Polymorphisms in Pharmaceuticals and Chemotherapy
World Journal of Oncology, 2021 The study of genetic polymorphisms has significantly advanced the field of personalized medicine. Polymorphism of genes influence the efficacy of drugs used for treating medical conditions such as depression, cardiac diseases, thromboembolic disorders, oncological diseases, etc. The study of genetic polymorphism is beneficial for drug safety as well as
Achuta Kumar Guddati +1 more
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Migraine and Genetic Polymorphisms: An Overview [PDF]
The Open Neurology Journal, 2012 The relationship between genetic polymorphisms and migraine as a cause of an increased risk of thrombotic disorders development is still debated In this respect, factor V Leiden, factor V (H1299R), prothrombin G20210A, factor XIII (V34L), β-fibrinogen, MTHFR (C677T), MTHFR (A1298C), APO E, PAI-1, HPA-1 and ACE I/D seem to play a determinant role in ...
V. Pizza +6 more
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Genetic polymorphisms in sepsis
Pediatric Critical Care Medicine, 2005 Wide variability exists in the susceptibility to and outcome from sepsis even within similar intensive care unit populations. Some of this variability in the host may be due to genetic variation in genes coding for components of the innate immune response.To review the evidence for a genetic influence on the susceptibility to and outcome from sepsis ...
Michael W. Quasney +3 more
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Genetic polymorphisms and folate status [PDF]
Congenital Anomalies, 2017 AbstractModerate hyperhomocysteinemia‐induced low folate status is an independent risk factor for cardiovascular disease, dementia, and depression. Folate is an essential cofactor in the one‐carbon metabolism pathway and is necessary in amino acid metabolism, purine and thymidylate synthesis, and DNA methylation.
Mami Hiraoka, Yasuo Kagawa
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Genetic Polymorphisms and Posttraumatic Complications [PDF]
Comparative and Functional Genomics, 2010 Major trauma is the leading cause of death in young adults. Despite advances in prehospital system and treatment in hospital, mortality rates have not improved significantly over the past decades. Victims of severe injuries who survive the initial hours have great risk for additional life-threatening complicaitons, including uncontrollable infection ...
Jianxin Jiang, Wei Gu
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Genetic polymorphisms and heart failure [PDF]
Genetics in Medicine, 2004 Heart failure is a complex clinical syndrome. There is evidence for a genetic contribution to the pathophysiology of heart failure. Considering the fundamental role of neurohormonal factors in the pathophysiology and progression of cardiac dysfunction and hypertrophy, variants of genes involved in this system are logical candidate genes in heart ...
Bruno H. Stricker +5 more
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Genetic polymorphisms in Afghanistan
Annals of Human Biology, 1977 The gene frequencies in samples of two language groups from Afghanistan, comprising 104 Pushtu and 179 Dari subjects living in Kabul, have been examined for 24 loci. Some systems suggest greater affinity to the west (e.g. the MS gene combination, the esterase D2 allele), some to the east (e.g.
D.F. Roberts +2 more
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Genetic polymorphism in an evolving population [PDF]
Physical Review E, 1998 We present a model for evolving population which maintains genetic polymorphism. By introducing random mutation in the model population at a constant rate, we observe that the population does not become extinct but survives, keeping diversity in the gene pool under abrupt environmental changes.
Daijin Kim, H. Y. Lee, M. Y. Choi
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, 2017 The human DNA is exposed to a number of changes, these changes are frequently carried out in one or few nucleotides called mutations, which can be caused by errors in the mechanisms of DNA replication and repair as well as by environmental factors; and these mutations can have deleterious effects and cause disease.
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