Pharmacogenetics of antiretroviral drugs [PDF]
nema
Dragović Gordana +2 more
doaj +1 more source
Impact of mating systems on patterns of sequence polymorphism in flowering plants [PDF]
A fundamental challenge in population genetics and molecular evolution is to understand the forces shaping the patterns of genetic diversity within and among species.
Deborah Charlesworth +5 more
core +1 more source
Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene. [PDF]
Apolipoprotein AV (ApoAV) gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An MseI based RFLP analysis is the most commonly used method for genotyping this SNP.
Andrew T Hattersley +20 more
core +1 more source
Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: Evidence of small-study bias [PDF]
Background Inappropriate activation of the renin-angiotensin system may play a part in the development of preeclampsia. An insertion/deletion polymorphism within the angiotensin-I converting enzyme gene (ACE-I/D) has shown to be reliably associated with ...
Casas Juan P +39 more
core +1 more source
FUNDAMENTO: Existem evidências de associação entre o polimorfismo da apolipoproteína E (APOE) e a doença coronariana, entretanto há controvérsias. OBJETIVO: Avaliar a associação entre o número de vasos coronarianos acometidos por obstrução significativa ...
Arlisa Monteiro de Castro Dias +8 more
doaj +1 more source
FUNDAMENTO: Polimorfismos em genes relacionados ao desenvolvimento da aterosclerose, angiogênese e metabolismo da homocisteína (Hcy) podem ser fatores de risco para a doença arterial coronariana (DAC).
Alexandre Rodrigues Guerzoni +7 more
doaj +1 more source
The distribution of genetic polymorphism of CYP3A5, CYP3A4 and ABCB1 in patients subjected to renal transplantation [PDF]
Background/Aim. Polymorphisms of genes which encode transporter P-glycoprotein and most important enzymes for tacrolimus pharmacokinetics can have significant influence reflecting on blood concentrations of this drug. The aim of this study was to examine
Vavić Neven +8 more
doaj +1 more source
Genetic Polymorphism of 16 X-STR Loci in Xinjiang Uygur Population
ObjectiveTo study the genetic polymorphism and population genetic parameters of 16 X-STR loci in Xinjiang Uygur population.MethodsThe Goldeneye® DNA identification system 17X was used to amplify 16 X-STR loci in 502 unrelated individuals (251 females and
YUAN Chun-yan +10 more
doaj +1 more source
Killing them softly:managing pathogen polymorphism and virulence in spatially variable environments [PDF]
Understanding why pathogen populations are genetically variable is vital because genetic variation fuels evolution, which often hampers disease control efforts.
Vale, Pedro F; id_orcid, Vale, Pedro F.
core +1 more source
Forensic Application of ForenSeqTM DNA Signature Prep Kit in Zhengjiang She Ethnic Group
ObjectiveTo evaluate the ability of the ForenSeqTM DNA Signature Prep kit (ForenSeq kit) in analyzing the sequence information of STRs in Zhejiang She ethnic group and its forensic application efficacy.MethodsA total of 50 Zhejiang She ethnic group ...
QU Yi-ling +12 more
doaj +1 more source

