Genetic Polymorphism in Evolving Population [PDF]
Physical Review E, 1998 We present a model for evolving population which maintains genetic polymorphism. By introducing random mutation in the model population at a constant rate, we observe that the population does not become extinct but survives, keeping diversity in the gene pool under abrupt environmental changes.
Daijin Kim, H. Y. Lee, M. Y. Choi
arxiv +6 more sources
Blood ties: ABO is a trans-species polymorphism in primates [PDF]
, 2012 The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes responsible for A and B specificity in all species sequenced to date.
A. Venkat +38 more
arxiv +4 more sources
Replicators in Fine-grained Environment: Adaptation and Polymorphism [PDF]
Phys. Rev. Lett., 102, 058102 (2009), 2009 Selection in a time-periodic environment is modeled via the two-player replicator dynamics. For sufficiently fast environmental changes, this is reduced to a multi-player replicator dynamics in a constant environment. The two-player terms correspond to the time-averaged payoffs, while the three and four-player terms arise from the adaptation of the ...
Armen E. Allahverdyan +10 more
arxiv +3 more sources
Polymorphism of Genetic Ambigrams [PDF]
Virus Evolution, 2021 AbstractDouble synonyms in the genetic code can be used as a tool to test competing hypotheses regarding ambigrammatic narnavirus genomes. Applying the analysis to recent observations ofCulex narnavirus 1andZhejiang mosquito virus 3ambigrammatic viruses indicates that the open reading frame on the complementary strand of the segment coding for RNA ...
Gytis Dudas +3 more
openaire +5 more sources
Loss-of-function variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi-ethnic Asian cohort [PDF]
Clinical and Molecular Hepatology, 2021 Background/Aims 17β-hydroxysteroid dehydrogenase 13 (HSD17B13) variants were recently reported to have significantly lower odds of non-alcoholic fatty liver disease (NAFLD).
Yi-Wen Ting +7 more
doaj +1 more source
Association of Factor II G20210A, Factor V G1691A and methylenetetrahydrofolate reductase C677T gene polymorphism with different forms of myocardial infarction: ST segment elevation and non-ST segment elevation [PDF]
Vojnosanitetski Pregled, 2020 Background/Aim. Coagulation Factor II G20210A and Factor V G1691A variants are moderately associated with coronary artery disease. Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene C677T is associated with myocardial infarction (MI) in ...
Ćućuz-Jokić Milica +4 more
doaj +1 more source
Association of VDR gene ApaI polymorphism with obesity in Iranian population
Biomédica: revista del Instituto Nacional de Salud, 2021 Introduction: Identifying obesity risk factors as a health problem facing communities is crucial given its complexity. The vitamin D receptor gene has been reported as a possible cause of this disease.
Farzad Rashidi, Maryam Ostadsharif
doaj +1 more source
The distribution of genetic polymorphism of CYP3A5, CYP3A4 and ABCB1 in patients subjected to renal transplantation [PDF]
Vojnosanitetski Pregled, 2016 Background/Aim. Polymorphisms of genes which encode transporter P-glycoprotein and most important enzymes for tacrolimus pharmacokinetics can have significant influence reflecting on blood concentrations of this drug. The aim of this study was to examine
Vavić Neven +8 more
doaj +1 more source
Genome-wide association study of mitochondrial DNA in Chinese men identifies seven new susceptibility loci for high-altitude pulmonary oedema [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. High-altitude pulmonary oedema (HAPE), which normally occurs at altitudes higher than 3,000 m, is a potentially fatal disease due to hypoxia.
Tang Caizhi +4 more
doaj +1 more source
Forensic Application of ForenSeqTM DNA Signature Prep Kit in Zhengjiang She Ethnic Group
Fayixue Zazhi, 2021 ObjectiveTo evaluate the ability of the ForenSeqTM DNA Signature Prep kit （ForenSeq kit） in analyzing the sequence information of STRs in Zhejiang She ethnic group and its forensic application efficacy.MethodsA total of 50 Zhejiang She ethnic group ...
QU Yi-ling +12 more
doaj +1 more source