FUNDAMENTO: Polimorfismos em genes relacionados ao desenvolvimento da aterosclerose, angiogênese e metabolismo da homocisteína (Hcy) podem ser fatores de risco para a doença arterial coronariana (DAC).
Alexandre Rodrigues Guerzoni +7 more
doaj +1 more source
Does the catechol-O-methyltransferase (COMT) Val158Met human polymorphism in influence procrastination? [PDF]
Genetic studies are enlightening how the expression of several genes influences neuronal activity and all facets of human normal and abnormal behaviour. Among these, a growing body of information shows that a few key genes regulating activity of central ...
Abate, Georgia +3 more
core +1 more source
Factores genéticos y ambientales asociados con la respuesta a warfarina en pacientes colombianos
Introducción. La warfarina es un anticoagulante de difícil manejo por su estrecho margen terapéutico y los numerosos factores que influyen en la respuesta. Objetivo.
Carlos Isaza +6 more
doaj +1 more source
Angiotensin II type 1 receptor gene polymorphism could influence renoprotective response to losartan treatment in type 1 diabetic patients with high urinary albumin excretion rate [PDF]
Background/Aim. Diabetic nephropathy (DN) is a clinical syndrome characterized by persistent albuminuria, increasing arterial blood pressure and progressive decline in glomerular filtration rate (GFR).
Dragović Tamara +6 more
doaj +1 more source
Introducción. El retinoblastoma es un cáncer pediátrico de la retina originado por la expresión alterada o ausente de la proteína del retinoblastoma (pRb).
Martha Lucía Serrano, Juan José Yunis
doaj +1 more source
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason +14 more
wiley +1 more source
Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle [PDF]
peer-reviewedSelection based on genetic polymorphisms requires accurate quantification of the effect or association of the polymorphisms with all traits of economic importance. The objective of this study was to estimate, using progeny performance data
Berry, Donagh +5 more
core
Maintenance of polymorphism in the orb weaving spider species Agalenatea redii (Araneae, Araneidae) [PDF]
The maintenance of polymorphism within populations may be the consequence of several elements of species life history such as use of space, activity rhythms, predation, parasitism and reproduction.
François, Olivier +3 more
core +2 more sources
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich +5 more
wiley +1 more source
The c.-1639g>A polymorphism of the VKORC1 gene and his influence on the therapeutic response during oral anticoagulants use [PDF]
Background/Aim. A single nucleotide polymorphism c.- 1639G>A in the promoter region of vitamin K-epoxide reductase (VKORC1) gene has been found to account for most of the variability in response to oral anticoagulants (OA). The aim of the study was to
Kovač Mirjana +3 more
doaj +1 more source

