Association of prothrombin, FV Leiden and MTHFR gene polymorphisms in the Montenegrin patients with venous thromboembolism [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Polymorphisms of the factor V Leiden (FV G1691A), prothrombin (FII G20210A), and methylene-tetrahydrofolate reductase (MTHFR C677T) genes are the most commonly investigated inherited risk factors for developing venous thromboembolism (VTE)
Teofilov Slađana +4 more
doaj +1 more source
Association of Combined TCF7L2 and KCNQ1 Gene Polymorphisms with Diabetic Micro- and Macrovascular Complications in Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2021 Background Vascular complications are the major morbid consequences of type 2 diabetes mellitus (T2DM). The transcription factor 7-like 2 (TCF7L2), potassium voltage-gated channel subfamily Q member 1 (KCNQ1), and inwardly-rectifying potassium channel ...
Rujikorn Rattanatham +7 more
doaj +1 more source
Genome-wide association study of mitochondrial DNA in Chinese men identifies seven new susceptibility loci for high-altitude pulmonary oedema [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. High-altitude pulmonary oedema (HAPE), which normally occurs at altitudes higher than 3,000 m, is a potentially fatal disease due to hypoxia.
Tang Caizhi +4 more
doaj +1 more source
Loss-of-function variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi-ethnic Asian cohort [PDF]
Clinical and Molecular Hepatology, 2021 Background/Aims 17β-hydroxysteroid dehydrogenase 13 (HSD17B13) variants were recently reported to have significantly lower odds of non-alcoholic fatty liver disease (NAFLD).
Yi-Wen Ting +7 more
doaj +1 more source
Association of renin-angiotensin system genes polymorphism with progression of diabetic nephropathy in patients with type 1 diabetes mellitus [PDF]
Vojnosanitetski Pregled, 2014 Background/Aim. Diabetic nephropathy (DN) as a major microvascular complication of diabetes mellitus (DM) include a progressive increase in urinary albumin excretion in association with an increase in blood pressure and to end stage renal ...
Ilić Vesna +4 more
doaj +1 more source
Molecular Genetics & Genomic Medicine, 2023 Background Some cytokines are strongly implicated in the development of squamous cell carcinoma (SCC) such as the Macrophage migration inhibitory factor (MIF).
Elizabeth Guevara‐Gutiérrez +9 more
doaj +1 more source
Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans [PDF]
, 2020 OBJECTIVE: The role of genetic factors in the development of obesity is largely unreported in Sri Lankans. The Q223R (rs1137101) single nucleotide polymorphism (SNP) of the leptin receptor (LEPR) gene has been associated with obesity measures in various ...
Dalton, C.F. +3 more
core +1 more source
Association of MicroRNA Biogenesis Genes Polymorphisms with Ischemic Stroke Susceptibility and Post-Stroke Mortality [PDF]
Journal of Stroke, 2018 Background and Purpose MicroRNA (miRNA) expression has been examined in multiple conditions, including various cancers, neurological diseases, and cerebrovascular diseases, particularly stroke.
Jung Oh Kim +8 more
doaj +1 more source
The rs2304256 Polymorphism in Gene Is Associated with Protection for Type 1 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2021 Background Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and pro-inflammatory pathways in pancreatic β-cells through modulation of the type I interferon signaling
Felipe Mateus Pellenz +5 more
doaj +1 more source
Genetic Polymorphism of 16 X-STR Loci in Xinjiang Uygur Population
Fayixue Zazhi, 2022 ObjectiveTo study the genetic polymorphism and population genetic parameters of 16 X-STR loci in Xinjiang Uygur population.MethodsThe Goldeneye® DNA identification system 17X was used to amplify 16 X-STR loci in 502 unrelated individuals （251 females and
YUAN Chun-yan +10 more
doaj +1 more source