Factores genéticos y ambientales asociados con la respuesta a warfarina en pacientes colombianos
Biomédica: revista del Instituto Nacional de Salud, 2010 Introducción. La warfarina es un anticoagulante de difícil manejo por su estrecho margen terapéutico y los numerosos factores que influyen en la respuesta. Objetivo.
Carlos Isaza +6 more
doaj +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2013 Introducción. El retinoblastoma es un cáncer pediátrico de la retina originado por la expresión alterada o ausente de la proteína del retinoblastoma (pRb).
Martha Lucía Serrano, Juan José Yunis
doaj +1 more source
The rs2304256 Polymorphism in Gene Is Associated with Protection for Type 1 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2021 Background Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and pro-inflammatory pathways in pancreatic β-cells through modulation of the type I interferon signaling
Felipe Mateus Pellenz +5 more
doaj +1 more source
Genetic Polymorphisms in COL1A2 gene and the Risk of Tendinopathy: Case-Control Study [PDF]
Revista Brasileira de Ortopedia, 2023 Objective To evaluate the influence of polymorphisms on genes encoding type I collagen and the genetic susceptibility of tendinopathy. Methodology Case-control study involving 242 Brazilian athletes from different sports modalities (55 cases of ...
Lucas Rafael Lopes +7 more
doaj +1 more source
Genetic polymorphisms in sepsis
Pediatric Critical Care Medicine, 2005 Wide variability exists in the susceptibility to and outcome from sepsis even within similar intensive care unit populations. Some of this variability in the host may be due to genetic variation in genes coding for components of the innate immune response.To review the evidence for a genetic influence on the susceptibility to and outcome from sepsis ...
Mary K, Dahmer +3 more
openaire +3 more sources
Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism [PDF]
, 2003 Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response.
Konig, A. +8 more
core +1 more source
Genetic polymorphisms in Afghanistan
Annals of Human Biology, 1977 The gene frequencies in samples of two language groups from Afghanistan, comprising 104 Pushtu and 179 Dari subjects living in Kabul, have been examined for 24 loci. Some systems suggest greater affinity to the west (e.g. the MS gene combination, the esterase D2 allele), some to the east (e.g.
S S, Papiha, D F, Roberts, A G, Rahimi
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Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis. [PDF]
, 2006 Background: Pre-eclampsia is thought to have an important genetic component. Recently, pre-eclampsia has been associated in some studies with carriage of a common eNOS gene Glu298Asp polymorphism, a variant that leads to the replacement of glutamic ...
Nicolaides Kypros H +23 more
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Association of VDR gene ApaI polymorphism with obesity in Iranian population
Biomédica: revista del Instituto Nacional de Salud, 2021 Introduction: Identifying obesity risk factors as a health problem facing communities is crucial given its complexity. The vitamin D receptor gene has been reported as a possible cause of this disease.
Farzad Rashidi, Maryam Ostadsharif
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Leishmania major: genetic heterogeneity of Iranian isolates by single-strand conformation polymorphism and sequence analysis of ribosomal DNA internal transcribed spacer. [PDF]
, 2006 Protozoan parasites of Leishmania major are the causative agents of cutaneous leishmaniasis in different parts of Iran. We applied PCR-based methods to analyze L.
Mauricio, Isabel L +6 more
core +1 more source