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Genetic linkage maps play fundamental roles in understanding genome structure, explaining genome formation events during evolution, and discovering the genetic bases of important traits.
John Z. Yu+14 more
semanticscholar +1 more source
Association of GPX1 Pro198Leu and SOD1 A251G polymorphisms with risk of acute kidney rejection [PDF]
Background/Aim: Acute rejection is one factor threatening the success of kidney transplantation. One of the factors that can cause graft rejection is oxidative stress.
Rayatpisheh Shima+2 more
doaj +1 more source
Mitochondrially-Encoded Adenosine Triphosphate Synthase 6 Gene Haplotype Variation Among World Population During 2003-2013 [PDF]
Background: Adaptation and natural selection serve as an important part of evolution. Adaptation in molecular level can lead to genetic drift which causes mutation of genetic material; one of which is polymorphism of mitochondrial DNA (mtDNA). The aim of
Dewanto, J. B. (Julius)+2 more
core +1 more source
MMP-3 polymorphism: Genetic marker in pathological processes (Review).
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that are collectively capable of cleaving virtually all extracellular matrix (ECM) substrates and play an important role in diverse physiological and pathological processes ...
F. B. A. Munhoz+2 more
semanticscholar +1 more source
Genetic polymorphisms in sepsis
Wide variability exists in the susceptibility to and outcome from sepsis even within similar intensive care unit populations. Some of this variability in the host may be due to genetic variation in genes coding for components of the innate immune response.To review the evidence for a genetic influence on the susceptibility to and outcome from sepsis ...
Michael W. Quasney+3 more
openaire +4 more sources
Genetic polymorphisms and folate status [PDF]
AbstractModerate hyperhomocysteinemia‐induced low folate status is an independent risk factor for cardiovascular disease, dementia, and depression. Folate is an essential cofactor in the one‐carbon metabolism pathway and is necessary in amino acid metabolism, purine and thymidylate synthesis, and DNA methylation.
Mami Hiraoka, Yasuo Kagawa
openaire +3 more sources
The genetic basis of a social polymorphism in halictid bees
The emergence of eusociality represents a major evolutionary transition from solitary to group reproduction. The most commonly studied eusocial species, honey bees and ants, represent the behavioral extremes of social evolution but lack close relatives ...
Sarah D. Kocher+5 more
semanticscholar +1 more source
Genetic Polymorphisms and Posttraumatic Complications [PDF]
Major trauma is the leading cause of death in young adults. Despite advances in prehospital system and treatment in hospital, mortality rates have not improved significantly over the past decades. Victims of severe injuries who survive the initial hours have great risk for additional life-threatening complicaitons, including uncontrollable infection ...
Jianxin Jiang, Wei Gu
openaire +2 more sources
A High-Resolution Single Nucleotide Polymorphism Genetic Map of the Mouse Genome
High-resolution genetic maps are required for mapping complex traits and for the study of recombination. We report the highest density genetic map yet created for any organism, except humans.
S. Shifman+6 more
semanticscholar +1 more source
Genetic polymorphisms and heart failure [PDF]
Heart failure is a complex clinical syndrome. There is evidence for a genetic contribution to the pathophysiology of heart failure. Considering the fundamental role of neurohormonal factors in the pathophysiology and progression of cardiac dysfunction and hypertrophy, variants of genes involved in this system are logical candidate genes in heart ...
Bruno H. Stricker+5 more
openaire +3 more sources