Loss-of-function variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi-ethnic Asian cohort [PDF]
Clinical and Molecular Hepatology, 2021 Background/Aims 17β-hydroxysteroid dehydrogenase 13 (HSD17B13) variants were recently reported to have significantly lower odds of non-alcoholic fatty liver disease (NAFLD).
Yi-Wen Ting +7 more
doaj +1 more source
Genome-wide association study of mitochondrial DNA in Chinese men identifies seven new susceptibility loci for high-altitude pulmonary oedema [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. High-altitude pulmonary oedema (HAPE), which normally occurs at altitudes higher than 3,000 m, is a potentially fatal disease due to hypoxia.
Tang Caizhi +4 more
doaj +1 more source
Association of prothrombin, FV Leiden and MTHFR gene polymorphisms in the Montenegrin patients with venous thromboembolism [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Polymorphisms of the factor V Leiden (FV G1691A), prothrombin (FII G20210A), and methylene-tetrahydrofolate reductase (MTHFR C677T) genes are the most commonly investigated inherited risk factors for developing venous thromboembolism (VTE)
Teofilov Slađana +4 more
doaj +1 more source
Association of Combined TCF7L2 and KCNQ1 Gene Polymorphisms with Diabetic Micro- and Macrovascular Complications in Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2021 Background Vascular complications are the major morbid consequences of type 2 diabetes mellitus (T2DM). The transcription factor 7-like 2 (TCF7L2), potassium voltage-gated channel subfamily Q member 1 (KCNQ1), and inwardly-rectifying potassium channel ...
Rujikorn Rattanatham +7 more
doaj +1 more source
Association of MicroRNA Biogenesis Genes Polymorphisms with Ischemic Stroke Susceptibility and Post-Stroke Mortality [PDF]
Journal of Stroke, 2018 Background and Purpose MicroRNA (miRNA) expression has been examined in multiple conditions, including various cancers, neurological diseases, and cerebrovascular diseases, particularly stroke.
Jung Oh Kim +8 more
doaj +1 more source
The relationship between tacrolimus concentration-dose ratio and genetic polymorphism in patients subjected to renal transplantation [PDF]
Vojnosanitetski Pregled, 2018 Background/Aim. Tacrolimus concentration-dose ratio as a potential therapeutic drug monitoring strategy was suggested to be used for the patients subjected to renal transplantation.
Rančić Nemanja +7 more
doaj +1 more source
Determinants of genetic diversity
Nature Reviews Genetics, 2016 Hans Ellegren, Nicolas Galtier
exaly +2 more sources
Pharmacogenetics of antiretroviral drugs [PDF]
Vojnosanitetski Pregled, 2012 nema
Dragović Gordana +2 more
doaj +1 more source
Alimentary Pharmacology and Therapeutics, 2020 Single nucleotide polymorphism–based genetic risk scores (GRS) model genetic risk as a continuum and can discriminate coeliac disease but have not been validated in clinic. Human leukocyte antigen (HLA) DQ gene testing is available in clinic but does not
S. Sharp +12 more
semanticscholar +1 more source
Proceedings of the Royal Society of London. Series B. Biological Sciences, 2020 The title of this Symposium ‘From Mendel’s factors to the genetic code’ emphasizes a single aspect of genetic research. That is unfortunate in a subject of such wide scope. Even in the most general terms, it naturally involves far more than analysing the
E. Ford
semanticscholar +1 more source